1KF4
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![BU of 1kf4 by Molmil](/molmil-images/mine/1kf4) | Atomic Resolution Structure of RNase A at pH 6.3 | 分子名称: | SULFATE ION, pancreatic ribonuclease | 著者 | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | 登録日 | 2001-11-19 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic resolution structures of ribonuclease A at six pH values. Acta Crystallogr.,Sect.D, 58, 2002
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3NKK
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![BU of 3nkk by Molmil](/molmil-images/mine/3nkk) | Trypsin in complex with fluorine containing fragment | 分子名称: | 3-fluoro-4-methylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... | 著者 | Schiering, N, Vulpetti, A, Dalvit, C. | 登録日 | 2010-06-20 | 公開日 | 2010-11-10 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments. Proteins, 78, 2010
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3MTH
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![BU of 3mth by Molmil](/molmil-images/mine/3mth) | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | 分子名称: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... | 著者 | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | 登録日 | 1995-09-13 | 公開日 | 1996-01-29 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
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3NNN
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![BU of 3nnn by Molmil](/molmil-images/mine/3nnn) | BeF3 Activated DrrD Receiver Domain | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA BINDING RESPONSE REGULATOR D, MAGNESIUM ION | 著者 | Robinson, V.L, Stock, A.M. | 登録日 | 2010-06-23 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
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1KT4
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3NSH
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![BU of 3nsh by Molmil](/molmil-images/mine/3nsh) | BACE-1 in complex with ELN475957 | 分子名称: | Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide | 著者 | Probst, G.D, Bowers, S, Sealy, J.M, Brecht, E, Yao, N. | 登録日 | 2010-07-01 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg.Med.Chem.Lett., 20, 2010
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1KE9
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![BU of 1ke9 by Molmil](/molmil-images/mine/1ke9) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 3-{[4-({[AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE | 分子名称: | 3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE, Cell division protein kinase 2 | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.M, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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3NUP
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![BU of 3nup by Molmil](/molmil-images/mine/3nup) | CDK6 (monomeric) in complex with inhibitor | 分子名称: | 4-[3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(1-methylpiperidin-4-yl)pyrimidin-2-amine, Cell division protein kinase 6 | 著者 | Chopra, R. | 登録日 | 2010-07-07 | 公開日 | 2010-12-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J.Med.Chem., 53, 2010
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3NUX
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![BU of 3nux by Molmil](/molmil-images/mine/3nux) | CDK6 (monomeric) in complex with inhibitor | 分子名称: | 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine, Cell division protein kinase 6 | 著者 | Chopra, R. | 登録日 | 2010-07-07 | 公開日 | 2010-12-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J.Med.Chem., 53, 2010
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3NU3
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![BU of 3nu3 by Molmil](/molmil-images/mine/3nu3) | Wild Type HIV-1 Protease with Antiviral Drug Amprenavir | 分子名称: | CHLORIDE ION, GLYCEROL, Protease, ... | 著者 | Wang, Y.-F, Kovalevsky, A.Y, Weber, I.T. | 登録日 | 2010-07-06 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters. Febs J., 277, 2010
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1KWY
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![BU of 1kwy by Molmil](/molmil-images/mine/1kwy) | Rat mannose protein A complexed with man-a13-man. | 分子名称: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-01-30 | 公開日 | 2002-07-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
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3NV6
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![BU of 3nv6 by Molmil](/molmil-images/mine/3nv6) | Crystal Structure of Camphor-Bound CYP101D2 | 分子名称: | CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. | 登録日 | 2010-07-08 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structure of CYP101D2 unveils a potential path for substrate entry into the active site Biochem.J., 433, 2011
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1KF7
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![BU of 1kf7 by Molmil](/molmil-images/mine/1kf7) | Atomic Resolution Structure of RNase A at pH 8.0 | 分子名称: | pancreatic ribonuclease | 著者 | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | 登録日 | 2001-11-19 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Atomic resolution structures of ribonuclease A at six pH values. Acta Crystallogr.,Sect.D, 58, 2002
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3NWQ
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1KE7
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![BU of 1ke7 by Molmil](/molmil-images/mine/1ke7) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE | 分子名称: | 3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE, Cell division protein kinase 2 | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.H, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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3O17
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3O4M
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![BU of 3o4m by Molmil](/molmil-images/mine/3o4m) | Crystal structure of porcine pancreatic phospholipase A2 in complex with 1,2-dihydroxybenzene | 分子名称: | CALCIUM ION, CATECHOL, Phospholipase A2, ... | 著者 | Dileep, K.V, Tintu, I, Karthe, P, Mandal, P.K, Haridas, M, Sadasivan, C. | 登録日 | 2010-07-27 | 公開日 | 2010-08-25 | 最終更新日 | 2011-11-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Binding to PLA(2) may contribute to the anti-inflammatory activity of catechol Chem.Biol.Drug Des., 2011
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3NR6
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![BU of 3nr6 by Molmil](/molmil-images/mine/3nr6) | Crystal structure of xenotropic murine leukemia virus-related virus (XMRV) protease | 分子名称: | PHOSPHATE ION, POTASSIUM ION, Protease p14 | 著者 | Lubkowski, J, Li, M, Gustchina, A, Zhou, D, Dauter, Z, Wlodawer, A. | 登録日 | 2010-06-30 | 公開日 | 2011-02-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Crystal structure of XMRV protease differs from the structures of other retropepsins. Nat.Struct.Mol.Biol., 18, 2011
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3NPL
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![BU of 3npl by Molmil](/molmil-images/mine/3npl) | Structure of Ru(bpy)2(A-Phen)(K97C) P450 BM3 heme domain, a ruthenium modified P450 BM3 mutant | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | 著者 | Ener, M, Lee, Y.-T, Goodin, D.B, Winkler, J.R, Gray, H.B, Cheruzel, L. | 登録日 | 2010-06-28 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of Ru(bpy)2(A-Phen)(K97C) P450 BM3 heme domain, a ruthenium modified P450 BM3 mutant To be Published
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3NWW
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![BU of 3nww by Molmil](/molmil-images/mine/3nww) | P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor | 分子名称: | 1-[2-(2-{[2-(dimethylamino)ethyl]amino}-6-{2-[(1-methylethyl)amino]-1,3-thiazol-5-yl}pyrimidin-4-yl)benzyl]-3-ethylurea, Mitogen-activated protein kinase 14 | 著者 | Sack, J.S. | 登録日 | 2010-07-12 | 公開日 | 2010-09-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3O20
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![BU of 3o20 by Molmil](/molmil-images/mine/3o20) | Electron transfer complexes:experimental mapping of the Redox-dependent Cytochrome C electrostatic surface | 分子名称: | Cytochrome c, HEME C, NITRATE ION | 著者 | De March, M, De Zorzi, R, Casini, A, Messori, L, Geremia, S, Demitri, N, Gabbiani, C, Guerri, A. | 登録日 | 2010-07-22 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition. J. Inorg. Biochem., 135, 2014
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3O9B
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![BU of 3o9b by Molmil](/molmil-images/mine/3o9b) | Crystal Structure of wild-type HIV-1 Protease in Complex with kd25 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)propyl]carbamate, ACETATE ION, GLYCEROL, ... | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2010-08-04 | 公開日 | 2011-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem.Biol., 20, 2013
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3O9L
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![BU of 3o9l by Molmil](/molmil-images/mine/3o9l) | Design and optimisation of new piperidines as renin inhibitors | 分子名称: | (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Corminboeuf, O, Bezencon, O, Grisostomi, C, Remen, L, Richard-Bildstein, S, Bur, D, Prade, L, Hess, P, Strickner, P, Treiber, A. | 登録日 | 2010-08-04 | 公開日 | 2011-03-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and optimization of new piperidines as renin inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3OAD
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![BU of 3oad by Molmil](/molmil-images/mine/3oad) | Design and optimization of new piperidines as renin inhibitors | 分子名称: | (3S,4R)-N-[2-chloro-5-(2-methoxyethyl)benzyl]-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}-4-hydroxypiperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Prade, L. | 登録日 | 2010-08-05 | 公開日 | 2010-11-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Design and optimization of new piperidines as renin inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3NU6
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