8E13
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6Y2B
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![BU of 6y2b by Molmil](/molmil-images/mine/6y2b) | Crystal structure of HLA-B2709 complexed with the nona-peptide mQ | 分子名称: | Beta-2-microglobulin, GLYCEROL, Lymphocyte antigen HLA-B27, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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5C0G
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![BU of 5c0g by Molmil](/molmil-images/mine/5c0g) | HLA-A02 carrying YLGGPDFPTI | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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4U1J
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![BU of 4u1j by Molmil](/molmil-images/mine/4u1j) | HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2014-07-15 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology, 12, 2015
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4WW1
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![BU of 4ww1 by Molmil](/molmil-images/mine/4ww1) | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8 and Beta Chain-TRBV7-8 | 分子名称: | TCR Alpha Chain-TRAV21-TRAJ8, TCR Beta Chain-TRBV7-8 | 著者 | Le Nours, J, Praveena, T, Pellicci, D.G, Lim, R.T, Besra, G, Howell, A.R, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | 登録日 | 2014-11-10 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nat Commun, 7, 2016
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6Y27
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![BU of 6y27 by Molmil](/molmil-images/mine/6y27) | Crystal structure of HLA-B2709 complexed with the nona-peptide mA | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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5WL1
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![BU of 5wl1 by Molmil](/molmil-images/mine/5wl1) | Crystal Structure of Human CD1b in Complex with PG | 分子名称: | (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Shahine, A, Gras, S, Rossjohn, J. | 登録日 | 2017-07-25 | 公開日 | 2017-11-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol, 2, 2017
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6PYW
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6UCE
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5N1Y
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![BU of 5n1y by Molmil](/molmil-images/mine/5n1y) | HLA-A02 carrying MVWGPDPLYV | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2017-02-06 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J. Clin. Invest., 126, 2016
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6P2C
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![BU of 6p2c by Molmil](/molmil-images/mine/6p2c) | Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | 著者 | Li, L, Batliwala, M, Bouvier, M. | 登録日 | 2019-05-21 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | 主引用文献 | ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation. J.Biol.Chem., 294, 2019
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7KGP
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![BU of 7kgp by Molmil](/molmil-images/mine/7kgp) | Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N316-324 | 分子名称: | ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ... | 著者 | Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S. | 登録日 | 2020-10-18 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | 主引用文献 | The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule. Iscience, 24, 2021
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7X1B
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8ROO
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![BU of 8roo by Molmil](/molmil-images/mine/8roo) | Crystal structure of HLA B*18:01 in complex with YERMCNIL, an 8-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Influenza A derived peptide/Nucleoprotein, ... | 著者 | Murdolo, L.D, Maddumage, J.C, Gras, S. | 登録日 | 2024-01-11 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of HLA B*18:01 in complex with YERMCNIL, an 8-mer epitope from Influenza A To Be Published
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1RUP
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![BU of 1rup by Molmil](/molmil-images/mine/1rup) | Crystal structure (G) of native cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at APS beamline 19-ID | 分子名称: | BENZOIC ACID, GLYCEROL, immunoglobulin igg2a, ... | 著者 | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | 登録日 | 2003-12-11 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution. Proc.Natl.Acad.Sci.USA, 110, 2004
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4FXL
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![BU of 4fxl by Molmil](/molmil-images/mine/4fxl) | Crystal structure of the D76N Beta-2 Microglobulin mutant | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. | 登録日 | 2012-07-03 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin. N.Engl.J.Med., 366, 2012
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2BNU
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![BU of 2bnu by Molmil](/molmil-images/mine/2bnu) | Structural and kinetic basis for heightened immunogenicity of T cell vaccines | 分子名称: | T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION | 著者 | Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, Van Der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V. | 登録日 | 2005-04-04 | 公開日 | 2005-05-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines. J.Exp.Med., 201, 2005
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6O53
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![BU of 6o53 by Molmil](/molmil-images/mine/6o53) | Structure of HLA-A2:01 with peptide MM96 | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | 著者 | Ying, G, Bitra, A, Zajonc, D.M. | 登録日 | 2019-03-01 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Front Immunol, 10, 2019
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6J2A
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![BU of 6j2a by Molmil](/molmil-images/mine/6j2a) | The structure of HLA-A*3003/NP44 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, NP44 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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5WMQ
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3MRB
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![BU of 3mrb by Molmil](/molmil-images/mine/3mrb) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide A7H variant | 分子名称: | 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Reiser, J.-B, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with short peptide To be Published
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1OGA
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![BU of 1oga by Molmil](/molmil-images/mine/1oga) | A structural basis for immunodominant human T-cell receptor recognition. | 分子名称: | BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y. | 登録日 | 2003-04-28 | 公開日 | 2003-06-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A Structural Basis for Immunodominant Human T Cell Receptor Recognition Nat.Immunol., 4, 2003
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4QRS
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![BU of 4qrs by Molmil](/molmil-images/mine/4qrs) | Crystal Structure of HLA B*0801 in complex with ELK_IYM, ELKRKMIYM | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Twist, K.-A, Rossjohn, J. | 登録日 | 2014-07-02 | 公開日 | 2014-12-10 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Sci Rep, 4, 2014
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2NW2
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4QRT
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![BU of 4qrt by Molmil](/molmil-images/mine/4qrt) | Crystal Structure of HLA B*0801 in complex with ELN_YYM, ELNRKMIYM | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Twist, K.-A, Rossjohn, J. | 登録日 | 2014-07-02 | 公開日 | 2014-07-16 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Sci Rep, 4, 2014
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