3S8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s8c by Molmil](/molmil-images/mine/3s8c) | Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | 登録日 | 2011-05-27 | 公開日 | 2012-04-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
|
|
3RSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rsr by Molmil](/molmil-images/mine/3rsr) | Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase | 分子名称: | 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G. | 登録日 | 2011-05-02 | 公開日 | 2012-11-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol.Cancer Ther., 11, 2012
|
|
3TBA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tba by Molmil](/molmil-images/mine/3tba) | Structure of Yeast Ribonucleotide Reductase 1 Q288A with dGTP and ADP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C. | 登録日 | 2011-08-05 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
|
|
6MW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mw3 by Molmil](/molmil-images/mine/6mw3) | EM structure of Bacillus subtilis ribonucleotide reductase inhibited filament composed of NrdE alpha subunit and NrdF beta subunit with dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase, Ribonucleoside-diphosphate reductase NrdF beta subunit | 著者 | Thomas, W.C, Bacik, J.P, Kaelber, J.T, Ando, N. | 登録日 | 2018-10-29 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.65 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
|
|
3TB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tb9 by Molmil](/molmil-images/mine/3tb9) | Structure of Yeast Ribonucleotide Reductase 1 Q288A with AMPPNP and CDP | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | 登録日 | 2011-08-05 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
|
|
6LKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkm by Molmil](/molmil-images/mine/6lkm) | Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-sulfonamide | 分子名称: | 5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-sulfonamide, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | 著者 | Miyahara, S, Chong, K.T, Suzuki, T. | 登録日 | 2019-12-19 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity To be published
|
|
3S8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s8b by Molmil](/molmil-images/mine/3s8b) | Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | 登録日 | 2011-05-27 | 公開日 | 2012-04-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
|
|
6MVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mve by Molmil](/molmil-images/mine/6mve) | Reduced X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | 登録日 | 2018-10-25 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
|
|
6MT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mt9 by Molmil](/molmil-images/mine/6mt9) | X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | 登録日 | 2018-10-19 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
|
|
6MV9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mv9 by Molmil](/molmil-images/mine/6mv9) | X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase, ... | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | 登録日 | 2018-10-24 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
|
|
6MYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6myx by Molmil](/molmil-images/mine/6myx) | EM structure of Bacillus subtilis ribonucleotide reductase inhibited double-helical filament of NrdE alpha subunit with dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase | 著者 | Thomas, W.C, Bacik, J.P, Chen, J.Z, Ando, N. | 登録日 | 2018-11-02 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
|
|
3S8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s8a by Molmil](/molmil-images/mine/3s8a) | Structure of Yeast Ribonucleotide Reductase R293A with dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | 登録日 | 2011-05-27 | 公開日 | 2012-04-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
|
|
2CVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cvx by Molmil](/molmil-images/mine/2cvx) | Structures of Yeast Ribonucleotide Reductase I | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | 登録日 | 2005-06-14 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2CVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cvv by Molmil](/molmil-images/mine/2cvv) | Structures of Yeast Ribonucleotide Reductase I | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ... | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | 登録日 | 2005-06-14 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2CVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cvt by Molmil](/molmil-images/mine/2cvt) | Structures of Yeast Ribonucleotide Reductase I | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | 登録日 | 2005-06-14 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2CVY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cvy by Molmil](/molmil-images/mine/2cvy) | Structures of Yeast Ribonucleotide Reductase I | 分子名称: | 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | 登録日 | 2005-06-14 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1XJE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xje by Molmil](/molmil-images/mine/1xje) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1XJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjm by Molmil](/molmil-images/mine/1xjm) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP complex | 分子名称: | MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ribonucleotide reductase, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-12-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
2BQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bq1 by Molmil](/molmil-images/mine/2bq1) | Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, FE (III) ION, MAGNESIUM ION, ... | 著者 | Uppsten, M, Farnegardh, M, Domkin, V, Uhlin, U. | 登録日 | 2005-04-26 | 公開日 | 2006-05-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.99 Å) | 主引用文献 | The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into its Mechanism of Action J.Mol.Biol., 359, 2006
|
|
1XJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjk by Molmil](/molmil-images/mine/1xjk) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1XJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjf by Molmil](/molmil-images/mine/1xjf) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-12-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1XJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjg by Molmil](/molmil-images/mine/1xjg) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-UDP complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-12-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
|
|
1XJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjj by Molmil](/molmil-images/mine/1xjj) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-12-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2005
|
|
1XJN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjn by Molmil](/molmil-images/mine/1xjn) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-CDP complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
|
|
2CVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cvu by Molmil](/molmil-images/mine/2cvu) | Structures of Yeast Ribonucleotide Reductase I | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | 登録日 | 2005-06-14 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|