2VD9
 
 | | The crystal structure of alanine racemase from Bacillus anthracis (BA0252) with bound L-Ala-P | | 分子名称: | (1S)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]ETHYLPHOSPHONIC ACID, ALANINE RACEMASE, CHLORIDE ION, ... | | 著者 | Au, K, Ren, J, Walter, T.S, Harlos, K, Nettleship, J.E, Owens, R.J, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | 登録日 | 2007-10-01 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
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4Y2W
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8AHW
 | | Structure of DCS-resistant variant D322N of alanine racemase from Mycobacterium tuberculosis | | 分子名称: | 1,2-ETHANEDIOL, Alanine racemase, GLYCEROL | | 著者 | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | | 登録日 | 2022-07-22 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis .
Acs Bio Med Chem Au, 3, 2023
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1L6F
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine | | 分子名称: | ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase | | 著者 | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | 登録日 | 2002-03-09 | | 公開日 | 2002-06-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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8B8H
 | | Structure of DCS-resistant variant D322N of alanine racemase from M. tuberculosis in complex with DCS | | 分子名称: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, Alanine racemase, ... | | 著者 | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | | 登録日 | 2022-10-04 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis .
Acs Bio Med Chem Au, 3, 2023
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6SCZ
 | | Mycobacterium tuberculosis alanine racemase inhibited by DCS | | 分子名称: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | de Chiara, C, Purkiss, A, Prosser, G, Homsak, M, de Carvalho, L.P.S. | | 登録日 | 2019-07-26 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition.
Nat.Chem.Biol., 16, 2020
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1L6G
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine | | 分子名称: | N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase | | 著者 | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | 登録日 | 2002-03-10 | | 公開日 | 2002-06-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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1FTX
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2VD8
 | | The crystal structure of alanine racemase from Bacillus anthracis (BA0252) | | 分子名称: | ALANINE RACEMASE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Au, K, Ren, J, Walter, T.S, Harlos, K, Nettleship, J.E, Owens, R.J, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | 登録日 | 2007-10-01 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
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4XBJ
 | | Y274F alanine racemase from E. coli inhibited by l-ala-p | | 分子名称: | Alanine racemase, biosynthetic, SULFATE ION, ... | | 著者 | Squire, C.J, Yosaatmadja, Y, Patrick, W.M. | | 登録日 | 2014-12-17 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.
J.Biol.Chem., 291, 2016
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2ODO
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3KW3
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1BD0
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1RCQ
 | | The 1.45 A crystal structure of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms | | 分子名称: | D-LYSINE, PYRIDOXAL-5'-PHOSPHATE, catabolic alanine racemase DadX | | 著者 | Le Magueres, P, Im, H, Dvorak, A, Strych, U, Benedik, M, Krause, K.L. | | 登録日 | 2003-11-04 | | 公開日 | 2004-06-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms.
Biochemistry, 42, 2003
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1NIU
 | | ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM L-CYCLOSERINE | | 分子名称: | Alanine Racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | 著者 | Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D. | | 登録日 | 2002-12-26 | | 公開日 | 2003-09-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry, 42, 2003
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1EPV
 | | ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM D-CYCLOSERINE | | 分子名称: | ALANINE RACEMASE, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | 著者 | Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D. | | 登録日 | 2000-03-29 | | 公開日 | 2003-01-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry, 42, 2003
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2RJG
 | | Crystal structure of biosynthetic alaine racemase from Escherichia coli | | 分子名称: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. | | 登録日 | 2007-10-15 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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4FS9
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1XFC
 | | The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site | | 分子名称: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | LeMagueres, P, Im, H, Ebalunode, J, Strych, U, Benedik, M.J, Briggs, J.M, Kohn, H, Krause, K.L. | | 登録日 | 2004-09-14 | | 公開日 | 2005-08-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site.
Biochemistry, 44, 2005
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4BEQ
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6Q70
 | | Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of HEPES | | 分子名称: | Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
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4BF5
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4BHY
 | | Structure of alanine racemase from Aeromonas hydrophila | | 分子名称: | ALANINE RACEMASE | | 著者 | Otero, L.H, Carrasco-Lopez, C, Bernardo-Garcia, N, Hermoso, J.A. | | 登録日 | 2013-04-09 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural Basis for the Broad Specificity of a New Family of Amino-Acid Racemases.
Acta Crystallogr.,Sect.D, 70, 2014
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4LUS
 | | alanine racemase [Clostridium difficile 630] | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, Alanine racemase, GLYCEROL | | 著者 | Asojo, O.A. | | 登録日 | 2013-07-25 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630.
Acta Crystallogr.,Sect.D, 70, 2014
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6Q71
 | | Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of Bis-Tris propane | | 分子名称: | Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
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