4UUJ
| POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | 著者 | Lenaeus, M.J, Burdette, D, Wagner, T, Focia, P.J, Gross, A. | 登録日 | 2014-07-29 | 公開日 | 2014-08-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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4X8A
| NavMS pore and C-terminal domain grown from protein purified in LiCl | 分子名称: | HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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4X88
| E178D Selectivity filter mutant of NavMS voltage-gated pore | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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3STZ
| KcsA potassium channel mutant Y82C with nitroxide spin label | 分子名称: | POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Voltage-gated potassium channel, ... | 著者 | Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E. | 登録日 | 2011-07-11 | 公開日 | 2012-04-18 | 最終更新日 | 2012-10-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels. Structure, 20, 2012
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3STL
| KcsA potassium channel mutant Y82C with Cadmium bound | 分子名称: | CADMIUM ION, POTASSIUM ION, Voltage-gated potassium channel, ... | 著者 | Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E. | 登録日 | 2011-07-11 | 公開日 | 2012-04-18 | 最終更新日 | 2012-10-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels. Structure, 20, 2012
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3WKV
| Voltage-gated proton channel: VSOP/Hv1 chimeric channel | 分子名称: | Ion channel | 著者 | Takeshita, K, Sakata, S, Yamashita, E, Fujiwara, Y, Kawanabe, A, Kurokawa, T, Okochi, Y, Matsuda, M, Narita, H, Okamura, Y, Nakagawa, A. | 登録日 | 2013-10-31 | 公開日 | 2014-03-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.453 Å) | 主引用文献 | X-ray crystal structure of voltage-gated proton channel. Nat.Struct.Mol.Biol., 21, 2014
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5IWK
| Structure of Transient Receptor Potential (TRP) channel TRPV6 | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2016-03-22 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.247 Å) | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
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5J8V
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4XDJ
| Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, ... | 著者 | Pike, A.C.W, Dong, Y.Y, Mackenzie, A, Mukhopadhyay, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2014-12-19 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
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4LTR
| Bacterial sodium channel, His245Gly mutant, I222 space group | 分子名称: | Ion transport protein | 著者 | Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L. | 登録日 | 2013-07-23 | 公開日 | 2013-10-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (5.8 Å) | 主引用文献 | Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels. J.Mol.Biol., 426, 2014
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5IWN
| Bacterial sodium channel pore domain, high bromide | 分子名称: | BROMIDE ION, Ion transport protein | 著者 | Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L. | 登録日 | 2016-03-22 | 公開日 | 2016-03-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation. Cell, 164, 2016
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5IWP
| Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2016-03-22 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
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4LTQ
| Bacterial sodium channel in low calcium, P42 space group | 分子名称: | Ion transport protein | 著者 | Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L. | 登録日 | 2013-07-23 | 公開日 | 2013-10-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | 主引用文献 | Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels. J.Mol.Biol., 426, 2014
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4MS2
| Structural basis of Ca2+ selectivity of a voltage-gated calcium channel | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2013-09-18 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel. Nature, 505, 2014
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4MTF
| Structural Basis of Ca2+ Selectivity of a Voltage-gated Calcium Channel | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2013-09-19 | 公開日 | 2013-11-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel. Nature, 505, 2014
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4XDL
| Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with a brominated fluoxetine derivative. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[2-bromanyl-4-(trifluoromethyl)phenoxy]-N-methyl-3-phenyl-propan-1-amine, CADMIUM ION, ... | 著者 | Mackenzie, A, Pike, A.C.W, Dong, Y.Y, Mukhopadhyay, S, Ruda, G.F, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2014-12-19 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
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4X89
| NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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4XDK
| Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine | 分子名称: | (3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, (3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Pike, A.C.W, Dong, Y.Y, Mackenzie, A, Mukhopadhyay, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2014-12-19 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
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6FOO
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1R3J
| potassium channel KcsA-Fab complex in high concentration of Tl+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1S5H
| Potassium Channel Kcsa-Fab Complex T75C mutant in K+ | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ... | 著者 | Mackinnon, R, Zhou, M. | 登録日 | 2004-01-20 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution. J.Mol.Biol., 338, 2004
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1R3L
| potassium channel KcsA-Fab complex in Cs+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1R3I
| potassium channel KcsA-Fab complex in Rb+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1R3K
| potassium channel KcsA-Fab complex in low concentration of Tl+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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2ATK
| Structure of a mutant KcsA K+ channel | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ... | 著者 | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E. | 登録日 | 2005-08-25 | 公開日 | 2006-03-07 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular determinants of gating at the potassium-channel selectivity filter. Nat.Struct.Mol.Biol., 13, 2006
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