PDB: 115 件ウェブページステータス検索Chemie searchBIRD

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1Q3G	MurA (Asp305Ala) liganded with tetrahedral reaction intermediate 分子名称: 1,2-ETHANEDIOL, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, UDP-N-acetylglucosamine 1-carboxyvinyltransferase 著者 Eschenburg, S, Kabsch, W, Healy, M.L, Schonbrunn, E. 登録日 2003-07-29 公開日 2003-12-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States. J.Biol.Chem., 278, 2003
3ZH4	crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate 分子名称: CITRATE ANION, DI(HYDROXYETHYL)ETHER, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE 著者 Gutierrez-Fernandez, J, Hermoso, J.A. 登録日 2012-12-20 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Heteroresistance to Fosfomycin is Predominant in Streptococcus Pneumoniae and Depends on Mura1 Gene. Antimicrob.Agents Chemother., 57, 2013
1RF6	Structural Studies of Streptococcus pneumoniae EPSP Synthase in S3P-GLP Bound State 分子名称: 5-enolpyruvylshikimate-3-phosphate synthase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE 著者 Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. 登録日 2003-11-07 公開日 2004-02-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state. Mol.Microbiol., 51, 2004
1YBG	MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid 分子名称: N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID, UDP-N-acetylglucosamine 1-carboxyvinyltransferase 著者 Eschenburg, S, Priestman, M.A, Abdul-Latif, F.A, Delachaume, C, Fassy, F, Schonbrunn, E. 登録日 2004-12-20 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA). J.Biol.Chem., 280, 2005
1UAE	STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE 分子名称: UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, [(1R)-1-hydroxypropyl]phosphonic acid 著者 Skarzynski, T. 登録日 1996-09-30 公開日 1997-09-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin. Structure, 4, 1996
3UPK	E. cloacae MURA in complex with UNAG 分子名称: 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2011-11-18 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA). J.Biol.Chem., 287, 2012
3V5V	UNLIGANDED E.CLOACAE C115D MURA 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2011-12-16 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA). J.Biol.Chem., 287, 2012
1P88	Substrate-induced structural changes to the isolated N-terminal domain of 5-enolpyruvylshikimate-3-phosphate synthase 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase 著者 Young, J.K, Stauffer, M.E, Kim, H.J, Helms, G.L, Evans, J.N.S. 登録日 2003-05-06 公開日 2004-11-02 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Letter: Substrate-induced structural changes to the isolated N-terminal domain of 5-enolpyruvylshikimate-3-phosphate synthase To be Published
2AA9	EPSP synthase liganded with shikimate 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID 著者 Priestman, M.A, Healy, M.L, Funke, T, Becker, A, Schonbrunn, E. 登録日 2005-07-13 公開日 2006-02-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. Febs Lett., 579, 2005
3ZH3	crystal structure of S. pneumoniae D39 native MurA1 分子名称: UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE 著者 Gutierrez-Fernandez, J, Hermoso, J.A. 登録日 2012-12-20 公開日 2013-04-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Heteroresistance to Fosfomycin is Predominant in Streptococcus Pneumoniae and Depends on Mura1 Gene. Antimicrob.Agents Chemother., 57, 2013
2AAY	EPSP synthase liganded with shikimate and glyphosate 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, ... 著者 Priestman, M.A, Healy, M.L, Funke, T, Becker, A. 登録日 2005-07-14 公開日 2006-02-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. Febs Lett., 579, 2005
1DLG	CRYSTAL STRUCTURE OF THE C115S ENTEROBACTER CLOACAE MURA IN THE UN-LIGANDED STATE 分子名称: CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE MURA 著者 Schonbrunn, E, Eschenburg, S, Krekel, F, Luger, K, Amrhein, N. 登録日 1999-12-09 公開日 2000-04-12 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA. Biochemistry, 39, 2000
1EJD	Crystal structure of unliganded mura (type1) 分子名称: CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE 著者 Eschenburg, S, Schonbrunn, E. 登録日 2000-03-02 公開日 2000-10-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Comparative X-ray analysis of the un-liganded fosfomycin-target murA. Proteins, 40, 2000
1EPS	STRUCTURE AND TOPOLOGICAL SYMMETRY OF THE GLYPHOSPHATE 5-ENOL-PYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE: A DISTINCTIVE PROTEIN FOLD 分子名称: 5-ENOL-PYRUVYL-3-PHOSPHATE SYNTHASE 著者 Stallings, W.C, Abdel-Meguid, S.S, Lim, L.W, Shieh, H.-S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M. 登録日 1991-04-05 公開日 1993-07-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold. Proc.Natl.Acad.Sci.USA, 88, 1991
1EJC	Crystal structure of unliganded mura (type2) 分子名称: GLYCEROL, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE 著者 Eschenburg, S, Schonbrunn, E. 登録日 2000-03-02 公開日 2000-10-25 最終更新日 2011-07-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comparative X-ray analysis of the un-liganded fosfomycin-target murA. Proteins, 40, 2000
1EYN	Structure of mura liganded with the extrinsic fluorescence probe ANS 分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, GLYCEROL, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE 著者 Schonbrunn, E, Eschenburg, S, Luger, K, Kabsch, W, Amrhein, N. 登録日 2000-05-07 公開日 2000-06-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA. Proc.Natl.Acad.Sci.USA, 97, 2000
1G6T	STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE 分子名称: EPSP SYNTHASE, FORMIC ACID, PHOSPHATE ION, ... 著者 Schonbrunn, E, Eschenburg, S, Shuttleworth, W, Schloss, J.V, Amrhein, N, Evans, J.N.S, Kabsch, W. 登録日 2000-11-07 公開日 2001-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail. Proc.Natl.Acad.Sci.USA, 98, 2001
1G6S	STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE 分子名称: EPSP SYNTHASE, FORMIC ACID, GLYPHOSATE, ... 著者 Schonbrunn, E, Eschenburg, S, Shuttleworth, W, Schloss, J.V, Amrhein, N, Evans, J.N.S, Kabsch, W. 登録日 2000-11-07 公開日 2001-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail. Proc.Natl.Acad.Sci.USA, 98, 2001
7TBU	Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (EPSPS) domain of Aro1 from Candida albicans in complex with shikimate-3-phosphate 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-enolpyruvylshikimate-3-phosphate synthase, SHIKIMATE-3-PHOSPHATE 著者 Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-12-22 公開日 2022-03-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
7TB0	E. faecium MurAA in complex with fosfomycin and UNAG 分子名称: CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... 著者 Zhou, Y, Shamoo, Y. 登録日 2021-12-21 公開日 2022-12-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Enolpyruvate transferase MurAA A149E , identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA-MurG interaction. J.Biol.Chem., 299, 2023
7TM4	Crystal structure of apo 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, NITRATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-01-19 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of apo 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae To be published
4E7D	E. cloacae MurA in complex with UDP 分子名称: 1,2-ETHANEDIOL, ACETATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2012-03-16 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Open-close transition of MurA To be Published
4E7G	E. cloacae C115D/R120A MurA in the unliganded state 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2012-03-16 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Open-close transition of MurA To be Published
7TM6	Crystal structure of shikimate-3-phosphate and glyphosate bound 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, GLYPHOSATE, PENTAETHYLENE GLYCOL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-01-19 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Crystal structure of shikimate-3-phosphate and glyphosate bound 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae To be published
7TM5	Crystal structure of shikimate-3-phosphate bound 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-01-19 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal structure of shikimate-3-phosphate bound 3-phosphoshikimate 1-carboxyvinyltransferase from Klebsiella pneumoniae To be published

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