5M64
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![BU of 5m64 by Molmil](/molmil-images/mine/5m64) | RNA Polymerase I elongation complex with A49 tandem winged helix domain | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | 登録日 | 2016-10-24 | 公開日 | 2016-12-21 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
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6ND4
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![BU of 6nd4 by Molmil](/molmil-images/mine/6nd4) | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | 分子名称: | 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ... | 著者 | Hunziker, M, Barandun, J, Klinge, S. | 登録日 | 2018-12-13 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Elife, 8, 2019
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6UQK
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![BU of 6uqk by Molmil](/molmil-images/mine/6uqk) | Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide | 分子名称: | ZINC ION, inositol 1,4,5-triphosphate receptor, type 3 | 著者 | Azumaya, C.M, Linton, E.A, Risener, C.J, Nakagawa, T, Karakas, E. | 登録日 | 2019-10-20 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. J.Biol.Chem., 295, 2020
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3KGV
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6T3J
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![BU of 6t3j by Molmil](/molmil-images/mine/6t3j) | Dual Epitope Targeting by Anti-DR5 Antibodies | 分子名称: | IgG1-hDR5-01-Heavy Chain, IgG1-hDR5-01-Light Chain, IgG1-hDR5-05-Heavy Chain, ... | 著者 | Tauchert, M.J, Augustin, M, Krapp, S, Overdijk, M.B, Breij, E.C.W, Hibbert, R.G. | 登録日 | 2019-10-11 | 公開日 | 2020-09-16 | 最終更新日 | 2020-10-14 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism. Mol.Cancer Ther., 19, 2020
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7K17
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7KTS
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![BU of 7kts by Molmil](/molmil-images/mine/7kts) | Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) | 分子名称: | Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... | 著者 | Herbst, D.A, Esbin, M.N, Nogales, E. | 登録日 | 2020-11-24 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (19.09 Å) | 主引用文献 | Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
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6PV6
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![BU of 6pv6 by Molmil](/molmil-images/mine/6pv6) | Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2019-07-19 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
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1KAR
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![BU of 1kar by Molmil](/molmil-images/mine/1kar) | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR) | 分子名称: | HISTAMINE, Histidinol dehydrogenase, ZINC ION | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | 登録日 | 2001-11-02 | 公開日 | 2002-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1KAE
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![BU of 1kae by Molmil](/molmil-images/mine/1kae) | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Histidinol dehydrogenase, ... | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | 登録日 | 2001-11-01 | 公開日 | 2002-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1K75
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![BU of 1k75 by Molmil](/molmil-images/mine/1k75) | The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication. | 分子名称: | GLYCEROL, L-histidinol dehydrogenase, SULFATE ION | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2001-10-18 | 公開日 | 2002-02-27 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1KAH
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![BU of 1kah by Molmil](/molmil-images/mine/1kah) | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR) | 分子名称: | HISTIDINE, Histidinol dehydrogenase, ZINC ION | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | 登録日 | 2001-11-02 | 公開日 | 2002-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1DHP
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![BU of 1dhp by Molmil](/molmil-images/mine/1dhp) | DIHYDRODIPICOLINATE SYNTHASE | 分子名称: | DIHYDRODIPICOLINATE SYNTHASE, POTASSIUM ION | 著者 | Mirwaldt, C, Korndoerfer, I, Huber, R. | 登録日 | 1995-02-09 | 公開日 | 1997-02-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. J.Mol.Biol., 246, 1995
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1DU3
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![BU of 1du3 by Molmil](/molmil-images/mine/1du3) | Crystal structure of TRAIL-SDR5 | 分子名称: | DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND, ZINC ION | 著者 | Cha, S.-S, Sung, B.-J, Oh, B.-H. | 登録日 | 2000-01-14 | 公開日 | 2000-09-27 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity J.Biol.Chem., 275, 2000
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4NFM
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![BU of 4nfm by Molmil](/molmil-images/mine/4nfm) | Human tau tubulin kinase 1 (TTBK1) | 分子名称: | GLYCEROL, Tau-tubulin kinase 1 | 著者 | Sheriff, S. | 登録日 | 2013-10-31 | 公開日 | 2014-02-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor. Acta Crystallogr F Struct Biol Commun, 70, 2014
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5M5W
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![BU of 5m5w by Molmil](/molmil-images/mine/5m5w) | RNA Polymerase I open complex | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | 登録日 | 2016-10-23 | 公開日 | 2016-12-07 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
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6Z1P
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7TLR
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7TLM
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7TLQ
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6TPS
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5OA1
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![BU of 5oa1 by Molmil](/molmil-images/mine/5oa1) | RNA polymerase I pre-initiation complex | 分子名称: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ... | 著者 | Sadian, Y, Tafur, L, Kosinski, J, Jakobi, A.J, Muller, C.W. | 登録日 | 2017-06-20 | 公開日 | 2017-07-26 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into transcription initiation by yeast RNA polymerase I. EMBO J., 36, 2017
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4OD2
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5N5Y
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![BU of 5n5y by Molmil](/molmil-images/mine/5n5y) | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation III) | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | 登録日 | 2017-02-14 | 公開日 | 2017-04-05 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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5N5Z
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![BU of 5n5z by Molmil](/molmil-images/mine/5n5z) | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II) | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | 登録日 | 2017-02-14 | 公開日 | 2017-04-05 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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