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3FS3
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Crystal structure of malaria parasite Nucleosome Assembly Protein (NAP)
分子名称: Nucleosome assembly protein 1, putative
著者Gill, J, Yogavel, M, Kumar, A, Belrhali, H, Sharma, A.
登録日2009-01-09
公開日2009-01-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of malaria parasite nucleosome assembly protein: distinct modes of protein localization and histone recognition.
J.Biol.Chem., 284, 2009
2Z2R
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Nucleosome assembly proteins I (NAP-1, 74-365)
分子名称: Nucleosome assembly protein
著者Park, Y.J, Luger, K.
登録日2007-05-25
公開日2008-03-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1
J.Mol.Biol., 375, 2008
2AYU
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The structure of nucleosome assembly protein suggests a mechanism for histone binding and shuttling
分子名称: Nucleosome assembly protein
著者Park, Y.J, Luger, K.
登録日2005-09-08
公開日2006-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of nucleosome assembly protein 1.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3HFD
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Nucleosome Assembly Protein 1 from Plasmodium knowlesi
分子名称: Nucleosome assembly protein 1
著者Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2009-05-11
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nucleosome Assembly Protein 1 from Plasmodium knowlesi
To be Published
8PQQ
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Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine
分子名称: 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, MAGNESIUM ION, Nucleoside 2-deoxyribosyltransferase
著者Tang, P, Harding, C.J, Czekster, M.C.
登録日2023-07-11
公開日2024-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
8PQR
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Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to DAD_Immucillin-H
分子名称: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Nucleoside 2-deoxyribosyltransferase
著者Tang, P, Harding, C.J, Czekster, C.M.
登録日2023-07-11
公開日2024-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.586 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
8PQT
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Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Bis-Tris
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleoside 2-deoxyribosyltransferase
著者Tang, P, Harding, C.J, Czekster, C.M.
登録日2023-07-11
公開日2024-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
8PQP
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Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 D62N Mutant bound to ImmH-Forodesine
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, Nucleoside 2-deoxyribosyltransferase
著者Tang, P, Harding, C.J, Czekster, M.C.
登録日2023-07-11
公開日2024-02-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.709 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
1V48
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Calf spleen purine nucleoside phosphorylase (PNP) binary complex with 9-(5,5-difluoro-5-phosphonopenthyl)guanine
分子名称: 9-(5,5-DIFLUORO-5-PHOSPHONOPENTYL)GUANINE, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Luic, M, Koellner, G, Yokomatsu, T, Shibuya, S, Bzowska, A.
登録日2003-11-11
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
Acta Crystallogr.,Sect.D, 60, 2004
4DZ6
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Transition state mimic of nucleoside-diphosphate kinase from borrelia burgdorferi with bound vanadate and adp
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-02-29
公開日2012-03-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties.
Acta Crystallogr F Struct Biol Commun, 74, 2018
1KIE
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Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine
分子名称: 3-DEAZA-ADENOSINE, CALCIUM ION, NICKEL (II) ION, ...
著者Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J.
登録日2001-12-03
公開日2002-05-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
J.Biol.Chem., 277, 2002
4VHB
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THIOCYANATE ADDUCT OF THE BACTERIAL HEMOGLOBIN FROM VITREOSCILLA SP.
分子名称: PROTEIN (HEMOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
著者Bolognesi, M, Boffi, A, Coletta, M, Mozzarelli, A, Pesce, A, Tarricone, C, Ascenzi, P.
登録日1999-03-11
公開日1999-08-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Anticooperative ligand binding properties of recombinant ferric Vitreoscilla homodimeric hemoglobin: a thermodynamic, kinetic and X-ray crystallographic study.
J.Mol.Biol., 291, 1999
6RYR
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Nucleosome-CHD4 complex structure (single CHD4 copy)
分子名称: Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ...
著者Farnung, L, Ochmann, M, Cramer, P.
登録日2019-06-11
公開日2020-07-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
6RYU
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Nucleosome-CHD4 complex structure (two CHD4 copies)
分子名称: Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ...
著者Farnung, L, Ochmann, M, Cramer, P.
登録日2019-06-12
公開日2020-07-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
2OXT
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Crystal structure of Meaban virus nucleoside-2'-O-methyltransferase
分子名称: NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
著者Mastrangelo, E, Milani, M, Bollati, M, Bolognesi, M.
登録日2007-02-21
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase
Protein Sci., 16, 2007
1KIC
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Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with inosine
分子名称: CALCIUM ION, INOSINE, NICKEL (II) ION, ...
著者Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J.
登録日2001-12-03
公開日2002-05-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
J.Biol.Chem., 277, 2002
2FF2
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Crystal structure of Trypanosoma vivax nucleoside hydrolase co-crystallized with ImmucillinH
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase, ...
著者Versees, W, Barlow, J, Steyaert, J.
登録日2005-12-18
公開日2006-05-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
J.Mol.Biol., 359, 2006
2FF1
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Crystal structure of Trypanosoma vivax nucleoside hydrolase soaked with ImmucillinH
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase
著者Versees, W, Barlow, J, Steyaert, J.
登録日2005-12-18
公開日2006-05-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
J.Mol.Biol., 359, 2006
1J90
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Crystal Structure of Drosophila Deoxyribonucleoside Kinase
分子名称: 2'-DEOXYCYTIDINE, Deoxyribonucleoside kinase, SULFATE ION
著者Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H.
登録日2001-05-23
公開日2001-11-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
4JEP
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Crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)
分子名称: Nucleoside-triphosphatase 2
著者Krug, U, Totzauer, R, Strater, N.
登録日2013-02-27
公開日2013-04-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 represents a conformational intermediate in the reductive activation mechanism of the tetrameric enzyme.
Proteins, 81, 2013
4A5B
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Crystal structure of the C258S/C268S variant of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)
分子名称: NUCLEOSIDE-TRIPHOSPHATASE 2
著者Krug, U, Zebisch, M, Strater, N.
登録日2011-10-24
公開日2011-11-30
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural Insight Into Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
J.Biol.Chem., 287, 2012
5XF3
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF5
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration)
分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF4
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration)
分子名称: (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
3NGS
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Structure of Leishmania nucleoside diphosphate kinase b with ordered nucleotide-binding loop
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Nucleoside diphosphate kinase, PHOSPHATE ION
著者Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T.
登録日2010-06-13
公開日2011-04-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011

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