3MYE
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4OVU
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![BU of 4ovu by Molmil](/molmil-images/mine/4ovu) | Crystal Structure of p110alpha in complex with niSH2 of p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. | 登録日 | 2014-01-14 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
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1OZS
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4B2T
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![BU of 4b2t by Molmil](/molmil-images/mine/4b2t) | The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning | 分子名称: | T-COMPLEX PROTEIN 1 SUBUNIT ALPHA, T-COMPLEX PROTEIN 1 SUBUNIT BETA, T-COMPLEX PROTEIN 1 SUBUNIT DELTA, ... | 著者 | Kalisman, N, Schroeder, G.F, Levitt, M. | 登録日 | 2012-07-17 | 公開日 | 2013-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | 主引用文献 | The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning Structure, 21, 2013
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2ROT
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![BU of 2rot by Molmil](/molmil-images/mine/2rot) | Structure of chimeric variant of SH3 domain- SHH | 分子名称: | Spectrin alpha chain, brain | 著者 | Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. | 登録日 | 2008-04-10 | 公開日 | 2009-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs". Biochim.Biophys.Acta, 1794, 2009
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4JPS
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![BU of 4jps by Molmil](/molmil-images/mine/4jps) | Co-crystal Structures of the Lipid Kinase PI3K alpha with Pan and Isoform Selective Inhibitors | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | 著者 | Knapp, M.S, Elling, R.A. | 登録日 | 2013-03-19 | 公開日 | 2014-04-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation. Bioorg.Med.Chem.Lett., 23, 2013
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1UN4
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4AE3
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![BU of 4ae3 by Molmil](/molmil-images/mine/4ae3) | Crystal structure of ammosamide 272:myosin-2 motor domain complex | 分子名称: | 1,2-ETHANEDIOL, ADP ORTHOVANADATE, AMMOSAMIDE 272, ... | 著者 | Chinthalapudi, K, Heissler, S.M, Fenical, W, Manstein, D.J. | 登録日 | 2012-01-05 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Ammosamide Mediated Myosin Motor Activity Inhibition To be Published
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4P7I
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4L23
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![BU of 4l23 by Molmil](/molmil-images/mine/4l23) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha and PI-103 | 分子名称: | 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | 著者 | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | 登録日 | 2013-06-04 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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1UN3
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5BNH
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![BU of 5bnh by Molmil](/molmil-images/mine/5bnh) | Crystal structure of the HLTF HIRAN domain with a ssDNA fragment | 分子名称: | ACETATE ION, DNA (5'-D(*(GD)P*GP*TP*G)-3'), DNA (5'-D(*(TD)P*TP*G)-3'), ... | 著者 | Neculai, D, Walker, J.R, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S. | 登録日 | 2015-05-26 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Co-crystal structure of the HLTF HIRAN domain with a ssDNA fragment To Be Published
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4OVV
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![BU of 4ovv by Molmil](/molmil-images/mine/4ovv) | Crystal Structure of PI3Kalpha in complex with diC4-PIP2 | 分子名称: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, PHOSPHATE ION, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | 著者 | Gabelli, S.B, Vogelstein, B, Miller, M, Amzel, L.M. | 登録日 | 2014-01-14 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
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4L2Y
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![BU of 4l2y by Molmil](/molmil-images/mine/4l2y) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha and compound 9d | 分子名称: | 3-amino-5-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | 著者 | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | 登録日 | 2013-06-05 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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4L1B
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![BU of 4l1b by Molmil](/molmil-images/mine/4l1b) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION | 著者 | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | 登録日 | 2013-06-03 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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2RMO
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![BU of 2rmo by Molmil](/molmil-images/mine/2rmo) | Solution structure of alpha-spectrin_SH3-bergerac from Chicken | 分子名称: | Spectrin alpha chain, brain | 著者 | Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. | 登録日 | 2007-11-07 | 公開日 | 2008-09-30 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy Russ.J.Bioorganic Chem., 34, 2008
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4C6A
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![BU of 4c6a by Molmil](/molmil-images/mine/4c6a) | High Resolution Structure of the Nucleoside diphosphate kinase | 分子名称: | DI(HYDROXYETHYL)ETHER, NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC | 著者 | Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B. | 登録日 | 2013-09-18 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. Antiviral Res., 117, 2015
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2ASE
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4CP5
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![BU of 4cp5 by Molmil](/molmil-images/mine/4cp5) | ndpK in complex with (Rp)-SPMPApp | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-sulfanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B. | 登録日 | 2014-01-31 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. Antiviral Res., 117, 2015
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1MMD
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![BU of 1mmd by Molmil](/molmil-images/mine/1mmd) | TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Fisher, A.J, Holden, H.M, Rayment, I. | 登録日 | 1995-03-21 | 公開日 | 1996-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry, 34, 1995
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5BY9
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1WYN
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![BU of 1wyn by Molmil](/molmil-images/mine/1wyn) | Solution structure of the CH domain of human calponin-2 | 分子名称: | Calponin-2 | 著者 | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-02-15 | 公開日 | 2005-08-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the CH domain of human calponin-2 To be Published
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1NF3
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![BU of 1nf3 by Molmil](/molmil-images/mine/1nf3) | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 | 分子名称: | G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... | 著者 | Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. | 登録日 | 2002-12-12 | 公開日 | 2003-03-04 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003
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1W8J
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2BJQ
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![BU of 2bjq by Molmil](/molmil-images/mine/2bjq) | Crystal structure of the nematode sperm cell motility protein MFP2 | 分子名称: | MFP2A | 著者 | Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M. | 登録日 | 2005-02-07 | 公開日 | 2005-03-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility J.Mol.Biol., 347, 2005
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