PDB: 35832 件ウェブページステータス検索Chemie searchBIRD

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3MYE	Crystal Structure of HP67 L61GL 分子名称: Villin-1 著者 Brown, J.W, Farelli, J.D, McKnight, C.J. 登録日 2010-05-10 公開日 2011-05-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Conserving the Hydrophobic Core at the Expense of Backbone Conformation in Villin Headpiece To be Published
4OVU	Crystal Structure of p110alpha in complex with niSH2 of p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. 登録日 2014-01-14 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
1OZS	C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I 分子名称: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... 著者 Lindhout, D.A, Sykes, B.D. 登録日 2003-04-09 公開日 2003-09-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I. J.Biol.Chem., 278, 2003
4B2T	The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning 分子名称: T-COMPLEX PROTEIN 1 SUBUNIT ALPHA, T-COMPLEX PROTEIN 1 SUBUNIT BETA, T-COMPLEX PROTEIN 1 SUBUNIT DELTA, ... 著者 Kalisman, N, Schroeder, G.F, Levitt, M. 登録日 2012-07-17 公開日 2013-03-20 最終更新日 2019-11-06 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning Structure, 21, 2013
2ROT	Structure of chimeric variant of SH3 domain- SHH 分子名称: Spectrin alpha chain, brain 著者 Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. 登録日 2008-04-10 公開日 2009-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs". Biochim.Biophys.Acta, 1794, 2009
4JPS	Co-crystal Structures of the Lipid Kinase PI3K alpha with Pan and Isoform Selective Inhibitors 分子名称: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... 著者 Knapp, M.S, Elling, R.A. 登録日 2013-03-19 公開日 2014-04-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation. Bioorg.Med.Chem.Lett., 23, 2013
1UN4	CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T80A 分子名称: ANGIOGENIN, CITRIC ACID 著者 Holloway, D.E, Chavali, G.B, Acharya, K.R. 登録日 2003-09-04 公開日 2004-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41 Biochemistry, 43, 2004
4AE3	Crystal structure of ammosamide 272:myosin-2 motor domain complex 分子名称: 1,2-ETHANEDIOL, ADP ORTHOVANADATE, AMMOSAMIDE 272, ... 著者 Chinthalapudi, K, Heissler, S.M, Fenical, W, Manstein, D.J. 登録日 2012-01-05 公開日 2013-01-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Ammosamide Mediated Myosin Motor Activity Inhibition To be Published
4P7I	Crystal structure of the Merlin FERM/DCAF1 complex 分子名称: GLYCEROL, Merlin, Protein VPRBP 著者 Wei, Z, Li, Y, Zhang, M. 登録日 2014-03-27 公開日 2014-04-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1. J.Biol.Chem., 289, 2014
4L23	Crystal Structure of p110alpha complexed with niSH2 of p85alpha and PI-103 分子名称: 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-04 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
1UN3	CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T44D 分子名称: ANGIOGENIN 著者 Holloway, D.E, Chavali, G.B, Acharya, K.R. 登録日 2003-09-04 公開日 2004-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41 Biochemistry, 43, 2004
5BNH	Crystal structure of the HLTF HIRAN domain with a ssDNA fragment 分子名称: ACETATE ION, DNA (5'-D(*(GD)P*GP*TP*G)-3'), DNA (5'-D(*(TD)P*TP*G)-3'), ... 著者 Neculai, D, Walker, J.R, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S. 登録日 2015-05-26 公開日 2016-05-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Co-crystal structure of the HLTF HIRAN domain with a ssDNA fragment To Be Published
4OVV	Crystal Structure of PI3Kalpha in complex with diC4-PIP2 分子名称: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, PHOSPHATE ION, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... 著者 Gabelli, S.B, Vogelstein, B, Miller, M, Amzel, L.M. 登録日 2014-01-14 公開日 2014-09-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
4L2Y	Crystal Structure of p110alpha complexed with niSH2 of p85alpha and compound 9d 分子名称: 3-amino-5-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-05 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
4L1B	Crystal Structure of p110alpha complexed with niSH2 of p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-03 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.586 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
2RMO	Solution structure of alpha-spectrin_SH3-bergerac from Chicken 分子名称: Spectrin alpha chain, brain 著者 Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. 登録日 2007-11-07 公開日 2008-09-30 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy Russ.J.Bioorganic Chem., 34, 2008
4C6A	High Resolution Structure of the Nucleoside diphosphate kinase 分子名称: DI(HYDROXYETHYL)ETHER, NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC 著者 Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B. 登録日 2013-09-18 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. Antiviral Res., 117, 2015
2ASE	NMR structure of the F28L mutant of Cdc42Hs 分子名称: Cell division control protein 42 homolog 著者 Adams, P.D, Oswald, R.E. 登録日 2005-08-23 公開日 2006-02-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of an Oncogenic Mutant of Cdc42Hs Biochemistry, 45, 2006
4CP5	ndpK in complex with (Rp)-SPMPApp 分子名称: NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-sulfanyl-phosphoryl] phosphono hydrogen phosphate 著者 Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B. 登録日 2014-01-31 公開日 2015-02-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. Antiviral Res., 117, 2015
1MMD	TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Fisher, A.J, Holden, H.M, Rayment, I. 登録日 1995-03-21 公開日 1996-08-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry, 34, 1995
5BY9	The crystal structure of polyglycilated 14-3-3 protein from Giardia intestinalis 分子名称: 14-3-3 protein 著者 Fiorillo, A, Ilari, A, Lalle, M. 登録日 2015-06-10 公開日 2016-04-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions. J.Chem.Inf.Model., 55, 2015
1WYN	Solution structure of the CH domain of human calponin-2 分子名称: Calponin-2 著者 Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-02-15 公開日 2005-08-15 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the CH domain of human calponin-2 To be Published
1NF3	Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 分子名称: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... 著者 Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. 登録日 2002-12-12 公開日 2003-03-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003
1W8J	Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free 分子名称: MYOSIN VA, SULFATE ION 著者 Coureux, P.-D, Sweeney, H.L, Houdusse, A. 登録日 2004-09-22 公開日 2005-02-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction Embo J., 23, 2004
2BJQ	Crystal structure of the nematode sperm cell motility protein MFP2 分子名称: MFP2A 著者 Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M. 登録日 2005-02-07 公開日 2005-03-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility J.Mol.Biol., 347, 2005

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