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5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
分子名称: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
2P4X
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Crystal Structure of Atp12 from Paracoccus Denitrificans
分子名称: ATP12 ATPase
著者Ludlam, A.V, Brunzelle, J.S, Gatti, D.L, Ackerman, S.H.
登録日2007-03-13
公開日2008-03-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Atp12 from Paracoccus Denitrificans
To be Published
6LFG
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BU of 6lfg by Molmil
Cryo-EM structure of the Drosophila CTP synthase product-bound filament
分子名称: CTP synthase
著者Ji-long, L, Xian, Z, Chen-Jun, G.
登録日2019-12-02
公開日2020-03-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.58 Å)
主引用文献Drosophila CTP synthase can form distinct substrate- and product-bound filaments.
J Genet Genomics, 46, 2019
1A48
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SAICAR SYNTHASE
分子名称: PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, SULFATE ION
著者Levdikov, V.M, Melik-Adamyan, W.R, Lamzin, V.S, Wilson, K.S.
登録日1998-02-12
公開日1999-03-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis.
Structure, 6, 1998
5U05
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Cryo-EM structure of the E. coli CTP synthase tetramer
分子名称: CTP synthase
著者Lynch, E.M, Hicks, D.R, Kollman, J.M.
登録日2016-11-22
公開日2017-04-26
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
6L6Z
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BU of 6l6z by Molmil
Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament
分子名称: CTP synthase
著者Ji-Long, L, Xian, Z, Chen-Jun, G.
登録日2019-10-30
公開日2020-03-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.09 Å)
主引用文献Drosophila CTP synthase can form distinct substrate- and product-bound filaments.
J Genet Genomics, 46, 2019
2IWZ
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BU of 2iwz by Molmil
Human mitochondrial beta-ketoacyl ACP synthase complexed with hexanoic acid
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, AMMONIUM ION, HEXANOIC ACID
著者Christensen, C.E, Kragelund, B.B, von Wettstein-Knowles, P, Henriksen, A.
登録日2006-07-05
公開日2007-02-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase.
Protein Sci., 16, 2007
4UTQ
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A structural model of the active ribosome-bound membrane protein insertase YidC
分子名称: ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC
著者Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R.
登録日2014-07-22
公開日2014-07-30
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc.
Elife, 3, 2014
9COP
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BU of 9cop by Molmil
Yeast RAVE bound to V-ATPase V1 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Regulator of V-ATPase in vacuolar membrane protein 1, ...
著者Wang, H, Rubinstein, J.L.
登録日2024-07-17
公開日2024-11-20
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structure of yeast RAVE bound to a partial V 1 complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
6Y87
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Crystal Structure of the Homospermidine Synthase (HSS) from Pseudomonas aeruginosa in Complex with NAD and PUT
分子名称: 1,4-DIAMINOBUTANE, Homospermidine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Helfrich, F, Scheidig, A.J.
登録日2020-03-03
公開日2021-03-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and catalytic characterization of Blastochloris viridis and Pseudomonas aeruginosa homospermidine synthases supports the essential role of cation-pi interaction.
Acta Crystallogr D Struct Biol, 77, 2021
7FUR
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BU of 7fur by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
分子名称: 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ...
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7Z15
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E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ...
著者Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
登録日2022-02-24
公開日2022-06-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (1.93 Å)
主引用文献Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
2IWY
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Human mitochondrial beta-ketoacyl ACP synthase
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, AMMONIUM ION
著者Christensen, C.E, Kragelund, B.B, von Wettstein-Knowles, P, Henriksen, A.
登録日2006-07-05
公開日2007-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase.
Protein Sci., 16, 2007
1O9T
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Methionine adenosyltransferase complexed with both substrates ATP and methionine
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, METHIONINE, ...
著者Gonzalez, B, Pajares, M.A, Hermoso, J.A, Sanz-Aparicio, J.
登録日2002-12-18
公開日2003-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
4WQ5
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YgjD(V85E)-YeaZ heterodimer in complex with ATP
分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ...
著者Zhang, W.
登録日2014-10-21
公開日2015-01-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
4WQ4
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BU of 4wq4 by Molmil
E. coli YgjD(E12A)-YeaZ heterodimer in complex with ATP
分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Zhang, W, Collinet, B.
登録日2014-10-21
公開日2015-01-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
1O93
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Methionine Adenosyltransferase complexed with ATP and a L-methionine analogue
分子名称: (2S,4S)-2-AMINO-4,5-EPOXIPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Gonzalez, B, Pajares, M.A, Hermoso, J.A, Sanz-Aparicio, J.
登録日2002-12-10
公開日2003-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
6QFB
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BU of 6qfb by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2019-01-09
公開日2019-04-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6NJO
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Structure of the assembled ATPase EscN from the enteropathogenic E. coli (EPEC) type III secretion system
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J.
登録日2019-01-03
公開日2019-02-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
6NJP
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Structure of the assembled ATPase EscN in complex with its central stalk EscO from the enteropathogenic E. coli (EPEC) type III secretion system
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, EscO, ...
著者Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J.
登録日2019-01-03
公開日2019-02-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
7FUJ
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BU of 7fuj by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-2-cyano-N-[4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide
分子名称: (2Z)-2-cyano-N-[(4P)-4-(3-fluorophenyl)-5-(methanesulfonyl)pyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
1J3N
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Crystal Structure of 3-oxoacyl-(acyl-carrier protein) Synthase II from Thermus thermophilus HB8
分子名称: 3-oxoacyl-(acyl-carrier protein) synthase II, CITRIC ACID, MAGNESIUM ION
著者Bagautdinov, B, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-02-10
公開日2003-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of 3-oxoacyl-(acyl-carrier protein) synthase II from Thermus thermophilus HB8.
Acta Crystallogr.,Sect.F, 64, 2008
7FDE
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CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1
分子名称: Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
登録日2021-07-16
公開日2021-12-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
3F7Z
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X-ray Co-Crystal Structure of Glycogen Synthase Kinase 3beta in Complex with an Inhibitor
分子名称: 2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole, Glycogen synthase kinase-3 beta
著者Mol, C.D, Dougan, D.R.
登録日2008-11-10
公開日2009-03-10
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design, synthesis and structure-activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta.
Bioorg.Med.Chem., 17, 2009

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件を2025-07-09に公開中

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