7FUR
Crystal Structure of human cyclic GMP-AMP synthase in complex with 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
Summary for 7FUR
| Entry DOI | 10.2210/pdb7fur/pdb |
| Group deposition | To be published (G_1002263) |
| Descriptor | Cyclic GMP-AMP synthase, ZINC ION, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | immune response, transferase, ntase, dna sensor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43417.36 |
| Authors | Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21) |
| Primary citation | Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G. Crystal Structure of a human cyclic GMP-AMP synthase complex To be published, |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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