PDB: 48369 件ウェブページステータス検索Chemie searchBIRD

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5ICM	17beta-hydroxysteroid dehydrogenase type 14 in complex with a non-steroidal inhibitor 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... 著者 Bertoletti, N, Braun, F, Marchais-Oberwinkler, S, Heine, A, Klebe, G. 登録日 2016-02-23 公開日 2016-07-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59, 2016
2OJ4	Crystal structure of RGS3 RGS domain 分子名称: Regulator of G-protein signaling 3 著者 Boura, E, Obsil, T. 登録日 2007-01-12 公開日 2007-01-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3). J.Struct.Biol., 170, 2010
5JSF	Crystal structure of 17beta-hydroxysteroid dehydrogenase 14 S205 variant in complex with NAD. 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. 登録日 2016-05-08 公開日 2016-07-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.842 Å) 主引用文献 New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59, 2016
5JS6	Crystal structure of 17beta-hydroxysteroid dehydrogenase 14 T205 variant in complex with NAD. 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. 登録日 2016-05-07 公開日 2016-07-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59, 2016
2XWY	Structure of MK-3281, a Potent Non-Nucleoside Finger-Loop Inhibitor, in complex with the Hepatitis C Virus NS5B Polymerase 分子名称: (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Di Marco, S, Baiocco, P. 登録日 2010-11-06 公開日 2010-12-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Discovery of (7R)-14-Cyclohexyl-7-{[2-(Dimethylamino)Ethyl] (Methyl)Amino}-7,8-Dihydro-6H-Indolo[1,2-E][1,5] Benzoxazocine -11-Carboxylic Acid (Mk-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus Ns5B Polymerase J.Med.Chem., 54, 2011
4G3J	Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the VNI derivative (R)-N-(1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide [R-VNI-triazole (VNT)] 分子名称: N-[(1R)-1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, sterol 14-alpha-demethylase 著者 Hargrove, T.Y, Wawrzak, Z, Waterman, M.R, Lepesheva, G.I. 登録日 2012-07-14 公開日 2013-07-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis. J Infect Dis, 212, 2015
4G7G	Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the VNI derivative (R)-N-(1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide [VNI/VNF (VFV)] 分子名称: N-[(1R)-1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, sterol 14-alpha-demethylase 著者 Hargrove, T.Y, Wawrzak, Z, Waterman, M.R, Lepesheva, G.I. 登録日 2012-07-20 公開日 2013-07-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis. J Infect Dis, 212, 2015
6Y8A	14-3-3 Sigma in complex with phosphorylated camkk2{pS511} peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-03-04 公開日 2020-10-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y8D	14-3-3 Sigma in complex with phosphorylated caspase{pS164} peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-03-04 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y3R	14-3-3 Sigma in complex with phosphorylated (Thr391) Gab2 peptide 分子名称: 14-3-3 protein sigma, Chain P, MAGNESIUM ION 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-18 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y8B	14-3-3 Sigma in complex with phosphorylated caspase{pS139} peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-03-04 公開日 2020-10-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y3M	14-3-3 Sigma in complex with phosphorylated ATPase peptide 分子名称: 14-3-3 protein sigma, ATPase peptide, CALCIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-18 公開日 2020-10-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y8E	14-3-3 Sigma in complex with phosphorylated MLF1 peptide 分子名称: 14-3-3 protein sigma, ARG-SER-PHE-SEP-GLU-PRO-PHE-GLY, CALCIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-03-04 公開日 2020-10-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y40	14-3-3 Sigma in complex with phosphorylated PLN peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-19 公開日 2020-10-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y3S	14-3-3 Sigma in complex with phosphorylated (pS210) Gab2 peptide 分子名称: 14-3-3 protein sigma, Gab2, MAGNESIUM ION 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-18 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y3V	14-3-3 Sigma in complex with phosphorylated c-Jun peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-19 公開日 2020-10-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y44	14-3-3 Sigma in complex with phosphorylated SOS1 peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-19 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6Y3O	14-3-3 Sigma in complex with phosphorylated CAMKK2 peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CAMKK2, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-18 公開日 2020-10-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
5GMT	Crystal structure of the marine PL-14 alginate lyase from Aplysia kurodai 分子名称: Alginate lyase 著者 Qin, H.-M, Miyakawa, T, Nakamura, A, Tanokura, M. 登録日 2016-07-16 公開日 2017-01-04 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structure and Polymannuronate Specificity of a Eukaryotic Member of Polysaccharide Lyase Family 14. J. Biol. Chem., 292, 2017
4C3I	Structure of 14-subunit RNA polymerase I at 3.0 A resolution, crystal form C2-100 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
6Z5S	RC-LH1(14)-W complex from Rhodopseudomonas palustris 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, (6~{R},10~{S},14~{R},19~{R},23~{S},24~{E},27~{S},28~{E})-2,6,10,14,19,23,27,31-octamethyldotriaconta-24,28-dien-2-ol, ... 著者 Swainsbury, D.J.K, Qian, P, Hitchcock, A, Hunter, C.N. 登録日 2020-05-27 公開日 2021-01-13 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels. Sci Adv, 7, 2021
5ULO	Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta, TBC1 domain family member 7 peptide, ... 著者 DONG, A, HU, J, MADIGAN, J, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) 登録日 2017-01-25 公開日 2018-01-31 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide to be published
4C3H	Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
4C3J	Structure of 14-subunit RNA polymerase I at 3.35 A resolution, crystal form C2-90 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
2ZVT	Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2 分子名称: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma 著者 Waku, T, Oyama, T, Shiraki, T, Morikawa, K. 登録日 2008-11-19 公開日 2009-10-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands Febs Lett., 583, 2009

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