PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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1NF3	Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 分子名称: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... 著者 Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. 登録日 2002-12-12 公開日 2003-03-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003
1B4S	STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE H122G MUTANT 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE, ... 著者 Meyer, P, Janin, J. 登録日 1998-12-28 公開日 1999-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nucleophilic activation by positioning in phosphoryl transfer catalyzed by nucleoside diphosphate kinase. Biochemistry, 38, 1999
7PKN	Structure of the human CCAN deltaCT complex 分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ... 著者 Muir, K.W, Yatskevich, S, Bellini, D, Barford, D. 登録日 2021-08-25 公開日 2022-04-27 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
1BUX	3'-PHOSPHORYLATED NUCLEOTIDES BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE 分子名称: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, NUCLEOSIDE DIPHOSPHATE KINASE 著者 Xu, Y, Schneider, B, Deville-Bonne, D, Veron, M, Janin, J. 登録日 1998-09-07 公開日 1999-04-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 3'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activity. J.Biol.Chem., 273, 1998
1AGI	CRYSTAL STRUCTURE OF BOVINE ANGIOGENIN AT 1.5 ANGSTROMS RESOLUTION 分子名称: ANGIOGENIN 著者 Acharya, K.R, Shapiro, R, Riordan, J.F, Vallee, B.L. 登録日 1995-01-06 公開日 1996-04-03 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of bovine angiogenin at 1.5-A resolution. Proc.Natl.Acad.Sci.USA, 92, 1995
7QOO	Structure of the human inner kinetochore CCAN complex 分子名称: Centromere protein C, Centromere protein H, Centromere protein I, ... 著者 Vetter, I.R, Pesenti, M, Raisch, T. 登録日 2021-12-24 公開日 2022-06-08 最終更新日 2022-06-15 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization. Mol.Cell, 82, 2022
6R3V	Crystal Structure of RhoA-GDP-Pi in Complex with RhoGAP 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Jin, Y. 登録日 2019-03-21 公開日 2019-05-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A GAP-GTPase-GDP-PiIntermediate Crystal Structure Analyzed by DFT Shows GTP Hydrolysis Involves Serial Proton Transfers. Chemistry, 25, 2019
1CD9	2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR) 著者 Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K. 登録日 1999-03-08 公開日 2000-03-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature, 401, 1999
1AIN	CRYSTAL STRUCTURE OF HUMAN ANNEXIN I AT 2.5 ANGSTROMS RESOLUTION 分子名称: ANNEXIN I, CALCIUM ION 著者 Kim, S.-H. 登録日 1992-06-03 公開日 1993-07-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human annexin I at 2.5 A resolution. Protein Sci., 2, 1993
1B99	3'-FLUORO-URIDINE DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE 分子名称: 2',3'-DIDEOXY-3'-FLUORO-URIDIDINE-5'-DIPHOSPHATE, PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), PYROPHOSPHATE 2- 著者 Janin, J, Xu, Y. 登録日 1999-02-22 公開日 1999-06-28 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Catalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography. Biochemistry, 38, 1999
3GCG	crystal structure of MAP and CDC42 complex 分子名称: Cell division control protein 42 homolog, L0028 (Mitochondria associated protein) 著者 Chai, J, Huang, Z, Feng, Y, Wu, X. 登録日 2009-02-22 公開日 2009-07-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics Nat.Struct.Mol.Biol., 16, 2009
8ETD	Crystal Structure of Schizosaccharomyces pombe Rho1 分子名称: GTP-binding protein rho1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Huang, Q, Xie, J, Seetharaman, J. 登録日 2022-10-16 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal Structure of Schizosaccharomyces pombe Rho1 Reveals Its Evolutionary Relationship with Other Rho GTPases. Biology (Basel), 11, 2022
8ERA	RMC-5552 in complex with mTORC1 and FKBP12 分子名称: (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, 1-[6-{[(3M)-4-amino-3-(2-amino-1,3-benzoxazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-3,4-dihydroisoquinolin-2(1H)-yl]-3-hydroxypropan-1-one, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... 著者 Tomlinson, A.C.A, Yano, J.K. 登録日 2022-10-11 公開日 2022-12-28 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors. J.Med.Chem., 66, 2023
6L1U	Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril 分子名称: Alpha-synuclein 著者 Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y. 登録日 2019-09-30 公開日 2020-08-12 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
6R9H	Crystal structure of the PDZ tandem of syntenin in complex with fragment C58 分子名称: (2~{S})-2-[2-(4-chlorophenyl)sulfanylethanoylamino]-3-methyl-butanoic acid, ACETATE ION, PHOSPHATE ION, ... 著者 Feracci, M, Barral, K. 登録日 2019-04-03 公開日 2021-02-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loadifing with syndecan and EpCAM cargo. J Extracell Vesicles, 10, 2020
1MYO	SOLUTION STRUCTURE OF MYOTROPHIN, NMR, 44 STRUCTURES 分子名称: MYOTROPHIN 著者 Yang, Y, Nanduri, S, Sen, S, Qin, J. 登録日 1998-08-17 公開日 1999-08-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin. Structure, 6, 1998
6KZ1	Complex structure of Whirlin and Myosin XVa 分子名称: Myosin XVa, Whirlin 著者 Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. 登録日 2019-09-22 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
3LVR	The crystal structure of ASAP3 in complex with Arf6 in transition state soaked with Calcium 分子名称: ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ... 著者 Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A. 登録日 2010-02-22 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism Cell(Cambridge,Mass.), 141, 2010
3LYQ	Crystal structure of IpgB2 from Shigella flexneri 分子名称: CITRATE ANION, IpgB2, MU-OXO-DIIRON 著者 Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. 登録日 2010-02-28 公開日 2010-03-31 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
6M67	The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation 分子名称: Pannexin-1 著者 Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. 登録日 2020-03-13 公開日 2020-04-15 最終更新日 2020-05-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
6LRQ	Cryo-EM structure of A53T alpha-synuclein amyloid fibril 分子名称: Alpha-synuclein 著者 Sun, Y.P, Zhao, K, Liu, C. 登録日 2020-01-16 公開日 2020-04-08 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Cryo-EM structure of full-length alpha-synuclein amyloid fibril with Parkinson's disease familial A53T mutation. Cell Res., 30, 2020
6LTO	cryo-EM structure of full length human Pannexin1 分子名称: Pannexin-1 著者 Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. 登録日 2020-01-23 公開日 2020-05-13 最終更新日 2020-05-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for gating mechanism of Pannexin 1 channel. Cell Res., 30, 2020
6M68	The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX 分子名称: Pannexin-1 著者 Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. 登録日 2020-03-13 公開日 2020-04-15 最終更新日 2020-05-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
6M66	The Cryo-EM Structure of Human Pannexin 1 分子名称: Pannexin-1 著者 Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. 登録日 2020-03-13 公開日 2020-04-15 最終更新日 2020-05-13 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
4L1B	Crystal Structure of p110alpha complexed with niSH2 of p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-03 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.586 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014

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