PDB: 82686 件ウェブページステータス検索Chemie searchBIRD

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8B6S	X-ray structure of the haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG1) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate 分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein,Haloalkane dehalogenase, ... 著者 Tarnawski, M, Hellweg, L, Hiblot, J. 登録日 2022-09-27 公開日 2023-07-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19, 2023
8B6R	X-ray structure of the haloalkane dehalogenase HaloTag7 labeled with a chloroalkane Cyanine3 fluorophore substrate 分子名称: CHLORIDE ION, GLYCEROL, Haloalkane dehalogenase, ... 著者 Tarnawski, M, Hellweg, L, Hiblot, J. 登録日 2022-09-27 公開日 2023-07-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19, 2023
8B6M	Tankyrase 2 in complex with an inhibitor 分子名称: GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, SULFATE ION, ... 著者 Bosetti, C, Sowa, S.T, Lehtio, L. 登録日 2022-09-27 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Tankyrase 2 in complex with an inhibitor To Be Published
8B6J	Cryo-EM structure of cytochrome bc1 complex (complex-III) from respiratory supercomplex of Tetrahymena thermophila 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apocytochrome b, ... 著者 Muhleip, A, Kock Flygaard, R, Amunts, A. 登録日 2022-09-27 公開日 2023-03-29 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex. Nature, 615, 2023
8B6I	KRasG12C ligand complex 分子名称: 1-[(4~{a}~{S})-7-chloranyl-8-(5-methyl-2~{H}-indazol-4-yl)-1,2,4,4~{a},5,11-hexahydropyrazino[2,1-c][1,4]benzoxazepin-3-yl]propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Phillips, C, Breed, J. 登録日 2022-09-27 公開日 2023-07-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS G12C with Demonstrable CNS Penetration. J.Med.Chem., 66, 2023
8B6H	Cryo-EM structure of cytochrome c oxidase dimer (complex IV) from respiratory supercomplex of Tetrahymena thermophila 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ... 著者 Muhleip, A, Kock Flygaard, R, Amunts, A. 登録日 2022-09-27 公開日 2023-03-29 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex. Nature, 615, 2023
8B6G	Cryo-EM structure of succinate dehydrogenase complex (complex-II) in respiratory supercomplex of Tetrahymena thermophila 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, ... 著者 Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A. 登録日 2022-09-27 公開日 2023-03-29 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex. Nature, 615, 2023
8B6F	Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... 著者 Muhleip, A, Kock Flygaard, R, Amunts, A. 登録日 2022-09-27 公開日 2023-03-29 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex. Nature, 615, 2023
8B6E	crystal structure of the DNA-binding short chromatophore-targeted protein sCTP-23166 from Paulinella chromatophora 分子名称: 1,2-ETHANEDIOL, SODIUM ION, sCTP-23166 著者 Macorano, L, Applegate, V, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. 登録日 2022-09-27 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proc.Natl.Acad.Sci.USA, 120, 2023
8B6D	Crystal structure of UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 in complex with UDP 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SODIUM ION, ... 著者 Laustsen, J, Kumpf, A, Bento, I. 登録日 2022-09-27 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure determination of a highly active UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 To Be Published
8B6A	Crystal structure of BfrB protein from Bacteroides fragilis NCTC 9343 分子名称: Conserved hypothetical lipoprotein, GLYCEROL, SULFATE ION 著者 Antonyuk, S.V, Strange, R.W, Olczak, T. 登録日 2022-09-26 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Bacteroides fragilis expresses three proteins similar to Porphyromonas gingivalis HmuY: Hemophore-like proteins differentially evolved to participate in heme acquisition in oral and gut microbiomes. Faseb J., 37, 2023
8B68	Crystal structure of UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 in complex with UDP-glucose 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Laustsen, J.U, Bento, I. 登録日 2022-09-26 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure determination of a highly active UDP-glucose pyrophosphorylase from Thermocrispum agreste DSM 44070 To Be Published
8B65	Structure of rsCherry crystallized in anaerobic conditions 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Bui, T.Y.H, Van Meervelt, L. 登録日 2022-09-26 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Oxygen-induced chromophore degradation in the photoswitchable red fluorescent protein rsCherry. Int.J.Biol.Macromol., 239, 2023
8B62	Crystal Structure of P. aeruginosa WaaG in complex with UDP-galactose 分子名称: GALACTOSE-URIDINE-5'-DIPHOSPHATE, GLYCEROL, UDP-glucose:(Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG 著者 Scaletti, E, Gustafsson Westergren, R, Stenmark, P. 登録日 2022-09-25 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis. J.Biol.Chem., 299, 2023
8B61	Crystal structure of BfrC protein from Bacteroides fragilis NCTC 9343 分子名称: Conserved hypothetical lipoprotein, GLYCEROL, pentane-1,3,5-tricarboxylic acid 著者 Antonyuk, S.V, Barnett, K, Strange, R.W, Olczak, T. 登録日 2022-09-25 公開日 2023-05-31 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Bacteroides fragilis expresses three proteins similar to Porphyromonas gingivalis HmuY: Hemophore-like proteins differentially evolved to participate in heme acquisition in oral and gut microbiomes. Faseb J., 37, 2023
8B5V	Crystal Structure of Trypanosoma Cruzi phosphomannosemutase 分子名称: MAGNESIUM ION, PHOSPHATE ION, Phosphomannomutase 著者 Robinson, D.A, Ferguson, M.A.J. 登録日 2022-09-24 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Trypanosoma Cruzi phosphomannosemutase To Be Published
8B5O	Structure of haloalkane dehalogenase DmmarA from Mycobacterium marinum at pH 5.5 分子名称: ACETATE ION, FORMIC ACID, GLYCEROL, ... 著者 Snajdarova, K, Marek, M. 登録日 2022-09-23 公開日 2023-08-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.597 Å) 主引用文献 Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum. Acta Crystallogr D Struct Biol, 79, 2023
8B5K	Structure of haloalkane dehalogenase DmmarA from Mycobacterium marinum at pH 6.5 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, ... 著者 Snajdarova, K, Marek, M. 登録日 2022-09-23 公開日 2023-08-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum. Acta Crystallogr D Struct Biol, 79, 2023
8B5J	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 7,8-dimethoxy-1,3-dimethyl-1,3-dihydro-2H-benzo[d]azepin-2-one 分子名称: (5~{R})-7,8-dimethoxy-3,5-dimethyl-2,5-dihydro-1~{H}-3-benzazepin-4-one, 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Chung, C. 登録日 2022-09-22 公開日 2022-11-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432. J.Med.Chem., 65, 2022
8B5I	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 7,8-dimethoxy-1,3-dimethyl-1,3-dihydro-2H-benzo[d]azepin-2-one 分子名称: (1~{R})-7,8-dimethoxy-1,3-dimethyl-1~{H}-3-benzazepin-2-one, 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Chung, C. 登録日 2022-09-22 公開日 2022-11-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.604 Å) 主引用文献 Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432. J.Med.Chem., 65, 2022
8B5H	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH (R)-7-((R)-1,2-dihydroxyethyl)-1,3-dimethyl-5-(1-methyl-1H-pyrazol-4-yl)-1,3-dihydro-2H-benzo[d]azepin-2-one 分子名称: (1~{R})-7-[(1~{R})-1,2-bis(oxidanyl)ethyl]-1,3-dimethyl-5-(1-methylpyrazol-4-yl)-1~{H}-3-benzazepin-2-one, 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, ... 著者 Chung, C. 登録日 2022-09-22 公開日 2022-11-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432. J.Med.Chem., 65, 2022
8B5G	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 7,8-dimethoxy-3-methyl-1,3-dihydro-2H-benzo[d]azepin-2-one 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7,8-dimethoxy-3-methyl-1~{H}-3-benzazepin-2-one, ... 著者 Chung, C. 登録日 2022-09-22 公開日 2022-11-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.619 Å) 主引用文献 Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432. J.Med.Chem., 65, 2022
8B5F	Human cathepsin B in complex with the carbamate inhibitor 31 分子名称: (2S)-2-[[(2S)-2-[[3-chloranyl-4-[[3-phenyl-2-(phenylmethyl)propanoyl]amino]phenoxy]carbonylamino]-3-cyclohexyl-propanoyl]amino]-3-phenyl-propanoic acid, 1,2-ETHANEDIOL, Cathepsin B 著者 Rubesova, P, Guetschow, M, Mares, M. 登録日 2022-09-22 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Human cathepsin B in complex with the carbamate inhibitor 31 To Be Published
8B5E	Exploring the ligand binding and conformational dynamics of receptor domain 1 of the ABC transporter GlnPQ 分子名称: ABC transporter permease subunit, ARGININE, DI(HYDROXYETHYL)ETHER, ... 著者 Whittaker, J, Guskov, A. 登録日 2022-09-22 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Exploring the ligand binding and conformational dynamics of receptor domain 1 of the ABC transporter GlnPQ To Be Published
8B5D	Exploring the ligand binding and conformational dynamics of receptor domain 1 of the ABC transporter GlnPQ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ABC transporter permease subunit, DI(HYDROXYETHYL)ETHER, ... 著者 Whittaker, J, Guskov, A. 登録日 2022-09-22 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploring the ligand binding and conformational dynamics of receptor domain 1 of the ABC transporter GlnPQ To Be Published

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