PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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4P0V	Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione 分子名称: (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Liu, Y.L, Oldfield, E. 登録日 2014-02-23 公開日 2014-07-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. Proc.Natl.Acad.Sci.USA, 111, 2014
4P3H	Crystal structure of Kaposi's sarcoma-associated herpesvirus (KSHV) protease in complex with dimer disruptor 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, KSHV protease, ... 著者 Gable, J.E. 登録日 2014-03-07 公開日 2014-07-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry, 53, 2014
4L3E	The complex between high affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide 分子名称: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ... 著者 Hellman, L.M. 登録日 2013-06-05 公開日 2014-06-11 最終更新日 2014-08-27 実験手法 X-RAY DIFFRACTION (2.557 Å) 主引用文献 Computational design of the affinity and specificity of a therapeutic T cell receptor. PLOS COMPUT.BIOL., 10, 2014
4LBF	Crystal structure of HUMAN ALPHA-DEFENSIN 1 (HNP1) I20A/L25A mutant 分子名称: GLYCEROL, Neutrophil defensin 1 著者 Tolbert, W.D, Wu, X, Pazgier, M. 登録日 2013-06-20 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
4P0X	Human farnesyl diphosphate synthase in complex with Taxodione 分子名称: (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione, Farnesyl pyrophosphate synthase 著者 Liu, Y.L, Oldfield, E. 登録日 2014-02-23 公開日 2014-07-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. Proc.Natl.Acad.Sci.USA, 111, 2014
4L8M	Human p38 MAP kinase in complex with a Dibenzoxepinone 分子名称: Mitogen-activated protein kinase 14, N-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide, octyl beta-D-glucopyranoside 著者 Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D. 登録日 2013-06-17 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Metabolically Stable Dibenzo[b,e]oxepin-11(6H)-ones as Highly Selective p38 MAP Kinase Inhibitors: Optimizing Anti-Cytokine Activity in Human Whole Blood. J.Med.Chem., 56, 2013
4KVN	Crystal structure of Fab 39.29 in complex with Influenza Hemagglutinin A/Perth/16/2009 (H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Fong, R, Swem, L.R, Lupardus, P.J. 登録日 2013-05-22 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Novel In vivo Human Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Anti-Influenza A Antibodies Cell Host Microbe, 14, 2013
1WO3	Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain 分子名称: CREB Binding Protein, ZINC ION 著者 Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. 登録日 2004-08-12 公開日 2005-03-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
1WT8	Solution Structure of BmP08 from the Venom of Scorpion Buthus martensii Karsch, 20 structures 分子名称: Neurotoxin BmK X 著者 Wu, H, Chen, X, Tong, X, Li, Y, Zhang, N, Wu, G. 登録日 2004-11-17 公開日 2005-04-19 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of BmP08, a novel short-chain scorpion toxin from Buthus martensi Karsch. Biochem.Biophys.Res.Commun., 330, 2005
2M97	Optimized Ratiometric Calcium Sensors For Functional In Vivo Imaging of Neurons and T-Lymphocytes 分子名称: Optimized Ratiometric Calcium Sensor 著者 Russo, L, Becker, S, Griesinger, C. 登録日 2013-06-04 公開日 2014-01-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nat.Methods, 11, 2014
2LZO	Spatial structure of Pi-AnmTX Ugr 9a-1 分子名称: UGTX 著者 Mineev, K, Arseniev, A. 登録日 2012-10-08 公開日 2013-07-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Sea Anemone Peptide with Uncommon beta-Hairpin Structure Inhibits Acid-sensing Ion Channel 3 (ASIC3) and Reveals Analgesic Activity. J.Biol.Chem., 288, 2013
1X2U	NMR solution structures of a DNA dodecamer containing a tandem GT mismatches using NOE and residual dipolar couplings 分子名称: 5'-D(*GP*AP*CP*TP*GP*TP*AP*CP*AP*GP*TP*C)-3' 著者 Alvarez-Salgado, F, Desvaux, H, Boulard, Y. 登録日 2005-04-26 公開日 2006-08-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR assessment of the global shape of a non-labelled DNA dodecamer containing a tandem of G--T mismatches Magn.Reson.Chem., 44, 2006
1X2X	NMR solution structures of a DNA dodecamer containing a tandem GT mismatches using NOE and residual dipolar couplings 分子名称: 5'-D(*GP*AP*CP*TP*GP*TP*GP*CP*AP*GP*TP*C)-3' 著者 Alvarez-Salgado, F, Desvaux, H, Boulard, Y. 登録日 2005-04-26 公開日 2006-08-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR assessment of the global shape of a non-labelled DNA dodecamer containing a tandem of G--T mismatches Magn.Reson.Chem., 44, 2006
7EEB	Structure of the CatSpermasome 分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wu, J.P, Ke, M. 登録日 2021-03-18 公開日 2021-07-28 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of a mammalian sperm cation channel complex. Nature, 595, 2021
3MSN	Crystal structure of Thermolysin in complex with N-methylurea 分子名称: CALCIUM ION, GLYCEROL, N-METHYLUREA, ... 著者 Behnen, J, Heine, A, Klebe, G. 登録日 2010-04-29 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Experimental and computational active site mapping as a starting point to fragment-based lead discovery. Chemmedchem, 7, 2012
1WO6	Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain 分子名称: CREB Binding Protein, ZINC ION 著者 Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. 登録日 2004-08-12 公開日 2005-03-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
3NSQ	Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron 分子名称: 1,8-dihydroxyanthracene-9,10-dione, Retinoid X receptor, alpha 著者 Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. 登録日 2010-07-02 公開日 2010-11-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286, 2011
3O32	Crystal Structure of 4-Chlorocatechol Dioxygenase from Rhodococcus opacus 1CP in complex with 3,5-dichlorocatechol 分子名称: (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, 3,5-dichlorobenzene-1,2-diol, Chlorocatechol 1,2-dioxygenase, ... 著者 Ferraroni, M, Briganti, F, Kolomytseva, M, Golovleva, L. 登録日 2010-07-23 公開日 2011-08-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: new perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity. J. Struct. Biol., 181, 2013
3O5U	Crystal Structure of 4-Chlorocatechol Dioxygenase from Rhodococcus opacus 1CP in complex with protocatechuate 分子名称: (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, 3,4-DIHYDROXYBENZOIC ACID, CHLORIDE ION, ... 著者 Ferraroni, M, Briganti, F, Kolomitseva, M, Golovleva, L. 登録日 2010-07-28 公開日 2011-08-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: new perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity. J. Struct. Biol., 181, 2013
3NTG	Crystal structure of COX-2 with selective compound 23d-(R) 分子名称: (2R)-6,8-dichloro-7-(2-methylpropoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wang, J.L, Limburg, D, Graneto, M.J, Carter, J.C, Talley, J.J, Kiefer, J.R. 登録日 2010-07-04 公開日 2010-10-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life. Bioorg.Med.Chem.Lett., 20, 2010
1WO4	Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain 分子名称: CREB Binding Protein, ZINC ION 著者 Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. 登録日 2004-08-12 公開日 2005-03-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
1X2V	NMR solution structures of a DNA dodecamer containing a tandem GT mismatches using NOE and residual dipolar couplings 分子名称: 5'-D(*GP*AP*CP*TP*GP*TP*AP*CP*AP*GP*TP*C)-3' 著者 Alvarez-Salgado, F, Desvaux, H, Boulard, Y. 登録日 2005-04-26 公開日 2006-08-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR assessment of the global shape of a non-labelled DNA dodecamer containing a tandem of G--T mismatches Magn.Reson.Chem., 44, 2006
1X2Y	NMR Solution structures of a DNA dodecamer containing a tandem GT mismatches using NOE and residual dipolar couplings 分子名称: 5'-D(*GP*AP*CP*TP*GP*TP*GP*CP*AP*GP*TP*C)-3' 著者 Alvarez-Salgado, F, Desvaux, H, Boulard, Y. 登録日 2005-04-26 公開日 2006-08-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR assessment of the global shape of a non-labelled DNA dodecamer containing a tandem of G--T mismatches Magn.Reson.Chem., 44, 2006
3O8A	Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348 分子名称: Dihydroorotate dehydrogenase homolog, mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Deng, X, Booker, M.L, Phillips, M.A. 登録日 2010-08-02 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J.Biol.Chem., 285, 2010
2M4P	Solution structure of an intramolecular propeller-type G-quadruplex containing a single bulge 分子名称: DNA (5'-D(*TP*TP*GP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') 著者 Mukundan, V.T, Phan, A.T. 登録日 2013-02-08 公開日 2013-06-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences. J.Am.Chem.Soc., 135, 2013

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