6AO1
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6V4X
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![BU of 6v4x by Molmil](/molmil-images/mine/6v4x) | Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution | 分子名称: | Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ... | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | 登録日 | 2019-12-02 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of an active human histone pre-mRNA 3'-end processing machinery. Science, 367, 2020
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6K6W
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6K6S
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6M8Q
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![BU of 6m8q by Molmil](/molmil-images/mine/6m8q) | Cleavage and Polyadenylation Specificity Factor Subunit 3 (CPSF3) in complex with NVP-LTM531 | 分子名称: | Cleavage and polyadenylation specificity factor subunit 3, N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzene-1-carbonyl}-L-phenylalanine, PHOSPHATE ION, ... | 著者 | Weihofen, W.A, Salcius, M, Michaud, G. | 登録日 | 2018-08-22 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nat.Chem.Biol., 16, 2020
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7R3J
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![BU of 7r3j by Molmil](/molmil-images/mine/7r3j) | Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION, ... | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | 登録日 | 2022-02-07 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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7R3E
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![BU of 7r3e by Molmil](/molmil-images/mine/7r3e) | Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase,Regulatory protein RhlR, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | 登録日 | 2022-02-07 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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8DQ0
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![BU of 8dq0 by Molmil](/molmil-images/mine/8dq0) | Quorum-sensing receptor RhlR bound to PqsE | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, RhlR protein | 著者 | Paczkowski, J.E, Fromme, J.C, Feathers, J.R. | 登録日 | 2022-07-18 | 公開日 | 2022-12-07 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation. Structure, 30, 2022
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8DQ1
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![BU of 8dq1 by Molmil](/molmil-images/mine/8dq1) | Quorum-sensing receptor RhlR bound to PqsE | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, DNA (5'-D(*AP*CP*CP*TP*GP*CP*CP*AP*GP*AP*CP*TP*GP*CP*AP*CP*AP*G)-3'), ... | 著者 | Paczkowski, J.E, Fromme, J.C, Feathers, J.R. | 登録日 | 2022-07-18 | 公開日 | 2022-12-07 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation. Structure, 30, 2022
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3R2U
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![BU of 3r2u by Molmil](/molmil-images/mine/3r2u) | 2.1 Angstrom Resolution Crystal Structure of Metallo-beta-lactamase from Staphylococcus aureus subsp. aureus COL | 分子名称: | CHLORIDE ION, FE (III) ION, MAGNESIUM ION, ... | 著者 | Minasov, G, Wawrzak, Z, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Kiryukhina, O, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-03-14 | 公開日 | 2011-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 2.1 Angstrom Resolution Crystal Structure of Metallo-beta-lactamase Family Protein from Staphylococcus aureus subsp. aureus COL TO BE PUBLISHED
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5VE3
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![BU of 5ve3 by Molmil](/molmil-images/mine/5ve3) | Crystal structure of wild-type persulfide dioxygenase-rhodanese fusion protein from Burkholderia phytofirmans | 分子名称: | BpPRF, FE (III) ION | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | 登録日 | 2017-04-03 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.793 Å) | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J. Biol. Chem., 292, 2017
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5VE4
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![BU of 5ve4 by Molmil](/molmil-images/mine/5ve4) | Crystal structure of persulfide dioxygenase-rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans | 分子名称: | BpPRF, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | 登録日 | 2017-04-03 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J. Biol. Chem., 292, 2017
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5VE5
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![BU of 5ve5 by Molmil](/molmil-images/mine/5ve5) | Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans in complex with glutathione | 分子名称: | BpPRF, CHLORIDE ION, FE (III) ION, ... | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | 登録日 | 2017-04-03 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J. Biol. Chem., 292, 2017
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3TP9
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![BU of 3tp9 by Molmil](/molmil-images/mine/3tp9) | Crystal structure of Alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains | 分子名称: | BETA-LACTAMASE and RHODANESE DOMAIN PROTEIN, ZINC ION | 著者 | Michalska, K, Chhor, G, Mandel, M.E, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-09-07 | 公開日 | 2011-09-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of Alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains To be Published
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8B4A
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