4XO5
 
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2IVU
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4XQ6
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3W0U
 | | human Glyoxalase I with an N-hydroxypyridone inhibitor | | 分子名称: | Lactoylglutathione lyase, N-[3-(1-Hydroxy-6-oxo-4-phenyl-1,6-dihydro-pyridin-2-yl)-5-methanesulfonylamino-phenyl]-methanesulfonamide, ZINC ION | | 著者 | Fukami, T.A, Irie, M, Matsuura, T. | | 登録日 | 2012-11-02 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | N-Hydroxypyridone-based glyoxalase I inhibitors mimicking binding interactions of the substrate
to be published
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1JFF
 | | Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Lowe, J, Li, H, Downing, K.H, Nogales, E. | | 登録日 | 2001-06-20 | | 公開日 | 2001-09-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.5 Å) | | 主引用文献 | Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
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4Y2B
 | | Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one bound to PDE7A | | 分子名称: | 3-ethyl-2-(propan-2-ylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | | 著者 | Endo, Y, Kawai, K, Asano, T, Amano, S, Asanuma, Y, Sawada, K, Onodera, Y, Ueo, N, Takahashi, N, Sonoda, Y, Kamei, N, Irie, T. | | 登録日 | 2015-02-09 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy
Bioorg.Med.Chem.Lett., 25, 2015
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4XOM
 | | Coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain). | | 分子名称: | Coenzyme F420:L-glutamate ligase, SULFATE ION | | 著者 | Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. | | 登録日 | 2015-01-16 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
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2IUA
 | | C. trachomatis LpxD | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PALMITIC ACID, SULFATE ION, ... | | 著者 | Buetow, L, Smith, T.K, Dawson, A, Fyffe, S, Hunter, W.N. | | 登録日 | 2006-05-30 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and Reactivity of Lpxd, the N-Acyltransferase of Lipid a Biosynthesis
Proc.Natl.Acad.Sci.USA, 104, 2007
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4XYQ
 | | Structure of AgrA LytTR domain in complex with promoters | | 分子名称: | 1,2-ETHANEDIOL, Accessory gene regulator A, DNA (5'-D(*AP*AP*TP*AP*CP*TP*TP*AP*AP*CP*TP*GP*TP*TP*AP*A)-3'), ... | | 著者 | Gopal, B, Rajasree, K. | | 登録日 | 2015-02-03 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
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4XZJ
 | | Crystal structure of ADP-ribosyltransferase Vis in complex with NAD | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative NAD(+)--arginine ADP-ribosyltransferase Vis | | 著者 | Pfoh, R, Ravulapalli, R, Merrill, A.R, Pai, E.F. | | 登録日 | 2015-02-04 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus.
Biochemistry, 54, 2015
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2IYO
 | | Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition | | 分子名称: | 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, ... | | 著者 | Sundaramoorthy, R, Iulek, J, Hunter, W.N. | | 登録日 | 2006-07-21 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
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4XZK
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4YJF
 | | Crystal structure of DAAO(Y228L/R283G) variant (S-methylbenzylamine binding form) | | 分子名称: | (1S)-1-phenylethanamine, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Nakano, S, Yasukawa, K, Kawahara, N, Ishitsubo, E, Tokiwa, H, Asano, Y. | | 登録日 | 2015-03-03 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of DAAO variant
To Be Published
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4Y7P
 | | Structure of alkaline D-peptidase from Bacillus cereus | | 分子名称: | Alkaline D-peptidase, THIOCYANATE ION | | 著者 | Nakano, S, Okazaki, S, Ishitsubo, E, Kawahara, N, Komeda, H, Tokiwa, H, Asano, Y. | | 登録日 | 2015-02-15 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and computational analysis of peptide recognition mechanism of class-C type penicillin binding protein, alkaline D-peptidase from Bacillus cereus DF4-B
Sci Rep, 5, 2015
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2JKC
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4YW5
 | | Crystal Structure of Streptococcus pneumoniae NanC, complex with oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, GLYCEROL, ... | | 著者 | Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. | | 登録日 | 2015-03-20 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
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3UM9
 | | Crystal Structure of the Defluorinating L-2-Haloacid Dehalogenase Bpro0530 | | 分子名称: | Haloacid dehalogenase, type II, NICKEL (II) ION, ... | | 著者 | Chan, P.W.Y, Savchenko, A, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-11-12 | | 公開日 | 2012-11-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination
To be Published
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3V18
 | | Structure of the Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | | 分子名称: | 1-phosphatidylinositol phosphodiesterase, ISOPROPYL ALCOHOL, SULFATE ION | | 著者 | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | | 登録日 | 2011-12-09 | | 公開日 | 2012-04-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop
Biochemistry, 51, 2012
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2JKS
 | | Crystal structure of the the bradyzoite specific antigen BSR4 from toxoplasma gondii. | | 分子名称: | BRADYZOITE SURFACE ANTIGEN BSR4, ZINC ION | | 著者 | Boulanger, M.J, Grigg, M.E, Bruic, E, Grujic, O. | | 登録日 | 2008-08-29 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Characterization of the Bradyzoite Surface Antigen (Bsr4) from Toxoplasma Gondii, a Unique Addition to the Surface Antigen Glycoprotein 1-Related Superfamily.
J.Biol.Chem., 284, 2009
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5O8U
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4WXL
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6MLJ
 | | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S70A mutant from Salmonella typhimurium complexed with arginine | | 分子名称: | ACETATE ION, ARGININE, Lysine/arginine/ornithine transport protein | | 著者 | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | | 登録日 | 2018-09-27 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020
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6MLV
 | | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) Y14A mutant from Salmonella typhimurium | | 分子名称: | Lysine/arginine/ornithine-binding periplasmic protein | | 著者 | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | | 登録日 | 2018-09-28 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.082 Å) | | 主引用文献 | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020
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6ML0
 | | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S69A mutant from Salmonella typhimurium | | 分子名称: | ACETATE ION, GLYCEROL, Lysine/arginine/ornithine-binding periplasmic protein | | 著者 | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | | 登録日 | 2018-09-26 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020
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6MLI
 | | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) R77A mutant from Salmonella typhimurium complexed with histidine | | 分子名称: | ACETATE ION, GLYCEROL, HISTIDINE, ... | | 著者 | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | | 登録日 | 2018-09-27 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.883 Å) | | 主引用文献 | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
Febs J., 287, 2020
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