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9C3T
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Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTAAAC as recognition sequence
分子名称: DNA1, DNA2, Methyltransferase, ...
著者Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K.
登録日2024-06-02
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
9BOQ
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BU of 9boq by Molmil
Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)
分子名称: 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Nandi, P, DeVore, K, Chiu, P.-L.
登録日2024-05-05
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Commun Chem, 7, 2024
9B1G
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Human urate transporter 1 URAT1 in complex with dotinurad
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, dotinurad
著者Dai, Y, Lee, C.H.
登録日2024-03-13
公開日2024-09-18
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9EO5
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BU of 9eo5 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure C)
分子名称: AMMONIA, PLATINUM (II) ION, Ribonuclease pancreatic
著者Ferraro, G, Merlino, A.
登録日2024-03-14
公開日2024-05-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
9B1I
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Human urate transporter 1 URAT1 in complex with verinurad
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, verinurad
著者Dai, Y, Lee, C.H.
登録日2024-03-13
公開日2024-09-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9B8Y
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Cryo-EM structure of the human TRPM4 channel in complex with calcium and decavanadate at 37 degrees Celsius
分子名称: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B93
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Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius
分子名称: Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
8YL5
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The DSR2-DSAD1 complex with DSAD1 on the same sides
分子名称: DSAD1, SIR2-like domain-containing protein
著者Yang, X, Zheng, J.
登録日2024-03-05
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
9B1M
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Pyrazinoate bound human URAT1 in the inward-facing state (site1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12
著者Dai, Y, Lee, C.H.
登録日2024-03-13
公開日2024-09-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9B92
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Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
8ZTR
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The dimer complex of DSR2 and tube-forming domain of phage tail tube protein
分子名称: Bacillus phage SPR Tube protein, SIR2-like domain-containing protein
著者Zheng, J, Yang, X.
登録日2024-06-07
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
9BHT
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BU of 9bht by Molmil
Septin Hexameric Complex SEPT2/SEPT6/SEPT7 of Ciona intestinalis by Cryo-EM
分子名称: CiSeptin-2, CiSeptin-6, CiSeptin-7, ...
著者Mendonca, D.C, Pereira, H.M, Garratt, R.C.
登録日2024-04-22
公開日2024-07-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural Insights into Ciona intestinalis Septins: Complexes Suggest a Mechanism for Nucleotide-dependent Interfacial Cross-talk.
J.Mol.Biol., 436, 2024
9EMU
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BU of 9emu by Molmil
RosC-8-demethyl-8-amino-FMN - Phosphate complex
分子名称: 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, GLYCEROL, PHOSPHATE ION, ...
著者Ermler, U, Mack, M, Demmer, U.
登録日2024-03-11
公開日2024-09-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Phosphatase RosC from Streptomyces davaonensis is Used for Roseoflavin Biosynthesis and has Evolved to Largely Prevent Dephosphorylation of the Important Cofactor Riboflavin-5'-phosphate.
J.Mol.Biol., 436, 2024
9B94
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Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9GDM
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BU of 9gdm by Molmil
Solution structure of a silver ion mediated DNA duplex with universal 7-deazapurine substitutions
分子名称: ODNI-Ag, SILVER ION
著者Javornik, U, Plavec, J, Galindo, M.A.
登録日2024-08-06
公開日2024-09-18
実験手法SOLUTION NMR
主引用文献Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs.
Nat Commun, 15, 2024
8YLT
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BU of 8ylt by Molmil
The structure of DSR2 and NAD+ complex
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zheng, J, Yang, X.
登録日2024-03-06
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
9BHW
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BU of 9bhw by Molmil
Septin Tetrameric Complex SEPT7/SEPT9 of Ciona intestinalis by Cryo-EM
分子名称: CiSeptin-7, GUANOSINE-5'-DIPHOSPHATE, Neuronal-specific septin-3
著者Mendonca, D.C, Pereira, H.M, Garratt, R.C.
登録日2024-04-22
公開日2024-07-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural Insights into Ciona intestinalis Septins: Complexes Suggest a Mechanism for Nucleotide-dependent Interfacial Cross-talk.
J.Mol.Biol., 436, 2024
9BEW
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BU of 9bew by Molmil
Cryo-EM structure of the HIV-1 BG505 IDL Env trimer in complex with 3BNC117 and 10-1074 Fabs
分子名称: 10-1074 heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2024-04-16
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Cell Rep, 43, 2024
9B91
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BU of 9b91 by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8W
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BU of 9b8w by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9C3S
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BU of 9c3s by Molmil
Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTATAC as recognition sequence
分子名称: DNA1, DNA2, Methyltransferase, ...
著者Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K.
登録日2024-06-02
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
9EM8
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BU of 9em8 by Molmil
Oligomeric structure of SynDLP in presence of GDP
分子名称: Slr0869 protein
著者Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C.
登録日2024-03-07
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP.
Cell Rep, 43, 2024
9C49
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Cryo-EM structure of Danio rerio voltage-sensing phosphatase (VSP) phosphatase domain
分子名称: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2
著者Zhang, L, Brohawn, S.G.
登録日2024-06-03
公開日2024-07-10
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Coupling sensor to enzyme in the voltage sensing phosphatase.
Nat Commun, 15, 2024
9EOW
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BU of 9eow by Molmil
The 5-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH
分子名称: RNA (29-MER)
著者Wacker, A, Schwalbe, H.
登録日2024-03-15
公開日2024-06-19
最終更新日2024-07-31
実験手法SOLUTION NMR
主引用文献The 5'-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH.
Nucleic Acids Res., 52, 2024
6CHA
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STRUCTURE OF A TETRAHEDRAL TRANSITION STATE COMPLEX OF ALPHA-*CHYMOTRYPSIN AT 1.8-*ANGSTROMS RESOLUTION
分子名称: ALPHA-CHYMOTRYPSIN A, PHENYLETHANE BORONIC ACID
著者Tulinsky, A, Blevins, R.A.
登録日1987-02-06
公開日1987-04-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution.
J.Biol.Chem., 262, 1987

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件を2024-09-25に公開中

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