PDB: 1302 件ウェブページステータス検索Chemie searchBIRD

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6XA1	Structure of a drug-like compound stalled human translation termination complex 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J. 登録日 2020-06-03 公開日 2020-10-07 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Selective inhibition of human translation termination by a drug-like compound. Nat Commun, 11, 2020
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7OUG	STLV-1 intasome:B56 in complex with the strand-transfer inhibitor raltegravir 分子名称: DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), Integrase, ... 著者 Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N. 登録日 2021-06-11 公開日 2021-08-18 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures. Nat Commun, 12, 2021
7OUH	Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor bictegravir 分子名称: Bictegravir, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), ... 著者 Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N. 登録日 2021-06-11 公開日 2021-08-18 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures. Nat Commun, 12, 2021
5K52	Crystal structures of aldehyde deformylating oxygenase from Limnothrix sp. KNUA012 分子名称: Aldehyde decarbonylase, octadecanal 著者 Park, A.K, Kim, H-.W. 登録日 2016-05-23 公開日 2017-03-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of aldehyde deformylating oxygenase from Limnothrix sp. KNUA012 and Oscillatoria sp. KNUA011. Biochem. Biophys. Res. Commun., 477, 2016
4ETS	Crystal structure of Campylobacter jejuni ferric uptake regulator 分子名称: CHLORIDE ION, Ferric uptake regulation protein, ZINC ION 著者 Sarvan, S, Brunzelle, J.B, Couture, J.-F. 登録日 2012-04-24 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation. Proc.Natl.Acad.Sci.USA, 109, 2012
6Y0G	Structure of human ribosome in classical-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-07 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6NR6	Crystal Structure of Staphylococcus pseudintermedius SbnI in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Bifunctional transcriptional regulator/O-phospho-L-serine synthase SbnI, MAGNESIUM ION 著者 Verstraete, M.M, Morales, L.D, Kobylarz, M.J, Loutet, S.A, Laakso, H.A, Heinrichs, D.E, Murphy, M.E.P. 登録日 2019-01-22 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus . J.Biol.Chem., 294, 2019
8IFE	Arbekacin-added human 80S ribosome 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. 登録日 2023-02-17 公開日 2024-02-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.57 Å) 主引用文献 Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
8IFD	Dibekacin-added human 80S ribosome 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. 登録日 2023-02-17 公開日 2024-02-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.59 Å) 主引用文献 Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
8OTZ	48-nm repeat of the native axonemal doublet microtubule from bovine sperm 分子名称: ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ... 著者 Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T. 登録日 2023-04-21 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural specializations of the sperm tail. Cell, 186, 2023
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G51	Cryo-EM structure of a late human pre-40S ribosomal subunit - State D 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
8YOO	Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Denk, T, Cheng, J. 登録日 2024-03-13 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
6G53	Cryo-EM structure of a late human pre-40S ribosomal subunit - State E 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
8YOP	Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Denk, T, Cheng, J. 登録日 2024-03-13 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
3LL8	Crystal Structure of Calcineurin in Complex with AKAP79 Peptide 分子名称: AKAP79 peptide, CALCIUM ION, Calcineurin subunit B type 1, ... 著者 Li, H, Hogan, P.G. 登録日 2010-01-28 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat.Struct.Mol.Biol., 19, 2012
8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. 登録日 2023-03-22 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (1.67 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Z	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G6J	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) 分子名称: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-15 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Y	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G61	mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. 登録日 2022-02-09 公開日 2023-02-22 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
5SVA	Mediator-RNA Polymerase II Pre-Initiation Complex 分子名称: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... 著者 Robinson, P.J, Bushnell, D.A, Kornberg, R.D. 登録日 2016-08-05 公開日 2016-09-28 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (15.3 Å) 主引用文献 Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell, 166, 2016
7QVP	Human collided disome (di-ribosome) stalled on XBP1 mRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Denk, T.G, Tesina, P, Beckmann, R. 登録日 2022-01-22 公開日 2022-10-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nat Commun, 13, 2022

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