PDB: 11109 件ウェブページステータス検索Chemie searchBIRD

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7LXR	Kinesin-like protein at 61F (Klp61f) bound to AMPPNP 分子名称: 1,2-ETHANEDIOL, IODIDE ION, Kinesin-like protein Klp61F, ... 著者 Worthylake, D.K, Wojcik, E.J. 登録日 2021-03-04 公開日 2022-11-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.744 Å) 主引用文献 Crystal Structure of the Klp61f motor domain bound to AMPPNP To Be Published
1PX4	E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND 分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. 登録日 2003-07-02 公開日 2004-06-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase Biochemistry, 42, 2003
3ZKV	Importin13 cytosolic state 分子名称: CADMUS 著者 Gruenwald, M, Lazzaretti, D, Bono, F. 登録日 2013-01-24 公開日 2013-04-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis for the Nuclear Export Activity of Importin13. Embo J., 32, 2013
4BL6	Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein 分子名称: ARGININE, PROTEIN BICAUDAL D 著者 Liu, Y, Salter, H.K, Holding, A.N, Johnson, C.M, Stephens, E, Lukavsky, P.J, Walshaw, J, Bullock, S.L. 登録日 2013-05-02 公開日 2013-06-12 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Bicaudal-D Uses a Parallel, Homodimeric Coiled Coil with Heterotypic Registry to Coordinate Recruitment of Cargos to Dynein Genes Dev., 27, 2013
4AXG	Structure of eIF4E-Cup complex 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, PROTEIN CUP 著者 Kinkelin, K, Veith, K, Gruenwald, M, Bono, F. 登録日 2012-06-12 公開日 2012-08-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of a Minimal Eif4E-Cup Complex Revelas a General Mechanism of Eif4E Regulation in Translational Repression RNA, 18, 2012
8ZQF	Crystal structure of a novel alginate-binding carbohydrate binding module 分子名称: Alginate lyase 著者 Mei, X.W, Tao, W.W, Chang, Y.G. 登録日 2024-06-02 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a novel alginate-binding carbohydrate binding module To Be Published
9B1E	Cryo-EM structure of native SWR1 bound to nucleosome (composite structure) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... 著者 Louder, R.K, Park, G, Wu, C. 登録日 2024-03-13 公開日 2024-10-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler. Cell, 2024
8YE0	Crystal structure of KgpF prenyltransferase 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ... 著者 Hamada, K, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T. 登録日 2024-02-21 公開日 2024-06-19 最終更新日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands. Angew.Chem.Int.Ed.Engl., 63, 2024
6NYV	Structure of spastin AAA domain in complex with a quinazoline-based inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, N-(3-tert-butyl-1H-pyrazol-5-yl)-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, SULFATE ION, ... 著者 Pisa, R, Cupido, T, Kapoor, T.M. 登録日 2019-02-12 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.425 Å) 主引用文献 Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein. J. Am. Chem. Soc., 141, 2019
9C5E	Covalent Complex Between Parkin Catalytic (Rcat) Domain and Ubiquitin 分子名称: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION 著者 Connelly, E.M, Rintala-Dempsey, A.C, Gundogdu, M, Freeman, E.A, Koszela, J, Aguirre, J.D, Zhu, G, Kamarainen, O, Tadayon, R, Walden, H, Shaw, G.S. 登録日 2024-06-06 公開日 2024-08-14 最終更新日 2024-10-09 実験手法 SOLUTION NMR 主引用文献 Capturing the catalytic intermediates of parkin ubiquitination. Proc.Natl.Acad.Sci.USA, 121, 2024
9FTQ	Drosophila golgi alpha-mannosidase II (dGMII) in complex with swainsonine-configured alkyl indolizidine 分子名称: Alpha-mannosidase 2, DI(HYDROXYETHYL)ETHER, ZINC ION, ... 著者 Bennett, M, Koemans, T, Overkleeft, H.S, Davies, G.J. 登録日 2024-06-25 公開日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structure-guided design of C3-branched swainsonine as potent and selective human Golgi alpha-mannosidase (GMII) inhibitor. Chem.Commun.(Camb.), 2024
9AT8	Fab 77-stabilized MeV F ectodomain fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ... 著者 Zyla, D, Saphire, E.O. 登録日 2024-02-26 公開日 2024-07-03 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384, 2024
9FTR	Drosophila golgi alpha-mannosidase II (dGMII) in complex with amide modified swainsonine-configured alkyl indolizidine 分子名称: 1,2-ETHANEDIOL, Alpha-mannosidase 2, ZINC ION, ... 著者 Bennett, M, Koemans, T, Overkleeft, H.S, Davies, G.J. 登録日 2024-06-25 公開日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structure-guided design of C3-branched swainsonine as potent and selective human Golgi alpha-mannosidase (GMII) inhibitor. Chem.Commun.(Camb.), 2024
9C0O	Crystal structure of DmCfp1 PHD finger bound to H3K4me3 分子名称: CXXC-type zinc finger protein 1, DIMETHYL SULFOXIDE, Histone H3.3C, ... 著者 Gregoire, S, Couture, J.F. 登録日 2024-05-27 公開日 2024-07-03 最終更新日 2024-09-25 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural insights into an atypical histone binding mechanism by a PHD finger. Structure, 32, 2024
9C1U	Cryo-EM Structure of a Tm1C Fibril 分子名称: Tropomyosin 1 I/C 著者 Fonda, B.D, Kato, M, Li, Y, Murray, D.T. 登録日 2024-05-29 公開日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.31 Å) 主引用文献 Cryo-EM and solid state NMR together provide a more comprehensive structural investigation of protein fibrils. Protein Sci., 33, 2024
8HLS	Crystal structure of the sialidase Am1547 from A.muciniphila 分子名称: CHLORIDE ION, MAGNESIUM ION, Sialidase domain-containing protein 著者 Rui, B, Xinyue, T. 登録日 2022-11-30 公開日 2024-06-05 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural analysis of a novel sialidase from Akkermansia muciniphila reveals a distinct catalytic motif in GH33 family To Be Published
6NPW	SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide 分子名称: PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ... 著者 Irani, S, Zhang, Y. 登録日 2019-01-18 公開日 2019-04-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.486 Å) 主引用文献 Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription. J.Biol.Chem., 294, 2019
1JYX	E. COLI (lacZ) BETA-GALACTOSIDASE IN COMPLEX WITH IPTG 分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-Galactosidase, DIMETHYL SULFOXIDE, ... 著者 Juers, D.H, Matthews, B.W. 登録日 2001-09-13 公開日 2001-12-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
6NRX	Crystal structure of DIP-eta IG1 homodimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ... 著者 Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. 登録日 2019-01-24 公開日 2019-02-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
6NRQ	Crystal structure of Dpr10 IG1 bound to DIP-alpha IG1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Defective proboscis extension response 10, isoform A, ... 著者 Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. 登録日 2019-01-24 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
6NS1	Crystal structure of DIP-gamma IG1+IG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein gamma 著者 Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. 登録日 2019-01-24 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
6NYW	Structure of spastin AAA domain N527C mutant in complex with 8-fluoroquinazoline-based inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, N-(5-tert-butyl-1H-pyrazol-3-yl)-8-fluoro-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, ... 著者 Pisa, R, Cupido, T, Kapoor, T.M. 登録日 2019-02-12 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein. J. Am. Chem. Soc., 141, 2019
6NZV	Crystal structure of HCV NS3/4A protease in complex with compound 12 分子名称: (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, HCV NS3/4A protease, SULFATE ION, ... 著者 Appleby, T.C, Taylor, J.G. 登録日 2019-02-14 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®. Bioorg.Med.Chem.Lett., 29, 2019
6NWZ	Crystal structure of Agd3 a novel carbohydrate deacetylase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Bamford, N.C, Howell, P.L. 登録日 2019-02-07 公開日 2020-02-12 最終更新日 2020-08-26 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation. Nat Commun, 11, 2020
6WML	Human TLR8 bound to the potent agonist, GS-9688 (Selgantolimod) 分子名称: (2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino]-2-methylhexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... 著者 Appleby, T.C, Perry, J.K, Mish, M, Villasenor, A.G, Mackman, R.L. 登録日 2020-04-21 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B. J.Med.Chem., 63, 2020

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