PDB: 35439 件ウェブページステータス検索Chemie searchBIRD

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8DMD	Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound ZZ4461624291 分子名称: 1-[(3R)-4-[(3-chlorophenyl)methyl]-3-(2-methylpropyl)piperazin-1-yl]ethan-1-one, 3C-like proteinase 著者 Kovalevsky, A, Coates, L, Kneller, D.W. 登録日 2022-07-08 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
5XYW	Crystal structure of drosophila simulans Rhino chromoshadow domain in complex with N-terminal domain 分子名称: GD21652, Rhino 著者 Yu, B.W, Huang, Y. 登録日 2017-07-10 公開日 2018-06-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Structural insights into Rhino-Deadlock complex for germline piRNA cluster specification EMBO Rep., 19, 2018
8EUA	Structure of SARS-CoV2 PLpro bound to a covalent inhibitor 分子名称: Papain-like protease nsp3, SULFATE ION, ZINC ION, ... 著者 Mathews, I.I, Pokhrel, S, Wakatsuki, S. 登録日 2022-10-18 公開日 2023-04-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2. Nat Commun, 14, 2023
5XYV	Crystal structure of drosophila melanogaster Rhino chromoshadow domain in complex with Deadlock N-terminal domain 分子名称: Protein deadlock, RHINO 著者 Yu, B.W, Huang, Y. 登録日 2017-07-10 公開日 2018-06-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into Rhino-Deadlock complex for germline piRNA cluster specification EMBO Rep., 19, 2018
8DL9	Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z199538122 分子名称: 1-{4-[(naphthalen-1-yl)methyl]piperazin-1-yl}ethan-1-one, 3C-like proteinase 著者 Kovalevsky, A.Y, Coates, L, Kneller, D.W. 登録日 2022-07-07 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
8DLB	Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083 分子名称: 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase 著者 Kovalevsky, A.Y, Coates, L, Kneller, D.W. 登録日 2022-07-07 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
6E1C	Crystal structure of a MauG-like protein associated with microbial copper homeostasis 分子名称: CALCIUM ION, Di-heme enzyme, HEME C 著者 Dassama, L.M.K, Rosenzweig, A.C. 登録日 2018-07-09 公開日 2019-07-17 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (2.617 Å) 主引用文献 MbnH is a diheme MauG-like protein associated with microbial copper homeostasis. J.Biol.Chem., 294, 2019
4P1Z	Structure of the MID domain from MIWI 分子名称: Piwi-like protein 1 著者 Cora, E, McCarthy, A.A, Pillai, R.S. 登録日 2014-02-28 公開日 2014-05-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs. Rna, 20, 2014
7EXY	T-hairpin structure found in the RNA element involved in the piRNA biogenesis 分子名称: RNA (5'-R(*UP*UP*GP*GP*UP*UP*UP*GP*AP*UP*UP*CP*CP*AP*AP*G)-3') 著者 Takase, N, Kawai, G. 登録日 2021-05-29 公開日 2022-03-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 T-hairpin structure found in the RNA element involved in piRNA biogenesis. Rna, 28, 2022
4B9W	Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45. 分子名称: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1 著者 Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. 登録日 2012-09-08 公開日 2012-10-17 最終更新日 2019-04-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors. Rna, 18, 2012
4B9X	Structure of extended Tudor domain TD3 from mouse TDRD1 分子名称: TUDOR DOMAIN-CONTAINING PROTEIN 1 著者 Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. 登録日 2012-09-08 公開日 2012-10-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Multiple Tudor Domain-Containing Protein Tdrd1 is a Molecular Scaffold for Mouse Piwi Proteins and Pirna Biogenesis Factors. RNA, 18, 2012
7KY1	Molecular basis for control of antibiotic production by a bacterial hormones 分子名称: TetR family transcriptional regulator 著者 Bhukya, H, Fulop, V. 登録日 2020-12-06 公開日 2021-02-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5000335 Å) 主引用文献 Molecular basis for control of antibiotic production by a bacterial hormone. Nature, 590, 2021
6AKK	Crystal structure of the second Coiled-coil domain of SIKE1 分子名称: GLYCEROL, Suppressor of IKBKE 1 著者 Zhou, L, Chen, M, Zhou, Z.C. 登録日 2018-09-02 公開日 2019-01-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
6AKL	Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain 分子名称: Striatin-3, Suppressor of IKBKE 1 著者 Zhou, L, Chen, M, Zhou, Z.C. 登録日 2018-09-02 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
6AKM	Crystal structure of SLMAP-SIKE1 complex 分子名称: GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1 著者 Ma, J, Chen, M, Zhou, Z.C. 登録日 2018-09-02 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
4YBG	Crystal structure of the MAEL domain of Drosophila melanogaster Maelstrom 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Protein maelstrom, ... 著者 Matsumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. 登録日 2015-02-18 公開日 2015-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom Cell Rep, 11, 2015
4GEN	Crystal structure of Zucchini (monomer) 分子名称: CHLORIDE ION, Mitochondrial cardiolipin hydrolase 著者 Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. 登録日 2012-08-02 公開日 2012-10-17 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
4GEM	Crystal structure of Zucchini (K171A) 分子名称: 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, ZINC ION 著者 Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. 登録日 2012-08-02 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.206 Å) 主引用文献 Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
1ETT	REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS 分子名称: 4-[(2S)-2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-(piperidin-1-yl)propyl]benzene-1-carboximidamide, EPSILON-THROMBIN 著者 Bode, W, Brandstetter, H. 登録日 1992-07-06 公開日 1994-01-31 最終更新日 2018-09-12 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992
1ETR	REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS 分子名称: EPSILON-THROMBIN, amino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminium 著者 Bode, W, Brandstetter, H. 登録日 1992-07-06 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992
1ETS	REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS 分子名称: 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, EPSILON-THROMBIN 著者 Bode, W, Brandstetter, H. 登録日 1992-07-06 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992
4GEL	Crystal structure of Zucchini 分子名称: 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, PHOSPHATE ION, ... 著者 Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. 登録日 2012-08-02 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.756 Å) 主引用文献 Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
6SRN	Structural basis for control of antibiotic production by bacterial hormones 分子名称: 4-(Hydroxymethyl)-2-propylfuran-3-carboxylic acid, GLYCEROL, TetR family transcriptional regulator 著者 Fulop, V. 登録日 2019-09-05 公開日 2020-09-30 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular basis for control of antibiotic production by a bacterial hormone. Nature, 590, 2021
5CEG	X-ray structure of toxin/anti-toxin complex from Mesorhizobium opportunistum 分子名称: Addiction module antidote protein, CopG/Arc/MetJ family, GLYCEROL, ... 著者 Aakre, C.D, Herrou, J, Crosson, S, Laub, M.T. 登録日 2015-07-06 公開日 2015-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates. Cell, 163, 2015
3TH5	Crystal structure of wild-type RAC1 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 著者 Ha, B.H, Boggon, T.J. 登録日 2011-08-18 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012

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