PDB: 615 件ウェブページステータス検索Chemie searchBIRD

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8XXN	Cryo-EM structure of the human 43S ribosome with PDCD4 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. 登録日 2024-01-18 公開日 2024-05-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
8Y6O	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. 登録日 2024-02-02 公開日 2024-03-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
8YLE	Crystal structure of Werner syndrome helicase complexed with AMP-PCP 分子名称: 1,2-ETHANEDIOL, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Yang, Y, Fu, L, Sun, X, Cheng, H, Chen, R. 登録日 2024-03-06 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure of werner syndrome helicase complexed with AMP-PCP at 1.86 Angstroms resolution. To Be Published
9ASJ	Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form 分子名称: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-02-26 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9ASK	Human DNA polymerase theta helicase domain dimer, apo-form 分子名称: DNA polymerase theta 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-02-26 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9ASL	Human DNA polymerase theta helicase domain tetramer, apo-form 分子名称: DNA polymerase theta 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-02-26 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9BH6	Human DNA polymerase theta helicase domain tetramer in the apo form 分子名称: DNA polymerase theta 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH7	Human DNA polymerase theta helicase domain dimer in the apo form 分子名称: DNA polymerase theta 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH8	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH9	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BHA	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BP9	Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form 分子名称: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-05-07 公開日 2024-08-28 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
9BPA	Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form 分子名称: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-05-07 公開日 2024-08-28 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
9C5Q	Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form 分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta 著者 Ito, F, Li, Z, Chen, X.S. 登録日 2024-06-06 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9FMD	Integrative model of the human post-catalytic spliceosome (P-complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Rothe, P, Plaschka, C, Vorlaender, M.K. 登録日 2024-06-05 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism for the initiation of spliceosome disassembly. Nature, 2024

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