6IH7
 
 | | Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - 3',3'-cGAMP bound form | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, cyclic di nucleotide phoshodiesterase | | 著者 | Yadav, M, Pal, K, Sen, U. | | 登録日 | 2018-09-28 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
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7CR7
 | | human KCNQ2-CaM in complex with retigabine | | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | | 登録日 | 2020-08-12 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
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7CUY
 | | Crystal structure of Primo-1 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase 1 | | 著者 | Lee, H.S, Kim, S.J, Ku, B. | | 登録日 | 2020-08-25 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1.
Mol.Cells, 43, 2020
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4G7N
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6IH1
 | | Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - c-di-GMP bound form | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, cyclic di nucleotide phoshodiesterase | | 著者 | Yadav, M, Pal, K, Sen, U. | | 登録日 | 2018-09-28 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
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4PXT
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6IFQ
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6IJ2
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4UT6
 | | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, ... | | 著者 | Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. | | 登録日 | 2014-07-18 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
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4PXU
 | | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Bipolar kinesin KRP-130 | | 著者 | Scholey, J.E, Nithianantham, S, Scholey, J.M, Al-Bassam, J. | | 登録日 | 2014-03-25 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers.
Elife, 3, 2014
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4W9Y
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2NQN
 | | MoeA T100W | | 分子名称: | GLYCEROL, Molybdopterin biosynthesis protein moeA | | 著者 | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | | 登録日 | 2006-10-31 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
Biochemistry, 46, 2007
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2NMB
 | | DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES. | | 分子名称: | PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN) | | 著者 | Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D. | | 登録日 | 1998-10-29 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
Nat.Struct.Biol., 5, 1998
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4HP4
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2NQR
 | | MoeA D142N | | 分子名称: | GLYCEROL, Molybdopterin biosynthesis protein moeA | | 著者 | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | | 登録日 | 2006-10-31 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
Biochemistry, 46, 2007
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2ND8
 | | Structures of DK17 in TBLE LUVS | | 分子名称: | Cell penetrating peptide | | 著者 | Bera, S, Bhunia, A. | | 登録日 | 2016-05-11 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier
Biochemistry, 55, 2016
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4UT9
 | | Crystal structure of dengue 2 virus envelope glycoprotein dimer in complex with the ScFv fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10, ENVELOPE GLYCOPROTEIN E | | 著者 | Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. | | 登録日 | 2014-07-18 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
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4UZJ
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4V4L
 | | Structure of the Drosophila apoptosome | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apaf-1 related killer DARK, MAGNESIUM ION | | 著者 | Yuan, S, Topf, M, Akey, C.W, Ludtke, S.J. | | 登録日 | 2010-10-04 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Structure of the Drosophila apoptosome at 6.9 angstrom resolution
Structure, 19, 2011
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7CQH
 | | Complex of TRP_CBS2 and Calmodulin_Clobe | | 分子名称: | AT15141p, CALCIUM ION, Transient receptor potential protein | | 著者 | Shen, Z.S. | | 登録日 | 2020-08-10 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
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7CRF
 | | Crystal structure of human TLR8 in complex with CU-CPD107 | | 分子名称: | 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-yl]-2-methyl-propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | | 著者 | Sakaniwa, K, Tanji, H, Ohto, U, Shimizu, T. | | 登録日 | 2020-08-13 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists.
Nat Commun, 12, 2021
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2NQV
 | | MoeA D228A | | 分子名称: | GLYCEROL, Molybdopterin biosynthesis protein moeA | | 著者 | Nciolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | | 登録日 | 2006-10-31 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
Biochemistry, 46, 2007
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7CQV
 | | Complex of TRP_CBS1 and Calmodulin_Nlobe | | 分子名称: | AT15141p, CALCIUM ION, Transient receptor potential protein | | 著者 | Shen, Z.S. | | 登録日 | 2020-08-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
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2NQK
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2NQB
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