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3CQD
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Structure of the tetrameric inhibited form of phosphofructokinase-2 from Escherichia coli
分子名称: 6-phosphofructokinase isozyme 2, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Ambrosio, A.L, Cabrera, R, Caniuguir, A, Garratt, R.C, Babul, J.
登録日2008-04-02
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystallographic structure of phosphofructokinase-2 from Escherichia coli in complex with two ATP molecules. Implications for substrate inhibition.
J.Mol.Biol., 383, 2008
3AWK
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Crystal structure of the polyketide synthase 1 from huperzia serrata
分子名称: Chalcone synthase-like polyketide synthase, GLYCEROL, SULFATE ION
著者Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I.
登録日2011-03-23
公開日2011-08-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
1NL7
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Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5
分子名称: Acetyl-CoA acetyltransferase, COENZYME A, SULFATE ION
著者Kursula, P, Wierenga, R.K.
登録日2003-01-06
公開日2004-04-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structures of Z. ramigera biosynthetic thiolase
To be Published
3AWJ
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Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH
分子名称: COENZYME A, Chalcone synthase-like polyketide synthase, SULFATE ION
著者Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I.
登録日2011-03-23
公開日2011-08-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
1RQE
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Propionibacterium shermanii transcarboxylase 5S subunit bound to oxaloacetate
分子名称: COBALT (II) ION, OXALOACETATE ION, transcarboxylase 5S subunit
著者Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C.
登録日2003-12-05
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit.
Embo J., 23, 2004
1YVK
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Crystal Structure of the Bacillis subtilis Acetyltransferase in complex with CoA, Northeast Structural Genomics Target SR237.
分子名称: COENZYME A, hypothetical protein BSU33890
著者Forouhar, F, Yong, W, Xiao, R, Ciano, M, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-02-15
公開日2005-02-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal Structure of the Bacillis subtilis Acetyltransferase in complex with CoA, Northeast Structural Genomics Target SR237.
To be Published
1X09
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Crystal structure of the D26A mutant UPPs in complex with magnesium and isopentenyl pyrophosphate
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, Undecaprenyl pyrophosphate synthetase
著者Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H.
登録日2005-03-15
公開日2005-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.
J.Biol.Chem., 280, 2005
3B1R
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Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with AMP-Mg-AMP
分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Ribokinase, ...
著者Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T.
登録日2011-07-05
公開日2011-11-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
2D09
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A Role for Active Site Water Molecules and Hydroxyl Groups of Substrate for Oxygen Activation in Cytochrome P450 158A2
分子名称: FLAVIOLIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhao, B, Waterman, M.R.
登録日2005-07-30
公開日2005-10-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer
J.Biol.Chem., 280, 2005
1F0N
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MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTIGEN 85B
著者Anderson, D.H, Harth, G, Horwitz, M.A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2000-05-16
公開日2001-01-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase.
J.Mol.Biol., 307, 2001
1F0P
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MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B WITH TREHALOSE
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTIGEN 85-B, ...
著者Anderson, D.H, Harth, G, Horwitz, M.A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2000-05-16
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase.
J.Mol.Biol., 307, 2001
1EZF
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CRYSTAL STRUCTURE OF HUMAN SQUALENE SYNTHASE
分子名称: FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE, N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1,4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID
著者Pandit, J, Danley, D.E, Schulte, G.K, Mazzalupo, S.M, Pauly, T.A, Hayward, C.M, Hamanaka, E.S, Thompson, J.F, Harwood, H.J.
登録日2000-05-10
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.
J.Biol.Chem., 275, 2000
1WK4
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Crystal structure of ttk003001606
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ttk003001606
著者Kaminishi, T, Sakai, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-30
公開日2004-11-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ttk003001606
To be Published
2CNM
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RimI - Ribosomal S18 N-alpha-protein acetyltransferase in complex with a bisubstrate inhibitor (Cterm-Arg-Arg-Phe-Tyr-Arg-Ala-N-alpha- acetyl-S-CoA).
分子名称: 30S RIBOSOMAL PROTEIN S18, COENZYME A, MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18
著者Vetting, M.W, Yu, M, Bareich, D.C, Blanchard, J.S.
登録日2006-05-22
公開日2007-05-22
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Rimi from Salmonella Typhimurium Lt2, the Gnat Responsible for N{Alpha}- Acetylation of Ribosomal Protein S18.
Protein Sci., 17, 2008
1RF5
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Structural Studies of Streptococcus pneumoniae EPSP Synthase in Unliganded State
分子名称: 5-enolpyruvylshikimate-3-phosphate synthase
著者Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C.
登録日2003-11-07
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
3B8G
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Crysta structure of N-acetylglutamate synthase from Neisseria gonorrhoeae complexed with coenzyme A and N-acetyl-glutamate
分子名称: COENZYME A, N-ACETYL-L-GLUTAMATE, Putative acetylglutamate synthase
著者Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
登録日2007-11-01
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
4AVC
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Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2012-08-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AXX
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The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP 3-phosphoglycerate and beryllium trifluoride
分子名称: 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Bowler, M.W.
登録日2012-06-15
公開日2013-06-26
最終更新日2024-08-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes, a practical guide.
Structure, 2024
1NAW
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ENOLPYRUVYL TRANSFERASE
分子名称: CYCLOHEXYLAMMONIUM ION, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYL-TRANSFERASE
著者Schoenbrunn, E, Sack, S, Eschenburg, S, Perrakis, A, Krekel, F, Amrhein, N, Mandelkow, E.
登録日1996-07-23
公開日1997-07-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin.
Structure, 4, 1996
4JJX
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Dodecameric structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae O1 biovar eltor
分子名称: Spermidine n1-acetyltransferase
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-03-08
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure.
J.Mol.Biol., 427, 2015
3VJB
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Crystal structure of the human squalene synthase
分子名称: Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
4JRH
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Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P43) at 2.2 Angstrom
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION
著者Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-03-21
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献

3VKB
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Crystal structure of MoeO5 soaked with FsPP overnight
分子名称: CHLORIDE ION, MAGNESIUM ION, MoeO5, ...
著者Ren, F, Ko, T.-P, Huang, C.-H, Guo, R.-T.
登録日2011-11-11
公開日2012-05-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes
Angew.Chem.Int.Ed.Engl., 51, 2012
3B7X
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Crystal structure of human FK506-Binding Protein 6
分子名称: FK506-binding protein 6
著者Walker, J.R, Davis, T, Butler-Cole, C, Paramanathan, R, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-10-31
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human FK506-Binding Protein 6.
To be Published
1QH4
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CRYSTAL STRUCTURE OF CHICKEN BRAIN-TYPE CREATINE KINASE AT 1.41 ANGSTROM RESOLUTION
分子名称: ACETATE ION, CALCIUM ION, CREATINE KINASE
著者Eder, M, Schlattner, U, Becker, A, Wallimann, T, Kabsch, W, Fritz-Wolf, K.
登録日1999-05-11
公開日1999-11-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Crystal structure of brain-type creatine kinase at 1.41 A resolution.
Protein Sci., 8, 1999

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