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2KN9
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Solution structure of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Seattle Structural Genomics Center for Infectious Disease target MytuD.01635.a
分子名称: Rubredoxin, ZINC ION
著者Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-08-20
公開日2009-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 67, 2011
1ESB
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DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE
分子名称: CALCIUM ION, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, PORCINE PANCREATIC ELASTASE, ...
著者Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D.
登録日1994-02-04
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Biochemistry, 33, 1994
3TT6
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Structure of ClpP from Bacillus subtilis in compressed state
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Lee, B.-G, Kim, M.K, Song, H.K.
登録日2011-09-14
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.592 Å)
主引用文献Structural insights into the conformational diversity of ClpP from Bacillus subtilis
Mol.Cells, 32, 2011
1ELC
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BU of 1elc by Molmil
Analogous inhibitors of elastase do not always bind analogously
分子名称: 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE
著者Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D.
登録日1993-12-07
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
2R5G
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BU of 2r5g by Molmil
Structure of human CLIC2, crystal form B
分子名称: Chloride intracellular channel protein 2
著者Gorman, M.A, Hansen, G, Cromer, B.A, Parker, M.W.
登録日2007-09-03
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure of the Janus Protein Human CLIC2
J.Mol.Biol., 374, 2007
1EQR
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BU of 1eqr by Molmil
CRYSTAL STRUCTURE OF FREE ASPARTYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI
分子名称: ASPARTYL-TRNA SYNTHETASE, MAGNESIUM ION
著者Rees, B, Webster, G, Delarue, M, Boeglin, M, Moras, D.
登録日2000-04-06
公開日2000-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates.
J.Mol.Biol., 299, 2000
2LEG
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BU of 2leg by Molmil
Membrane protein complex DsbB-DsbA structure by joint calculations with solid-state NMR and X-ray experimental data
分子名称: Disulfide bond formation protein B, Thiol:disulfide interchange protein DsbA, UBIQUINONE-1, ...
著者Tang, M, Sperling, L.J, Berthold, D.A, Schwieters, C.D, Nesbitt, A.E, Nieuwkoop, A.J, Gennis, R.B, Rienstra, C.M.
登録日2011-06-15
公開日2011-10-26
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献High-resolution membrane protein structure by joint calculations with solid-state NMR and X-ray experimental data.
J.Biomol.Nmr, 51, 2011
2L1Z
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BU of 2l1z by Molmil
NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures
分子名称: Insulin A chain, Insulin B chain
著者Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A.
登録日2010-08-09
公開日2011-08-31
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Chiral Protein Engineering and its Application in G Health
To be Published
2L4V
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Three Dimensional Structure of Pineapple Cystatin
分子名称: Cystatin
著者Chyan, C.C.L, Deli, I.I, Chen, B.B.J.
登録日2010-10-15
公開日2011-10-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Resonance assignments and secondary structure of a phytocystatin from Ananas comosus
Biomol.Nmr Assign., 6, 2012
2LF1
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BU of 2lf1 by Molmil
Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures
分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Polshakov, V, Feeney, J, Birdsall, B, Kovalevskaya, N.
登録日2011-06-28
公開日2011-12-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions
Biochemistry, 50, 2011
2LTQ
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BU of 2ltq by Molmil
High resolution structure of DsbB C41S by joint calculation with solid-state NMR and X-ray data
分子名称: Disulfide bond formation protein B, Fab fragment heavy chain, Fab fragment light chain, ...
著者Tang, M, Sperling, L.J, Schwieters, C.D, Nesbitt, A.E, Gennis, R.B, Rienstra, C.M.
登録日2012-05-30
公開日2013-02-27
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer.
J.Mol.Biol., 425, 2013
4FRV
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Crystal structure of mutated cyclophilin B that causes hyperelastosis cutis in the American Quarter Horse
分子名称: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, Peptidyl-prolyl cis-trans isomerase, ...
著者Boudko, S.P, Ishikawa, Y, Bachinger, H.P.
登録日2012-06-26
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse.
BMC Res Notes, 5, 2012
1X4U
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BU of 1x4u by Molmil
Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein
分子名称: ZINC ION, Zinc finger, FYVE domain containing 27 isoform b
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein
To be Published
3D84
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BU of 3d84 by Molmil
Structural Analysis of a Holo Enzyme Complex of Mouse Dihydrofolate Reductase with NADPH and a Ternary Complex with the Potent and Selective Inhibitor 2.4-Diamino-6-(-2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine
分子名称: Dihydrofolate reductase, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V.
登録日2008-05-22
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine.
Acta Crystallogr.,Sect.D, 64, 2008
3QRJ
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The crystal structure of human abl1 kinase domain T315I mutant in complex with DCC-2036
分子名称: 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, Tyrosine-protein kinase ABL1
著者Chan, W.W, Wise, S.C, Kaufman, M.D, Ahn, Y.M, Ensinger, C.L, Haack, T, Hood, M.M, Jones, J, Lord, J.W, Lu, W.P, Miller, D, Patt, W.C, Smith, B.D, Petillo, P.A, Rutkoski, T.J, Telikepalli, H, Vogeti, L, Yao, T, Chun, L, Clark, R, Evangelista, P, Gavrilescu, L.C, Lazarides, K, Zaleskas, V.M, Stewart, L.J, Van Etten, R.A, Flynn, D.L.
登録日2011-02-18
公開日2011-06-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036.
Cancer Cell, 19, 2011
3UN3
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phosphopentomutase T85Q variant soaked with glucose 1,6-bisphosphate
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, GLYCEROL, MANGANESE (II) ION, ...
著者Iverson, T.M, Birmingham, W.R, Panosian, T.D, Nannemann, D.P, Bachmann, B.O.
登録日2011-11-15
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Differences between a Mutase and a Phosphatase: Investigations of the Activation Step in Bacillus cereus Phosphopentomutase.
Biochemistry, 51, 2012
2ZFH
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BU of 2zfh by Molmil
Crystal structure of putative CutA1 from Homo sapiens at 2.05A resolution
分子名称: CutA
著者Bagautdinov, B, Yutani, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-01-07
公開日2008-01-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of putative CutA1 from Homo sapiens determined at 2.05 A resolution.
Acta Crystallogr.,Sect.F, 64, 2008
2D8L
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Crystal Structure of Unsaturated Rhamnogalacturonyl Hydrolase in complex with dGlcA-GalNAc
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, Putative glycosyl hydrolase yteR
著者Itoh, T, Ochiai, A, Mikami, B, Hashimoto, W, Murata, K.
登録日2005-12-06
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide
J.Mol.Biol., 360, 2006
3R35
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BU of 3r35 by Molmil
Crystal structure of Arthrobacter sp. strain SU 4-hydroxybenzoyl CoA thioesterase mutant E73D complexed with 4-hydroxyphenacyl CoA
分子名称: 4-HYDROXYPHENACYL COENZYME A, 4-hydroxybenzoyl-CoA thioesterase
著者Holden, H.M, Thoden, J.B, Song, F, Zhuang, Z, Trujillo, M, Dunaway-Mariano, D.
登録日2011-03-15
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU.
Biochemistry, 51, 2012
2LZX
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Solution NMR structure of Asteropsin B from a marine sponge Asteropus sp.
分子名称: Asteropsin B
著者Li, H, Bowling, J.J, Hamann, M.T, Jung, J.H.
登録日2012-10-11
公開日2013-10-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Sponge Derived Linear Knottins as a Novel Scaffold for Oral Peptide Drug Administration
To be Published
1N7W
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Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J.
登録日2002-11-18
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study
J.Biol.Chem., 278, 2003
2DC6
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BU of 2dc6 by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA073 complex
分子名称: BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, GLYCEROL, PHOSPHATE ION, ...
著者Watanabe, D.
登録日2005-12-28
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
1NGJ
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BU of 1ngj by Molmil
STRUCTURAL BASIS OF THE 70-KILODALTON HEAT SHOCK COGNATE PROTEIN ATP HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT
分子名称: HEAT-SHOCK COGNATE 70 kD PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Flaherty, K.M, Wilbanks, S.M, Deluca-Flaherty, C, Mckay, D.B.
登録日1994-05-17
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment.
J.Biol.Chem., 269, 1994
2DC7
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X-ray crystal structure analysis of bovine spleen cathepsin B-CA042 complex
分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-THREONYL-L-ISOLEUCINE, ...
著者Watanabe, D.
登録日2005-12-31
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
1N84
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HUMAN SERUM TRANSFERRIN, N-LOBE
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J.
登録日2002-11-19
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003

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