1VIU
 
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8PND
 | | The ES3 intermediate of hydroxymethylbilane synthase R167Q variant | | 分子名称: | 1,2-ETHANEDIOL, 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, GLYCEROL, ... | | 著者 | Saeter, M.C, Bustad, H.J, Laitaoja, M, Janis, J, Martinez, A, Aarsand, A.K, Kallio, J.P. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | One ring closer to a closure: the crystal structure of the ES 3 hydroxymethylbilane synthase intermediate.
Febs J., 291, 2024
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7VUM
 | | Crystal structure of SSB complexed with que | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Single-stranded DNA-binding protein | | 著者 | Lin, E.S, Huang, Y.H, Huang, C.Y. | | 登録日 | 2021-11-03 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.319 Å) | | 主引用文献 | A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity.
Int J Mol Sci, 23, 2022
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1PN0
 | | Phenol hydroxylase from Trichosporon cutaneum | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHENOL, ... | | 著者 | Enroth, C. | | 登録日 | 2003-06-12 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | High-resolution structure of phenol hydroxylase and correction of sequence errors.
Acta Crystallogr.,Sect.D, 59, 2003
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5KK3
 | | Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils | | 分子名称: | Beta-amyloid protein 42 | | 著者 | Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G. | | 登録日 | 2016-06-20 | | 公開日 | 2016-07-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils.
J.Am.Chem.Soc., 138, 2016
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5YEV
 | | Murine DR3 death domain | | 分子名称: | SULFATE ION, TNFRSF25 death domain | | 著者 | Yin, X, Jin, T. | | 登録日 | 2017-09-19 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
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8RD6
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1LKA
 | | Porcine Pancreatic Elastase/Ca-Complex | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Weiss, M.S, Panjikar, S, Nowak, E, Tucker, P.A. | | 登録日 | 2002-04-24 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Metal binding to porcine pancreatic elastase: calcium or not calcium.
Acta Crystallogr.,Sect.D, 58, 2002
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5Z09
 | | ST0452(Y97N)-UTP binding form | | 分子名称: | Dual sugar-1-phosphate nucleotidylyltransferase, URIDINE 5'-TRIPHOSPHATE | | 著者 | Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y. | | 登録日 | 2017-12-19 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering
Appl. Environ. Microbiol., 84, 2018
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5LUD
 | | Structure of Cyclophilin A in complex with 2,3-Diaminopyridine | | 分子名称: | Peptidyl-prolyl cis-trans isomerase, pyridine-2,3-diamine | | 著者 | McNae, I.W, Nowicki, M.W, Blackburn, E.A, Wear, M.A, Walkinshaw, M.D. | | 登録日 | 2016-09-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Thermo-kinetic analysis space expansion for cyclophilin-ligand interactions - identification of a new nonpeptide inhibitor using BiacoreTM T200.
FEBS Open Bio, 7, 2017
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8BWU
 | | Crystal structure of SARS-CoV-2 nsp14 methyltransferase domain in complex with the SS148 inhibitor | | 分子名称: | (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-azanyl-5-cyano-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, Transcription factor ETV6,Proofreading exoribonuclease nsp14, ZINC ION | | 著者 | Konkolova, E, Klima, M, Boura, E, Jin, J, Kaniskan, H.U, Han, Y, Vedadi, M. | | 登録日 | 2022-12-07 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.
Biorxiv, 2024
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1LKB
 | | Porcine Pancreatic Elastase/Na-Complex | | 分子名称: | CHLORIDE ION, Elastase 1, SODIUM ION, ... | | 著者 | Weiss, M.S, Panjikar, S, Nowak, E, Tucker, P.A. | | 登録日 | 2002-04-24 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Metal binding to porcine pancreatic elastase: calcium or not calcium.
Acta Crystallogr.,Sect.D, 58, 2002
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5Z3J
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5ZE8
 | | Crystal structure of a penta-heme cytochrome c552 from Thermochromatium tepidum | | 分子名称: | GLYCEROL, HEME C, SULFATE ION, ... | | 著者 | Yu, L.-J, Chen, J.-H, Shen, J.-R. | | 登録日 | 2018-02-27 | | 公開日 | 2018-04-25 | | 最終更新日 | 2019-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Properties and structure of a low-potential, penta-heme cytochrome c552from a thermophilic purple sulfur photosynthetic bacterium Thermochromatium tepidum.
Photosyn. Res., 139, 2019
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5LRQ
 | | BRD4 in complex with ERK5 inhibitor XMD8-92 | | 分子名称: | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain-containing protein 4 | | 著者 | Martin, M.P, Noble, M.E.M. | | 登録日 | 2016-08-19 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38 alpha and BRD4.
Eur.J.Med.Chem., 178, 2019
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5Z3I
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6MXR
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5Z37
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5Z7B
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6MY4
 | | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR] | | 分子名称: | 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain | | 著者 | Shi, R, Picard, M.-E, Manenda, M. | | 登録日 | 2018-11-01 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
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5ZST
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4KN8
 | | Crystal structure of Bs-TpNPPase | | 分子名称: | Thermostable NPPase | | 著者 | Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C. | | 登録日 | 2013-05-09 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
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6MXS
 | | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M] | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | | 著者 | Shi, R, Picard, M.-E, Manenda, M.S. | | 登録日 | 2018-10-31 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
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5ZUH
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6MY5
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