9G8K

Structure of K+-dependent Na+-PPase from Thermotoga maritima in complex with Ca2+ and Etidronate

Summary for 9G8K

• Entry DOI: 10.2210/pdb9g8k/pdb
• Descriptor: K(+)-stimulated pyrophosphate-energized sodium pump, (1-hydroxyethane-1,1-diyl)bis(phosphonic acid), MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: complex, inhibitor, enzyme, transport, membrane protein
• Biological source: Thermotoga maritima
• Total number of polymer chains: 2
• Total formula weight: 158166.47

Authors

Vidilaseris, K.,Liu, J.,Goldman, A. (deposition date: 2024-07-23, release date: 2025-06-04)

• Primary citation: Liu, J.,Shah, A.,Ma, Y.,Hardman, K.,Johansson, N.G.,Ribeiro, O.,Brookfield, A.,Bowen, A.,Yli-Kauhaluoma, J.,Xhaard, H.,Jeuken, L.J.,Goldman, A.,Pliotas, C.,Vidilaseris, K.; Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases; Elife, 2024; DOI: 10.7554/elife.102288.1

Experimental method

X-RAY DIFFRACTION (3.15 Å)