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4IZ6
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BU of 4iz6 by Molmil
Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry
分子名称: 4'-PHOSPHOPANTETHEINE, 5'-deoxy-5'-({[2-(2,3-dihydroxyphenyl)ethyl]sulfonyl}amino)adenosine, Enterobactin synthase component E, ...
著者Gulick, A.M, Sundlov, J.A.
登録日2013-01-29
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry.
Acta Crystallogr.,Sect.D, 69, 2013
3JAI
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BU of 3jai by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
登録日2015-06-10
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
6VAJ
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BU of 6vaj by Molmil
Crystal Structure Analysis of human PIN1
分子名称: 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ...
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-12-17
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat.Chem.Biol., 17, 2021
6WCW
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BU of 6wcw by Molmil
Structure of human Rubicon RH domain in complex with GTP-bound Rab7
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7a, ...
著者Bhargava, H.K, Byck, J.M, Farrell, D.P, Anishchenko, I, DiMaio, F, Im, Y.J, Hurley, J.H.
登録日2020-03-31
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NS1
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BU of 6ns1 by Molmil
Crystal structure of DIP-gamma IG1+IG2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein gamma
著者Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
登録日2019-01-24
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
8B9D
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BU of 8b9d by Molmil
Human replisome bound by Pol Alpha
分子名称: Cell division control protein 45 homolog, Claspin, DNA Molecule, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
7MU9
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BU of 7mu9 by Molmil
Solution NMR structure of the XVIPCD region from the T4SS effector X-Tfe(XAC2609) from Xanthomonas citri
分子名称: VirD4 interacting protein conserved domain
著者Oka, G.U, Salinas, R.K, Farah, C.S.
登録日2021-05-14
公開日2021-12-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for effector recognition by an antibacterial type IV secretion system.
Proc.Natl.Acad.Sci.USA, 119, 2022
8C3C
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BU of 8c3c by Molmil
14-3-3 sigma with Pin1 binding site pS72 and bound Fusicoccin A
分子名称: 14-3-3 protein sigma, FUSICOCCIN, MAGNESIUM ION, ...
著者Verhoef, C.J, Cossar, P.
登録日2022-12-23
公開日2023-06-14
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.
Chem Sci, 14, 2023
3HFM
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BU of 3hfm by Molmil
STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX
分子名称: HEN EGG WHITE LYSOZYME, HYHEL-10 IGG1 FAB (HEAVY CHAIN), HYHEL-10 IGG1 FAB (LIGHT CHAIN)
著者Padlan, E.A, Davies, D.R.
登録日1988-08-11
公開日1989-07-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.
Proc.Natl.Acad.Sci.USA, 86, 1989
8CDD
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BU of 8cdd by Molmil
PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003
分子名称: Cy.003 heavy chain, Cy.003 light chain, Cysteine-rich protective antigen, ...
著者Farrell, B, Higgins, M.K.
登録日2023-01-30
公開日2023-10-25
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The PfRCR complex bridges malaria parasite and erythrocyte during invasion.
Nature, 625, 2024
3CF5
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BU of 3cf5 by Molmil
Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans
分子名称: 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, 50S RIBOSOMAL PROTEIN L14, ...
著者Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P.
登録日2008-03-02
公開日2008-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3O3J
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BU of 3o3j by Molmil
Crystal structure of Arabidopsis thaliana peptide deformylase 1B (AtPDF1B) in complex with inhibitor 6b
分子名称: 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, Peptide deformylase 1B, ZINC ION
著者Fieulaine, S, Meinnel, T, Giglione, C.
登録日2010-07-24
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis
Plos Biol., 9, 2011
6SAM
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BU of 6sam by Molmil
Structure of human butyrylcholinesterase in complex with 1-(2,3-dihydro-1H-inden2-yl)piperidin-3-yl N-phenyl carbamate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ...
著者Brazzolotto, X, Kosak, U, Strasek, N, Knez, D, Gobec, S, Nachon, F.
登録日2019-07-17
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.
Eur.J.Med.Chem., 197, 2020
3M6O
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BU of 3m6o by Molmil
Crystal structure of Arabidopsis thaliana peptide deformylase 1B (AtPDF1B)
分子名称: Peptide deformylase 1B, ZINC ION
著者Fieulaine, S, Meinnel, T, Giglione, C.
登録日2010-03-16
公開日2011-03-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis
Plos Biol., 9, 2011
7NSJ
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BU of 7nsj by Molmil
55S mammalian mitochondrial ribosome with tRNA(P/P) and tRNA(E*)
分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
著者Kummer, E, Schubert, K, Ban, N.
登録日2021-03-07
公開日2021-06-02
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7B7A
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BU of 7b7a by Molmil
ENDO-POLYGALACTURONASE FROM ARABIDOPSIS THALIANA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pectin lyase-like superfamily protein, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Safran, J, Tabi, W, Habrylo, O, Bouckaert, J, Lefebvre, V, Senechal, F, Pelloux, J.
登録日2020-12-10
公開日2022-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins.
Plant Cell, 2023
7B8B
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BU of 7b8b by Molmil
ADPG2 - ENDOPOLYGALACTURONASE FROM ARABIDOPSIS THALIANA
分子名称: PHOSPHATE ION, Polygalacturonase ADPG2
著者Safran, J, Tabi, W, Habrylo, O, Bouckaert, J, Lefebvre, V, Senechal, F, Pelloux, J.
登録日2020-12-12
公開日2022-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins.
Plant Cell, 2023
8CDE
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BU of 8cde by Molmil
PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003
分子名称: Cy.003, Cy.003 light chain, Cysteine-rich protective antigen, ...
著者Farrell, B, Higgins, M.K.
登録日2023-01-30
公開日2023-10-25
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The PfRCR complex bridges malaria parasite and erythrocyte during invasion.
Nature, 625, 2024
8CYF
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BU of 8cyf by Molmil
WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA
分子名称: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), ...
著者Wan, T, Zhang, L.M.
登録日2022-05-23
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis.
J.Biol.Chem., 299, 2023
6TLG
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BU of 6tlg by Molmil
Ligand-free state of human 14-3-3 sigma isoform
分子名称: 14-3-3 protein sigma, DI(HYDROXYETHYL)ETHER, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-02
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
7NQL
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BU of 7nql by Molmil
55S mammalian mitochondrial ribosome with ICT1 and P site tRNAMet
分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
著者Kummer, E, Schubert, K, Ban, N.
登録日2021-03-01
公開日2021-05-05
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NQH
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BU of 7nqh by Molmil
55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet
分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
著者Kummer, E, Schubert, K, Ban, N.
登録日2021-03-01
公開日2021-05-05
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
5JA2
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BU of 5ja2 by Molmil
EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the non-Native MbtH-Like Protein PA2412
分子名称: 5'-({[(2R,3S)-3-amino-4-hydroxy-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}butyl]sulfonyl}amino)-5'-deoxyadenosine, Enterobactin synthase component F, MbtH-Like Protein PA2412, ...
著者Miller, B.R, Gulick, A.M.
登録日2016-04-11
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture.
J.Biol.Chem., 291, 2016
8C2G
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BU of 8c2g by Molmil
14-3-3 sigma with Pin1 binding site pS72 and covalently bound CV1040
分子名称: 14-3-3 protein sigma, 2-iodanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ...
著者Verhoef, C.J, Cossar, P.
登録日2022-12-22
公開日2023-06-14
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.
Chem Sci, 14, 2023
7OBX
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BU of 7obx by Molmil
Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide
分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
著者Centorrino, F, Andlovic, B, Ottmann, C.
登録日2021-04-23
公開日2022-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Cell Chem Biol, 2023

222415

件を2024-07-10に公開中

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