1E7W
 
 | | One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes | | 分子名称: | 1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Gourley, D.G, Hunter, W.N. | | 登録日 | 2000-09-11 | | 公開日 | 2001-09-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites.
Nat.Struct.Biol., 8, 2001
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1EAG
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5LP6
 | | Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | | 登録日 | 2016-08-11 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Tools for the rational design of bivalent microtubule-targeting drugs.
Biochem. Biophys. Res. Commun., 479, 2016
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1EB4
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7RW3
 | | E. coli cysteine desulfurase SufS N99D | | 分子名称: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Dunkle, J.A, Gogar, R, Frantom, P.A. | | 登録日 | 2021-08-19 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
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5LX7
 | | Cys-Gly dipeptidase GliJ mutant D38N | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dipeptidase, FE (III) ION, ... | | 著者 | Huber, E.M, Groll, M. | | 登録日 | 2016-09-20 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.
ACS Chem. Biol., 12, 2017
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9G7A
 | | CryoEM structure of human rho1 GABAA receptor in complex with loreclezole | | 分子名称: | 1-[(~{Z})-2-chloranyl-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Fan, C, Howard, R.J, Lindahl, E. | | 登録日 | 2024-07-20 | | 公開日 | 2025-07-30 | | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | | 主引用文献 | CryoEM structure of human rho1 GABAA receptor in complex with neurosteroid
To be published
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1EBO
 | | CRYSTAL STRUCTURE OF THE EBOLA VIRUS MEMBRANE-FUSION SUBUNIT, GP2, FROM THE ENVELOPE GLYCOPROTEIN ECTODOMAIN | | 分子名称: | CHLORIDE ION, EBOLA VIRUS ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO A FRAGMENT OF GP2, ZINC ION | | 著者 | Weissenhorn, W, Carfi, A, Lee, K.H, Skehel, J.J, Wiley, D.C. | | 登録日 | 1998-11-03 | | 公開日 | 1999-07-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.
Mol.Cell, 2, 1998
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5LY7
 | | Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin | | 分子名称: | 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, Beta-hexosaminidase, DI(HYDROXYETHYL)ETHER | | 著者 | Acebron, I, Artola-Recolons, C, Mahasenan, K, Mobashery, S, Hermoso, J.A. | | 登録日 | 2016-09-25 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.
J. Am. Chem. Soc., 139, 2017
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1EC4
 | | SOLUTION STRUCTURE OF A HEXITOL NUCLEIC ACID DUPLEX WITH FOUR CONSECUTIVE T:T BASE PAIRS | | 分子名称: | HEXITOL DODECANUCLEOTIDE | | 著者 | Lescrinier, E, Esnouf, R.M, Schraml, J, Busson, R, Herdewijn, P. | | 登録日 | 2000-01-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a HNA-RNA hybrid
Chem.Biol., 7, 2000
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5LPN
 | | Structure of human Rab10 in complex with the bMERB domain of Mical-1 | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein-methionine sulfoxide oxidase MICAL1, ... | | 著者 | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. | | 登録日 | 2016-08-14 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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1ECW
 | | CRYSTAL STRUCTURE OF SIMIAN IMMUNODEFICIENCY VIRUS MATRIX ANTIGEN (SIV MA) AT 293K. | | 分子名称: | GAG POLYPROTEIN, ISOPROPYL ALCOHOL | | 著者 | Rao, Z, Belyaev, A, Fry, E, Roy, P, Jones, I.M, Stuart, D.I. | | 登録日 | 2000-01-26 | | 公開日 | 2000-02-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of SIV matrix antigen and implications for virus assembly.
Nature, 378, 1995
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1ED1
 | | CRYSTAL STRUCTURE OF SIMIAN IMMUNODEFICIENCY VIRUS MATRIX ANTIGEN (SIV MA) AT 100K. | | 分子名称: | GAG POLYPROTEIN, ISOPROPYL ALCOHOL | | 著者 | Rao, Z, Belyaev, A, Fry, E, Roy, P, Jones, I.M, Stuart, D.I. | | 登録日 | 2000-01-26 | | 公開日 | 2000-02-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of SIV matrix antigen and implications for virus assembly.
Nature, 378, 1995
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1ED8
 | | STRUCTURE OF E. COLI ALKALINE PHOSPHATASE INHIBITED BY THE INORGANIC PHOSPHATE AT 1.75A RESOLUTION | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stec, B, Holtz, K.M, Kantrowitz, E.R. | | 登録日 | 2000-01-27 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A revised mechanism for the alkaline phosphatase reaction involving three metal ions.
J.Mol.Biol., 299, 2000
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5LZ9
 | | Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 | | 分子名称: | 2-fluoranyl-5-[2-[(4~{S})-4-[4-methyl-1,1-bis(oxidanylidene)thian-4-yl]-2-oxidanylidene-pyrrolidin-1-yl]ethoxy]benzenecarbonitrile, CHLORIDE ION, Platelet-activating factor acetylhydrolase, ... | | 著者 | Woolford, A, Day, P. | | 登録日 | 2016-09-29 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).
J. Med. Chem., 59, 2016
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5LZN
 | | -TIP microtubule-binding domain | | 分子名称: | Calmodulin-regulated spectrin-associated protein 3 | | 著者 | Stangier, M.M, Steinmetz, M.O. | | 登録日 | 2016-09-30 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nat. Struct. Mol. Biol., 24, 2017
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1EE4
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5LRN
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1EEY
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7RRN
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5LS0
 | | Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Soluble inorganic pyrophosphatase 1 | | 著者 | Grzechowiak, M, Sikorski, M, Jaskolski, M. | | 登録日 | 2016-08-22 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structures of plant inorganic pyrophosphatase, an enzyme with a moonlighting autoproteolytic activity.
Biochem.J., 476, 2019
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5LZP
 | | Binding of the C-terminal GQYL motif of the bacterial proteasome activator Bpa to the 20S proteasome | | 分子名称: | Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta | | 著者 | Bolten, M, Delley, C.L, Leibundgut, M, Boehringer, D, Ban, N, Weber-Ban, E. | | 登録日 | 2016-09-30 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural Analysis of the Bacterial Proteasome Activator Bpa in Complex with the 20S Proteasome.
Structure, 24, 2016
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1EGH
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5M00
 | | Crystal structure of murine P14 TCR complex with H-2Db and Y4A, modified gp33 peptide from LCMV | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Achour, A, Sandalova, T, Sun, R, Han, X. | | 登録日 | 2016-10-03 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant
To Be Published
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1EGW
 | | CRYSTAL STRUCTURE OF MEF2A CORE BOUND TO DNA | | 分子名称: | DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, ... | | 著者 | Santelli, E, Richmond, T.J. | | 登録日 | 2000-02-17 | | 公開日 | 2000-03-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of MEF2A core bound to DNA at 1.5 A resolution.
J.Mol.Biol., 297, 2000
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