PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

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1K4H	CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one 分子名称: 2,6-DIAMINO-8-PROPYLSULFANYLMETHYL-3H-QUINAZOLINE-4-ONE, TRNA-GUANINE-TRANSGLYCOSYLASE, ZINC ION 著者 Brenk, R, Meyer, E.A, Castellano, R.K, Furler, M, Stubbs, M.T, Klebe, G, Diederich, F. 登録日 2001-10-08 公開日 2002-04-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity. Chembiochem, 3, 2002
1FSV	FULL SEQUENCE DESIGN 1 (FSD-1) OF BETA BETA ALPHA MOTIF, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: FULL SEQUENCE DESIGN 1 OF BETA BETA ALPHA MOTIF 著者 Dahiyat, B.I, Mayo, S.L. 登録日 1997-10-26 公開日 1998-01-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 De novo protein design: fully automated sequence selection. Science, 278, 1997
1FSD	FULL SEQUENCE DESIGN 1 (FSD-1) OF BETA BETA ALPHA MOTIF, NMR, 41 STRUCTURES 分子名称: FULL SEQUENCE DESIGN 1 OF BETA BETA ALPHA MOTIF 著者 Dahiyat, B.I, Mayo, S.L. 登録日 1997-06-09 公開日 1997-11-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 De novo protein design: fully automated sequence selection. Science, 278, 1997
1FFQ	CRYSTAL STRUCTURE OF CHITINASE A COMPLEXED WITH ALLOSAMIDIN 分子名称: 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, CHITINASE A 著者 Papanikolau, Y, Tavlas, G, Vorgias, C.E, Petratos, K. 登録日 2000-07-26 公開日 2003-02-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 De novo purification scheme and crystallization conditions yield high-resolution structures of chitinase A and its complex with the inhibitor allosamidin. Acta Crystallogr.,Sect.D, 59, 2003
1K4G	CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-DIAMINO-8-(1H-IMIDAZOL-2-YLSULFANYLMETHYL)-3H-QUINAZOLINE-4-ONE 分子名称: 2,6-DIAMINO-8-(1H-IMIDAZOL-2-YLSULFANYLMETHYL)-3H-QUINAZOLINE-4-ONE, TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION 著者 Brenk, R, Meyer, E.A, Castellano, R.K, Furler, M, Stubbs, M.T, Klebe, G, Diederich, F. 登録日 2001-10-08 公開日 2002-04-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity. ChemBioChem, 3, 2002
6L0L	Hydra-1ubq de nova designed by Hydra based on ubiquitin 分子名称: Hydra-1ubq 著者 Ouyang, B. 登録日 2019-09-26 公開日 2020-09-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Multiobjective heuristic algorithm for de novo protein design in a quantified continuous sequence space. Comput Struct Biotechnol J, 19, 2021
2BE9	Crystal structure of the CTP-liganded (T-State) aspartate transcarbamoylase from the extremely thermophilic archaeon Sulfolobus acidocaldarius 分子名称: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 De Vos, D, Savvides, S.N, Van Beeumen, J.J. 登録日 2005-10-23 公開日 2006-10-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of Sulfolobus acidocaldarius aspartate carbamoyltransferase in complex with its allosteric activator CTP. Biochem.Biophys.Res.Commun., 372, 2008
2BE7	Crystal structure of the unliganded (T-state) aspartate transcarbamoylase of the psychrophilic bacterium Moritella profunda 分子名称: Aspartate Carbamoyltransferase Catalytic Chain, Aspartate Carbamoyltransferase Regulatory Chain, SULFATE ION, ... 著者 De Vos, D, Savvides, S.N, Van Beeumen, J. 登録日 2005-10-23 公開日 2006-10-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural investigation of cold activity and regulation of aspartate carbamoyltransferase from the extreme psychrophilic bacterium Moritella profunda. J.Mol.Biol., 365, 2007
3FBX	Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Lakomek, K, Dickmanns, A, Mueller, U, Ficner, R. 登録日 2008-11-20 公開日 2009-03-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse Acta Crystallogr.,Sect.D, 65, 2009
5L31	Crystal structure of an engineered metal-free RIDC1 variant containing five disulfide bonds. 分子名称: HEME C, SODIUM ION, Soluble cytochrome b562 著者 Tezcan, F.A, Churchfield, L.A. 登録日 2016-08-02 公開日 2016-11-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds. J.Am.Chem.Soc., 138, 2016
5L32	Crystal structure of the Zn-RIDC1 complex bearing six interfacial disulfide bonds 分子名称: HEME C, HEXAETHYLENE GLYCOL, Soluble cytochrome b562, ... 著者 Churchfield, L.A, Tezcan, F.A. 登録日 2016-08-02 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds. J.Am.Chem.Soc., 138, 2016
3B5L	Crystal Structure of a Novel Engineered Retroaldolase: RA-61 分子名称: AMMONIUM ION, Endoxylanase, SULFATE ION 著者 Stoddard, B.L, Doyle, L.A. 登録日 2007-10-26 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 De novo computational design of retro-aldol enzymes. Science, 319, 2008
1EDQ	CRYSTAL STRUCTURE OF CHITINASE A FROM S. MARCESCENS AT 1.55 ANGSTROMS 分子名称: CHITINASE A 著者 Papanikolau, Y, Petratos, K. 登録日 2000-01-28 公開日 2000-02-18 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 De novo purification scheme and crystallization conditions yield high-resolution structures of chitinase A and its complex with the inhibitor allosamidin. Acta Crystallogr.,Sect.D, 59, 2003
1EKY	MODEL STRUCTURE FROM NON-NOE BASED NMR STRUCTURE CALCULATION 分子名称: CYTOCHROME C', PROTOPORPHYRIN IX CONTAINING FE 著者 Hus, J.C, Marion, D, Blackledge, M. 登録日 2000-03-10 公開日 2000-03-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 De novo determination of protein structure by NMR using orientational and long-range order restraints. J.Mol.Biol., 298, 2000
7RKC	Computationally designed tunable C2 symmetric tandem repeat homodimer, D_3_633 分子名称: ACETATE ION, D_3_633 著者 Kennedy, M.A, Stoddard, B.L, Hicks, D.R, Bera, A.K. 登録日 2021-07-22 公開日 2022-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 De novo design of protein homodimers containing tunable symmetric protein pockets. Proc.Natl.Acad.Sci.USA, 119, 2022
3HOJ	Crystal Structure of a Novel Engineered Retroaldolase: RA-22 分子名称: RETROALDOLASE-22 著者 Stoddard, B.L, Doyle, L.A. 登録日 2009-06-02 公開日 2009-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 De Novo Computational Design of Retro-Aldol Enzymes Science, 319, 2008
1Q7O	Determination of f-MLF-OH Peptide Structure with solid-state magic-angle spinning NMR Spectroscopy 分子名称: chemotactic peptide 著者 Rienstra, C.M, Tucker-Kellogg, L, Jaroniec, C.P, Hohwy, M, Reif, B, McMahon, M.T, Tidor, B, Lozano-Perez, T, Griffin, R.G. 登録日 2003-08-19 公開日 2003-09-09 最終更新日 2022-03-02 実験手法 SOLID-STATE NMR 主引用文献 De novo determination of peptide structure with solid-state magic-angle spinning NMR Spectroscopy Proc.Natl.Acad.Sci.USA, 99, 2002
1PSV	COMPUTATIONALLY DESIGNED PEPTIDE WITH A BETA-BETA-ALPHA FOLD SELECTION, NMR, 32 STRUCTURES 分子名称: PDA8D 著者 Dahiyat, B.I, Sarisky, C.A, Mayo, S.L. 登録日 1997-10-29 公開日 1998-01-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 De novo protein design: towards fully automated sequence selection. J.Mol.Biol., 273, 1997
2MUZ	ssNMR structure of a designed rocker protein 分子名称: designed rocker protein 著者 Wang, T, Joh, N, Wu, Y, DeGrado, W.F, Hong, M. 登録日 2014-09-18 公開日 2014-12-24 最終更新日 2015-01-14 実験手法 SOLUTION NMR 主引用文献 De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
7QDI	Structure of octameric left-handed 310-helix bundle: D-310HD 分子名称: 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(2-METHOXYETHOXY)ETHANOL, ... 著者 Kumar, P, Paterson, N.G, Woolfson, D.N. 登録日 2021-11-27 公開日 2022-04-27 最終更新日 2022-07-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 De novo design of discrete, stable 3 10 -helix peptide assemblies. Nature, 607, 2022
7QDJ	Racemic structure of PK-10 and PK-11 分子名称: GLYCEROL, MALONATE ION, PK-10+PK-11, ... 著者 Kumar, P, Paterson, N.G, Woolfson, D.N. 登録日 2021-11-27 公開日 2022-04-27 最終更新日 2022-07-27 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 De novo design of discrete, stable 3 10 -helix peptide assemblies. Nature, 607, 2022
7UDK	Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide 分子名称: 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4 著者 Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. 登録日 2022-03-20 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
7UDL	Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide 分子名称: 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6 著者 Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. 登録日 2022-03-20 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
7UDN	Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 2 分子名称: Designed helical repeat protein (DHR) RPB_PLP1_R6 著者 Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. 登録日 2022-03-20 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
7VU4	de novo design based on 1r26 分子名称: de novo design protein 著者 Zhang, L. 登録日 2021-11-01 公開日 2022-06-08 最終更新日 2023-06-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rotamer-free protein sequence design based on deep learning and self-consistency. Nat Comput Sci, 2023

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