PDB: 896 件ウェブページステータス検索Chemie searchBIRD

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6CUN	Engineered Cytochrome c from Rhodothermus marinus (Rma TDE) bound to carbene intermediate (1-ethoxy-1-oxopropan-2-ylidene) 分子名称: Cytochrome c, ETHYL PROPIONATE, HEME C 著者 Lewis, R.D, Buller, A.R, Arnold, F.H. 登録日 2018-03-26 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Catalytic iron-carbene intermediate revealed in a cytochromeccarbene transferase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CXK	G9 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa 分子名称: ARYLSULFATASE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. 登録日 2014-04-07 公開日 2015-04-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5HHT	Crystal structure of E. coli transketolase triple variant Ser385Tyr/Asp469Thr/Arg520Gln 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, THIAMINE DIPHOSPHATE, ... 著者 Dai, S, Tittmann, K. 登録日 2016-01-11 公開日 2016-11-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes. Sci Rep, 6, 2016
2ZNI	Crystal structure of Pyrrolysyl-tRNA synthetase-tRNA(Pyl) complex from Desulfitobacterium hafniense 分子名称: CALCIUM ION, Pyrrolysyl-tRNA synthetase, bacterial tRNA 著者 Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O. 登録日 2008-04-25 公開日 2008-12-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality Nature, 457, 2009
6AH7	D45W/H226G mutant of marine bacterial prolidase 分子名称: MANGANESE (II) ION, SODIUM ION, SULFATE ION, ... 著者 Jian, Y, Yunzhu, X, Lijuan, L. 登録日 2018-08-17 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity. Biotechnol.Bioeng., 117, 2020
6AH8	Marine bacterial prolidase with promiscuous organophosphorus hydrolase activity 分子名称: MANGANESE (II) ION, SULFATE ION, Xaa-Pro dipeptidase 著者 Jian, Y. 登録日 2018-08-17 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity. Biotechnol.Bioeng., 117, 2020
2ZNJ	Crystal structure of Pyrrolysyl-tRNA synthetase from Desulfitobacterium hafniense 分子名称: Putative uncharacterized protein 著者 Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O. 登録日 2008-04-25 公開日 2008-12-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality Nature, 457, 2009
5OOY	Designed Ankyrin Repeat Protein (DARPin) VHAH-1 in complex with Lysozyme 分子名称: DARPin VHAH-1, Lysozyme C 著者 Hogan, B.J, Fischer, G, Houlihan, G, Edmond, S, Huovinen, T.T.K, Hollfelder, F, Hyvonen, M. 登録日 2017-08-09 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Designed Ankyrin Repeat Protein (DARPin) VHAH-1 in complex with Lysozyme To be published
4V1D	Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius. 分子名称: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ... 著者 Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B. 登録日 2014-09-25 公開日 2015-10-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin. J.Biol.Chem., 291, 2016
5OP1	Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme 分子名称: CHLORIDE ION, DARPin A4, Lysozyme C 著者 Fischer, G, Hogan, B.J, Houlihan, G, Edmond, S, Huovinen, T.T.K, Hollfelder, F, Hyvonen, M. 登録日 2017-08-09 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.284 Å) 主引用文献 Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme To be published
5OOV	Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme 分子名称: DARPin ETVD-1, Lysozyme C 著者 Houlihan, G, Fischer, G, Hogan, B.J, Edmond, S, Huovinen, T.T.K, Hollfelder, F, Hyvonen, M. 登録日 2017-08-08 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.365 Å) 主引用文献 Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme To be published
4UUI	A case study for twinned data analysis: multiple crystal forms of the enzyme N-acetyl-neuraminic lyase 分子名称: N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID, ... 著者 Campeotto, I, Phillips, S.E.V, Pearson, A.R. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 A Case Study for Twinned Data Analysis: Multiple Crystal Forms of the Enzyme N-Acetyl-Neuraminic Lyase To be Published
8AH9	De novo retro-aldolase RAbetaB-16.1 分子名称: BENZOIC ACID, RAbetaB-16.1 著者 Mittl, P, Oualb Chaib, A, Hilvert, D. 登録日 2022-07-21 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.747 Å) 主引用文献 Design and optimization of enzymatic activity in a de novo beta-barrel scaffold. Protein Sci., 31, 2022
5W6Q	Structural basis for recognition of artificial DNA by an evolved KlenTaq variant 分子名称: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
5W6K	Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P 分子名称: (1R)-1-[6-amino-5-(dihydroxyamino)-2-hydroxypyridin-3-yl]-1,4-anhydro-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-erythro-pentitol, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.339 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
2V20	Structure of a TEM-1 beta-lactamase insertant allosterically regulated by kanamycin and anions. Complex with sulfate. 分子名称: BETA-LACTAMASE TEM, SULFATE ION, ZINC ION 著者 Evrard, C, Barrios, H, Mathonet, P, Soumillion, P, Fastrez, J, Declercq, J.P. 登録日 2007-05-31 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Engineering an Allosteric Binding Site for Aminoglycosides Into Tem1-Beta-Lactamase. Chembiochem, 12, 2011
2V1Z	Structure of a TEM-1 beta-lactamase insertant allosterically regulated by kanamycin and anions. 分子名称: BETA-LACTAMASE TEM, ZINC ION 著者 Evrard, C, Barrios, H, Mathonet, P, Soumillion, P, Fastrez, J, Declercq, J.P. 登録日 2007-05-31 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Engineering an Allosteric Binding Site for Aminoglycosides Into Tem1-Beta-Lactamase. Chembiochem, 12, 2011
5EXU	Reversibly photoswitching protein Dathail, Ensemble refinement 分子名称: Reversibly photoswitching protein Dathail 著者 Close, D.W, Langan, P.S, Bradbury, A.R.M. 登録日 2015-11-24 公開日 2016-04-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Evolution and characterization of a new reversibly photoswitching chromogenic protein, Dathail. J.Mol.Biol., 428, 2016
4J9A	Engineered Digoxigenin binder DIG10.3 分子名称: DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.3 著者 Stoddard, B.L, Doyle, L.A. 登録日 2013-02-15 公開日 2013-06-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
6Z1K	A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.6 分子名称: 1,2-ETHANEDIOL, BH32.6 protein, CALCIUM ION, ... 著者 Levy, C.W. 登録日 2020-05-13 公開日 2021-08-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction. Nat.Chem., 14, 2022
6Z1L	A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.12 分子名称: 1,2-ETHANEDIOL, BH32.12 protein, PHOSPHATE ION 著者 Levy, C.W. 登録日 2020-05-13 公開日 2021-08-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction. Nat.Chem., 14, 2022
6XLR	The 1.23 Angstrom crystal structure of galactose oxidase variant with genetically incorporated Cl2-Tyr272 分子名称: ACETATE ION, CALCIUM ION, COPPER (II) ION, ... 著者 Liu, A, Li, J. 登録日 2020-06-29 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Formation of Monofluorinated Radical Cofactor in Galactose Oxidase through Copper-Mediated C-F Bond Scission. J.Am.Chem.Soc., 142, 2020
4J8T	Engineered Digoxigenin binder DIG10.2 分子名称: DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 著者 Stoddard, B.L, Doyle, L.A. 登録日 2013-02-14 公開日 2013-06-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
6AML	Phosphotriesterase variant S8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... 著者 Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. 登録日 2017-08-09 公開日 2018-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Phosphotriesterase variant S8 To Be Published
6UBH	Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide 分子名称: Erbin, SODIUM ION, peptide 著者 Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. 登録日 2019-09-11 公開日 2020-07-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021

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