PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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4NUE	Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor 分子名称: 1,2-ETHANEDIOL, 4-[(E)-(2-amino-4-hydroxy-3,5-dimethylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, Bromodomain-containing protein 4 著者 Plotnikov, A.N, Joshua, J, Zhou, M.-M. 登録日 2013-12-03 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains J.Med.Chem., 56, 2013
4G23	Crystal Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana with Mn 分子名称: Pentatricopeptide repeat-containing protein At2g32230, mitochondrial, ZINC ION 著者 Koutmos, M, Howard, M.J, Fierke, C.A. 登録日 2012-07-11 公開日 2012-09-26 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing. Proc.Natl.Acad.Sci.USA, 109, 2012
2YHG	Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Hehemann, J.H, Marsters, C, Boraston, A.B. 登録日 2011-04-30 公開日 2011-08-03 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism. Proteins, 79, 2011
4NCY	In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand 分子名称: 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... 著者 Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. 登録日 2013-10-25 公開日 2014-04-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
4TYH	Ternary complex of P38 and MK2 with a P38 inhibitor 分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide 著者 Cumming, J.G, Debreczeni, J.E, Edfeldt, F, Evertsson, F, Harrison, M, Holdgate, G, James, M, Lamont, S, Oldham, K, Sullivan, J.E, Wells, S. 登録日 2014-07-08 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Discovery of substrate selective, ATP-competitive P38 alpha MAP kinase inhibitors To Be Published
6AXE	Crystal structure of a malate synthase G from Mycobacterium marinum bound to acetyl CoA 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-09-06 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a malate synthase G from Mycobacterium marinum bound to acetyl CoA To Be Published
4U17	Swapped dimer of the human Fyn-SH2 domain 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Tyrosine-protein kinase Fyn 著者 Garcia-Pino, A, Huculeci, R, Lenaerts, T, van Nuland, N.A.J. 登録日 2014-07-15 公開日 2015-07-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Swapped dimer of the human Fyn-SH2 domain To Be Published
5R5G	PanDDA analysis group deposition -- Crystal Structure of human NUDT22 in complex with N13707a 分子名称: DIMETHYL SULFOXIDE, Uridine diphosphate glucose pyrophosphatase NUDT22, methyl 2-[(2~{S})-1-ethanoyl-3-oxidanylidene-piperazin-2-yl]ethanoate 著者 Diaz-Saez, L, Talon, R, Krojer, T, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Huber, K.V.M. 登録日 2020-02-28 公開日 2020-07-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 PanDDA analysis group deposition To Be Published
4U8I	Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A 分子名称: 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Qureshi, I.A, Chaudhary, R, Tanner, J.J. 登録日 2014-08-03 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
4M2L	Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in nucleotide-free form 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, SULFATE ION, ... 著者 Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. 登録日 2013-08-05 公開日 2014-03-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain 分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
3WBE	Rice Os3BGlu6 Beta-Glucosidase E178Q mutant in a covalent complex with Glc from GA4GE. 分子名称: Beta-glucosidase 6, GLYCEROL, alpha-D-glucopyranose 著者 Sansenya, S, Hua, Y, Cairns, J.R.K. 登録日 2013-05-14 公開日 2013-09-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Enzymatic and structural characterization of hydrolysis of gibberellin A4 glucosyl ester by a rice beta-d-glucosidase Arch.Biochem.Biophys., 537, 2013
1SIZ	Crystal structure of the [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus 分子名称: COBALT (III) ION, FE3-S4 CLUSTER, Ferredoxin 著者 Nielsen, M.S, Harris, P, Christensen, H.E.M. 登録日 2004-03-02 公開日 2004-05-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The 1.5 A Resolution Crystal Structure of [Fe3S4]-Ferredoxin from the Hyperthermophilic Archaeon Pyrococcus furiosus Biochemistry, 43, 2004
4U7J	Crystal structure of Argininosuccinate synthase from Mycobacterium thermoresistibile 分子名称: 1,2-ETHANEDIOL, Argininosuccinate synthase, CHLORIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-07-30 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of Argininosuccinate synthase from Mycobacterium thermoresistibile to be published
4MG4	Crystal structure of a putative phosphonomutase from Burkholderia cenocepacia J2315 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phosphonomutase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-08-28 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a putative phosphonomutase from Burkholderia cenocepacia J2315 TO BE PUBLISHED
3WIK	Crystal structure of the CK2alpha/compound10 complex 分子名称: Casein kinase II subunit alpha, N-[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-yl]acetamide 著者 Kinoshita, T, Nakaniwa, T, Sekiguchi, Y, Nakanishi, I. 登録日 2013-09-18 公開日 2014-11-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.995 Å) 主引用文献 Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening To be Published
6BX6	AMP-Activated protein kinase (AMPK) inhibition by SBI-0206965: alpha 2 kinase domain bound to SBI-0206965 分子名称: 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-N-methylbenzene-1-carboximidic acid, 5'-AMP-activated protein kinase catalytic subunit alpha-2 著者 Dite, T.A, Langendorf, C.G, Scott, J.W, Oakhill, J.S. 登録日 2017-12-17 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965. J. Biol. Chem., 293, 2018
4U8P	Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Y317A complexed with UDP 分子名称: 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Qureshi, I.A, Chaudhary, R, Tanner, J.J. 登録日 2014-08-03 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
3KRZ	Crystal Structure of the Thermostable NADH4-bound old yellow enzyme from Thermoanaerobacter pseudethanolicus E39 分子名称: 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, NADH:flavin oxidoreductase/NADH oxidase 著者 Adalbjornsson, B.V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2009-11-20 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme. Chembiochem, 11, 2010
4KLV	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 4-methylumbelliferyl phosphate 分子名称: 1,2-ETHANEDIOL, 4-methylumbelliferyl phosphate, SULFATE ION, ... 著者 Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2013-05-07 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem., 288, 2013
1SIS	SPATIAL STRUCTURE OF INSECTOTOXIN I5A BUTHUS EUPEUS BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (RUSSIAN) 分子名称: SCORPION INSECTOTOXIN I5A 著者 Arseniev, A.S, Kondakov, V.I, Lomize, A.L, Maiorov, V.N, Bystrov, V.F. 登録日 1993-11-11 公開日 1994-04-30 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Determination of the spatial structure of insectotoxin 15A from Buthus erpeus by (1)H-NMR spectroscopy data Bioorg.Khim., 17, 1991
1K64	NMR Structue of alpha-conotoxin EI 分子名称: alpha-conotoxin EI 著者 Park, K.H, Suk, J.E, Jacobsen, R, Gray, W.R, McIntosh, J.M, Han, K.H. 登録日 2001-10-15 公開日 2003-09-09 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor J.BIOL.CHEM., 276, 2001
4M16	Crystal Structure of the N-terminal Fic Domain of Bartonella effector protein (Bep); substrate of VirB T4SS (VirB-translocated Bep effector protein) from Bartonella sp. AR 15-3 分子名称: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-08-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4TZ8	Structure of human ATAD2 bromodomain bound to fragment inhibitor 分子名称: 2-amino-7,7-dimethyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[5,4-c]azepin-4-one, ATPase family AAA domain-containing protein 2, CHLORIDE ION, ... 著者 Harner, M.J, Chauder, B.A, Phan, J, Fesik, S.W. 登録日 2014-07-09 公開日 2014-10-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Fragment-Based Screening of the Bromodomain of ATAD2. J.Med.Chem., 57, 2014
6C5C	Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH 分子名称: 1,2-ETHANEDIOL, 3-dehydroquinate synthase, CHLORIDE ION, ... 著者 Michalska, K, Evdokimova, E, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-01-16 公開日 2018-01-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022

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