PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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6BVX	SFTI-HFRW-2 分子名称: Trypsin inhibitor 1 HFRW-2 著者 Schroeder, C.I. 登録日 2017-12-14 公開日 2018-12-19 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. J.Med.Chem., 61, 2018
6BVY	SFTI-HFRW-4 分子名称: Trypsin inhibitor 1 HFRW-4 著者 Schroeder, C.I, White, A. 登録日 2017-12-14 公開日 2018-04-18 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. J. Med. Chem., 61, 2018
6BVU	SFTI-HFRW-1 分子名称: Trypsin inhibitor 1 HFRW-1 著者 Schroeder, C.I. 登録日 2017-12-13 公開日 2018-12-19 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. J.Med.Chem., 61, 2018
1BJV	BETA-TRYPSIN COMPLEXED WITH APPU 分子名称: 1-(2-AMIDINOPHENYL)-3-(PHENOXYPHENYL)UREA, BETA-TRYPSIN, CALCIUM ION, ... 著者 Presnell, S, Patil, G, Mura, C, Jude, K, Conley, J, Kam, C, Bertrand, J, Powers, J, Williams, L. 登録日 1998-06-29 公開日 1998-12-02 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Oxyanion-mediated inhibition of serine proteases. Biochemistry, 37, 1998
1BJU	BETA-TRYPSIN COMPLEXED WITH ACPU 分子名称: 1-(4-AMIDINOPHENYL)-3-(4-CHLOROPHENYL)UREA, BETA-TRYPSIN, CALCIUM ION, ... 著者 Presnell, S, Patil, G, Mura, C, Jude, K, Conley, J, Kam, C, Bertrand, J, Powers, J, Williams, L. 登録日 1998-06-29 公開日 1998-12-02 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Oxyanion-mediated inhibition of serine proteases. Biochemistry, 37, 1998
1JV9	NMR Structure of BPTI Mutant G37A 分子名称: TRYPSIN INHIBITOR 著者 Battiste, J.L, Li, R, Woodward, C. 登録日 2001-08-28 公開日 2001-09-12 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility Biochemistry, 41, 2002
1JV8	NMR Structure of BPTI Mutant G37A 分子名称: TRYPSIN INHIBITOR 著者 Battiste, J.L, Li, R, Woodward, C. 登録日 2001-08-28 公開日 2001-09-12 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility Biochemistry, 41, 2002
6HX4	Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin 分子名称: Alpha-1-antitrypsin, Fab 1D9 heavy chain, Fab 1D9 light chain 著者 Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Lomas, D.A, Irving, J.A. 登録日 2018-10-15 公開日 2019-10-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin To Be Published
6I4V	Alpha-1-antitrypsin Queen's (K154N) variant 分子名称: 3-trimethylsilylpropane-1-sulfonic acid, Alpha-1-antitrypsin, GLYCINE 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-12 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
7A3M	Synergistic stabilization of a double mutant in CI2 from an in-cell library screen 分子名称: Subtilisin-chymotrypsin inhibitor-2A 著者 Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. 登録日 2020-08-18 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.01 Å) 主引用文献 Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
5NBV	Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations 分子名称: Alpha-1-antitrypsin, GLYCEROL 著者 Huntington, J.A, Pomowski, A, Johnson, D.J.D. 登録日 2017-03-02 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published
5NBU	Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations 分子名称: Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID 著者 Huntington, J.A, Pomowski, A, Johnson, D.J.D. 登録日 2017-03-02 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published
1YXA	Serpina3n, a murine orthologue of human antichymotrypsin 分子名称: serine (or cysteine) proteinase inhibitor, clade A, member 3N 著者 Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. 登録日 2005-02-20 公開日 2005-09-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005
1MBM	NSP4 proteinase from Equine Arteritis Virus 分子名称: chymotrypsin-like serine protease 著者 Barrette-Ng, I.H, Ng, K.K.-S, Mark, B.L, van Aken, D, Cherney, M.M, Garen, C, Kolodenko, Y, Gorbalenya, A.E, Snijder, E.J, James, M.N.G. 登録日 2002-08-03 公開日 2002-10-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Arterivirus nsp4: the smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole J.Biol.Chem., 277, 2002
1CIQ	COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64 分子名称: CHYMOTRYPSIN INHIBITOR 2 著者 Buckle, A.M, Fersht, A.R. 登録日 1995-10-02 公開日 1996-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
1CIR	COMPLEX OF TWO FRAGMENTS OF CI2 [(1-40)(DOT)(41-64)] 分子名称: CHYMOTRYPSIN INHIBITOR 2 著者 Davis, B.J, Fersht, A.R. 登録日 1995-10-02 公開日 1996-01-29 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
3DLW	Antichymotrypsin 分子名称: Alpha-1-antichymotrypsin 著者 Feil, S.C. 登録日 2008-06-29 公開日 2009-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
6EAV	Crystallographic structure of the cyclic heptapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 4(1) 2(1) 2 分子名称: CALCIUM ION, CYS-THR-LYS, Cationic trypsin 著者 Fernandes, J.C, Valadares, N.F, Freitas, S.M, Barbosa, J.A.R.G. 登録日 2018-08-03 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.391 Å) 主引用文献 Crystallographic structure of the cyclic heptapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 4(1) 2(1) 2 To Be Published
6EAW	Crystallographic structure of the cyclic heptapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21 分子名称: CALCIUM ION, CYS-THR-LYS-SER-ILE, Cationic trypsin, ... 著者 Fernandes, J.C, Valadares, N.F, Freitas, S.M, Barbosa, J.A.R.G. 登録日 2018-08-03 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.289 Å) 主引用文献 Crystallographic structure of the cyclic heptapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21 To Be Published
1TPP	THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS 分子名称: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPSIN, CALCIUM ION, ... 著者 Walter, J, Bode, W, Huber, R. 登録日 1982-09-27 公開日 1983-01-18 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Acta Crystallogr.,Sect.B, 39, 1983
9BOK	Crystal structure of reduced bovine trypsin, 50mM DTT-treated 分子名称: BENZAMIDINE, Cationic trypsin 著者 Zhou, D, Chen, L, Rose, J.P, Wang, B.C. 登録日 2024-05-03 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of reduced bovine trypsin, 50mM DTT-treated To Be Published
9BOM	Crystal structure of reduced bovine trypsin, 25mM DTT-treated 分子名称: BENZAMIDINE, Cationic trypsin 著者 Zhou, D, Chen, L, Rose, J.P, Wang, B.C. 登録日 2024-05-03 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of reduced bovine trypsin, 25mM DTT-treated To Be Published
6NTT	X-ray Crystal Structure of Soybean Trypsin Inhibitor (Kunitz) Complexed with 1,5-Disulfonyl Naphthalene 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Trypsin inhibitor A, naphthalene-1,5-disulfonic acid 著者 McPherson, A. 登録日 2019-01-30 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Lattice Interactions in Crystals of Soybean Trypsin Inhibitor (Kunitz) Produced by Inclusion of 1,5-Disulfonylnaphthalene Cryst.Growth Des., 19, 2019
8KDU	Crystal structure of trypsin with its substrate 分子名称: (2~{R})-2-benzamido-5-carbamimidamido-pentanoic acid, ARGININE, CALCIUM ION, ... 著者 Akbar, Z, Ahmad, M.S. 登録日 2023-08-10 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of trypsin with its substrate To Be Published
6EAX	Crystallographic structure of the cyclic hexapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21 分子名称: CALCIUM ION, CYS-THR-LYS-SER-ILE-CYS, Cationic trypsin, ... 著者 Fernandes, J.C, Valadares, N.F, Freitas, S.M, Barbosa, J.A.R.G. 登録日 2018-08-03 公開日 2019-08-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.189 Å) 主引用文献 Crystallographic structure of the cyclic hexapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21 To Be Published

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