PDB: 534 件ウェブページステータス検索Chemie searchBIRD

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2FO0	Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase 分子名称: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... 著者 Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. 登録日 2006-01-12 公開日 2006-03-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. Mol.Cell, 21, 2006
2EYY	CT10-Regulated Kinase isoform I 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2EYZ	CT10-Regulated Kinase isoform II 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2HCK	SRC FAMILY KINASE HCK-QUERCETIN COMPLEX 分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, CALCIUM ION, HEMATOPOETIC CELL KINASE HCK 著者 Sicheri, F, Moarefi, I, Kuriyan, J. 登録日 1997-02-25 公開日 1997-08-20 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the Src family tyrosine kinase Hck. Nature, 385, 1997
2K7A	Ensemble Structures of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase. 分子名称: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK 著者 Andreotti, A.H, Severin, A.J, Fulton, D.B. 登録日 2008-08-08 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
2H8H	Src kinase in complex with a quinazoline inhibitor 分子名称: N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src 著者 Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. 登録日 2006-06-07 公開日 2006-11-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006
2LQW	Solution structure of phosphorylated CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-16 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2K79	Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase 分子名称: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK 著者 Andreotti, A.H, Severin, A.J, Fulton, D.B. 登録日 2008-08-08 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
2LQN	Solution structure of CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-09 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012

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