PDB: 969 件ウェブページステータス検索Chemie searchBIRD

---

6Q81	Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state 分子名称: ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) 著者 Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. 登録日 2018-12-13 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
4DFY	Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop 分子名称: cAMP-dependent protein kinase catalytic subunit alpha 著者 Steichen, J.M, Kuchinskas, M, Yang, J, Taylor, S.S. 登録日 2012-01-24 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.997 Å) 主引用文献 Structural basis for the regulation of protein kinase a by activation loop phosphorylation. J.Biol.Chem., 287, 2012
4DFZ	Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 分子名称: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
4DH7	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, AMP-PNP and IP20' 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
4DH1	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with low Mg2+, ATP and IP20 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
6Q6H	Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D2 box class 分子名称: Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 13, ... 著者 Zhang, S, Barford, D. 登録日 2018-12-11 公開日 2019-09-11 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nat Commun, 10, 2019
6QJ7	Difluorophenyl diacylhydrazides: Potent inhibitors of Serum- and Glucocorticoid-inducible Kinase 1 (SGK1) 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ~{N}'-[(2~{S})-2-[3,5-bis(fluoranyl)phenyl]-2-oxidanyl-ethanoyl]-2-ethyl-3-methyl-4-oxidanyl-benzohydrazide 著者 Graedler, U. 登録日 2019-01-23 公開日 2020-02-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Difluorophenyl diacylhydrazides: Potent inhibitors of Serum- and Glucocorticoid-inducible Kinase 1 (SGK1) To Be Published
4DH8	Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, AMP-PNP and IP20 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
6Q6G	Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D1 box class 分子名称: Anaphase-promoting complex subunit 1,Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Zhang, S, Barford, D. 登録日 2018-12-11 公開日 2019-09-11 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nat Commun, 10, 2019
4DSZ	Crystal Structure of DPP-IV with Compound C2 分子名称: (2R)-4-[4-(3-methylphenyl)-1H-1,2,3-triazol-1-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine, Dipeptidyl peptidase 4 著者 Xiong, B, Zhu, L.R, Chen, D.Q, Zhao, Y.L, Jiang, F, Shen, J.K. 登録日 2012-02-20 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of DPP-IV with Compound C2 To be Published
4DG3	Crystal structure of R336A mutant of cAMP-dependent protein kinase with unphosphorylated turn motif. 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Steichen, J.M, Yang, J, Taylor, S.S. 登録日 2012-01-24 公開日 2013-02-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Turn motif phosphorylation regulates processing of cAMP-dependent protein kinase To be Published
4DH5	Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ADP, Phosphate, and IP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
4DFX	Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP 分子名称: GLYCEROL, MAGNESIUM ION, MYRISTIC ACID, ... 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
4DIN	Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S. 登録日 2012-01-31 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Localization and quaternary structure of the PKA RI Beta holoenzyme Proc.Natl.Acad.Sci.USA, 109, 2012
4DTC	Crystal Structure of DPP-IV with Compound C5 分子名称: Dipeptidyl peptidase 4, N-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butyl]-3'-(trifluoromethyl)biphenyl-4-carboxamide 著者 Xiong, B, Zhu, L.R, Chen, D.Q, Zhao, Y.L, Jiang, F, Shen, J.K. 登録日 2012-02-21 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of DPP-IV with Compound C5 To be Published
4DG0	Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP 分子名称: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
4DG2	Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 分子名称: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
4DH3	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ATP and IP20 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
4DSA	Crystal Structure of DPP-IV with Compound C1 分子名称: 4-[({[(2R)-2-amino-3-(2,4,5-trifluorophenyl)propyl]sulfamoyl}amino)methyl]benzenesulfonamide, Dipeptidyl peptidase 4 著者 Xiong, B, Zhu, L.R, Chen, D.Q, Zhao, Y.L, Jiang, F, Shen, J.K. 登録日 2012-02-18 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal Structure of DPP-IV with Compound C1 To be Published
6EH2	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp032 and AMP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-09-12 公開日 2018-10-10 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
6EH3	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and RKp190 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor, ~{N}-[2-[(phenylmethyl)amino]ethyl]isoquinoline-5-sulfonamide 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-09-12 公開日 2018-10-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and RKp190 To be published
6E87	Crystal structure of ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition 分子名称: Cysteine dioxygenase type 1, FE (II) ION, GLYCEROL, ... 著者 Liu, A, Li, J. 登録日 2018-07-27 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry, 58, 2019
6ERU	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compound RKp120 分子名称: UPF0418 protein FAM164A, cAMP-dependent protein kinase catalytic subunit alpha 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-10-19 公開日 2018-10-31 最終更新日 2020-07-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
6EGW	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp017 and RKp117 分子名称: [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, alpha-D-ribofuranose, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-09-12 公開日 2018-10-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
6EM7	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, UPF0418 protein FAM164A, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-10-01 公開日 2018-10-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.238 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019

<15161718192021222324252627282930>