PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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7EUO	The structure of formyl peptide receptor 1 in complex with Gi and peptide agonist fMLF 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q. 登録日 2021-05-18 公開日 2022-05-25 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nat Commun, 13, 2022
6VB5	HLA-B*15:02 complexed with a synthetic peptide 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... 著者 Schutte, R.J, Li, D, Ostrov, D.A. 登録日 2019-12-18 公開日 2020-11-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 HLA-B*15:02 complexed with a synthetic peptide To Be Published
1BQO	DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS 分子名称: 1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC ACID HYDROXYAMIDE, CALCIUM ION, STROMELYSIN-1, ... 著者 Pikul, S, Dunham, K.L.M, Almstead, N.G, De, B, Natchus, M.G, Anastasio, M.V, Mcphail, S.J, Snider, C.E, Taiwo, Y.O, Rydel, T.J, Dunaway, C.M, Gu, F, Mieling, G.E. 登録日 1998-08-17 公開日 1999-08-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of potent, achiral matrix metalloproteinase inhibitors. J.Med.Chem., 41, 1998
5DR7	Endothiapepsin in complex with fragment 311 分子名称: (2R)-3-cyclopropyl-2-(4-methoxyphenyl)-1,3-thiazolidin-4-one, ACETATE ION, Endothiapepsin, ... 著者 Heine, A, Schiebel, J, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.234 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4OK5	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 9 [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
6G56	Apo-structure of the alanine racemase from Staphylococcus aureus 分子名称: Alanine racemase 1, GLYCEROL, SULFATE ION 著者 Hoegl, A, Sieber, S.A, Schneider, S. 登録日 2018-03-29 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics. Nat Chem, 10, 2018
5DSQ	Structure of CO2 released apo-form of human carbonic anhydrase II with 3 min warming 分子名称: Carbonic anhydrase 2, GLYCEROL 著者 Kim, C.U, Park, S.Y, McKenna, R. 登録日 2015-09-17 公開日 2016-05-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Tracking solvent and protein movement during CO2 release in carbonic anhydrase II crystals Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5DJV	Crystal structure of human FPPS in complex with biaryl compound 8e 分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-10-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
5DJR	Crystal structure of human FPPS in complex with biaryl compound 6 分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
1BQ3	SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE IN COMPLEX WITH INOSITOL HEXAKISPHOSPHATE 分子名称: INOSITOL HEXAKISPHOSPHATE, PROTEIN (PHOSPHOGLYCERATE MUTASE 1), SULFATE ION 著者 Rigden, D.J, Phillips, S.E.V, Fothergill-Gilmore, L.A. 登録日 1998-08-20 公開日 1998-08-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis. J.Mol.Biol., 289, 1999
1BX7	HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS 分子名称: HIRUSTASIN, SULFATE ION 著者 Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E. 登録日 1998-10-14 公開日 1999-04-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors. Structure Fold.Des., 7, 1999
4OYD	Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein 分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BHRF1, Computationally designed Inhibitor 著者 Shen, B, Procko, E, Baker, D, Stoddard, B. 登録日 2014-02-11 公開日 2014-07-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells. Cell, 157, 2014
1ZTL	Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide 分子名称: Coagulation factor XI, N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-2-{6-OXO-5-[(QUINOLIN-8-YLMETHYL)-AMINO]-2-M-TOLYL-6H-PYRIMIDIN-1-YL}-ACETAMIDE, SULFATE ION 著者 Nagafuji, P, Jin, L, Rynkiewicz, M, Quinn, J, Bibbins, F, Meyers, H, Babine, R, Strickler, J.E, Abdel-Meguid, S.S. 登録日 2005-05-27 公開日 2006-05-09 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Pyrimidinone Inhibitors of a Thrombolytic Protease To be Published
1BVQ	THREE-DIMENSIONAL STRUCTURE OF 4-HYDROXYBENZOYL COA THIOESTERASE FROM PSEUDOMONAS SP. STRAIN CBS-3. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PROTEIN (4-HYDROXYBENZOYL COA THIOESTERASE) 著者 Holden, H.M, Benning, M.M, Dunaway-Mariano, D. 登録日 1998-09-16 公開日 1998-09-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The three-dimensional structure of 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. Strain CBS-3. J.Biol.Chem., 273, 1998
4ZTN	Irak4-inhibitor co-structure 分子名称: 5-(1,3-benzothiazol-2-yl)-2-(morpholin-4-yl)-6-[(3R)-piperidin-3-ylamino]pyrimidin-4(3H)-one, Interleukin-1 receptor-associated kinase 4 著者 Fischmann, T.O. 登録日 2015-05-14 公開日 2015-09-02 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors. Acs Med.Chem.Lett., 6, 2015
9JGG	Solution structure of Murinotoxin-1 分子名称: Murinotoxin-1 著者 Lushpa, V.A, Kuzmenkov, A.I, Deyev, Y.A, Iunusova, V.A, Bocharov, E.V, Vassilevski, A.A. 登録日 2024-09-07 公開日 2025-09-10 最終更新日 2025-10-29 実験手法 SOLUTION NMR 主引用文献 Spider venom peptides with unique fold selectively block Shaker-type potassium channels. Cell.Mol.Life Sci., 82, 2025
5DXA	Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R460) 分子名称: GLYCEROL, Histone-arginine methyltransferase CARM1, SINEFUNGIN, ... 著者 Boriack-Sjodin, P.A. 登録日 2015-09-23 公開日 2015-11-25 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates. Acs Chem.Biol., 11, 2016
4OOS	Crystal structure of P domain from norovirus strain NSW0514 分子名称: 1,2-ETHANEDIOL, VP1 著者 Singh, B.K, Hansman, G.S. 登録日 2014-02-04 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Human noroviruses' fondness for histo-blood group antigens. J.Virol., 89, 2015
4OQ3	Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction 分子名称: 1-(5-chloro-2-methylphenyl)-5-(3-chlorophenyl)-2-(3-methylphenyl)-1H-imidazole-4-carboxylic acid, E3 ubiquitin-protein ligase Mdm2 著者 Kallen, J. 登録日 2014-02-07 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction. Bioorg.Med.Chem.Lett., 24, 2014
1C2A	CRYSTAL STRUCTURE OF BARLEY BBI 分子名称: BOWMAN-BIRK TRYPSIN INHIBITOR 著者 Song, H.K, Kim, Y.S, Yang, J.K, Moon, J, Lee, J.Y, Suh, S.W. 登録日 1999-07-23 公開日 1999-12-29 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a 16 kDa double-headed Bowman-Birk trypsin inhibitor from barley seeds at 1.9 A resolution. J.Mol.Biol., 293, 1999
7U35	Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with ADP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, UDP-N-acetylmuramoylalanine--D-glutamate ligase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-02-25 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with ADP to be published
3L4U	Crystal complex of N-terminal Human Maltase-Glucoamylase with de-O-sulfonated kotalanol 分子名称: (2R,3S,4S)-1-[(2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl]-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sim, L, Rose, D.R. 登録日 2009-12-21 公開日 2010-02-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
8TQM	Cryo-EM structure of E3 ubiquitin ligase Doa10 from Saccharomyces cerevisiae 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ERAD-associated E3 ubiquitin-protein ligase DOA10, ... 著者 Park, E, Itskanov, S.I. 登録日 2023-08-07 公開日 2024-03-13 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10. Nat Commun, 15, 2024
5GNU	the structure of mini-MFN1 apo 分子名称: Mitofusin-1 著者 Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J. 登録日 2016-07-25 公開日 2016-11-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (4.113 Å) 主引用文献 BDLP-like folding of Mitofusin 1 To Be Published
9JNB	Crystal Structure of SME-1 E166A mutant in complex with imipenem 分子名称: Imipenem, beta-lactamase 著者 Dhankhar, K, Hazra, S. 登録日 2024-09-23 公開日 2025-10-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of SME-1 E166A mutant in complex with imipenem To Be Published

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