7EUO

The structure of formyl peptide receptor 1 in complex with Gi and peptide agonist fMLF

Summary for 7EUO

• Entry DOI: 10.2210/pdb7euo/pdb
• EMDB information: 31323
• Descriptor: fMet-Leu-Phe receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
• Functional Keywords: formyl peptide receptor 1, gi complex, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 159470.87

Authors

Wang, X.K.,Chen, G.,Liao, Q.W.,Du, Y.,Hu, H.L.,Ye, D.Q. (deposition date: 2021-05-18, release date: 2022-05-25, Last modification date: 2022-12-07)

• Primary citation: Chen, G.,Wang, X.,Liao, Q.,Ge, Y.,Jiao, H.,Chen, Q.,Liu, Y.,Lyu, W.,Zhu, L.,van Zundert, G.C.P.,Robertson, M.J.,Skiniotis, G.,Du, Y.,Hu, H.,Ye, R.D.; Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.; Nat Commun, 13:5232-5232, 2022; PubMed: 36064945; DOI: 10.1038/s41467-022-32822-y

Experimental method

ELECTRON MICROSCOPY (2.9 Å)