PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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5UOG	Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in apo form 分子名称: NADPH-dependent glyoxylate/hydroxypyruvate reductase, SULFATE ION 著者 Shabalin, I.G, Handing, K.B, Gasiorowska, O.A, Cooper, D.R, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2017-01-31 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57, 2018
6MBJ	SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, P21 Crystal Form 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... 著者 Horton, J.R, Dai, S, Cheng, X. 登録日 2018-08-30 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature, 565, 2019
7S3I	Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) 分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Belousoff, M.J, Piper, S.J, Danev, R. 登録日 2021-09-07 公開日 2022-01-05 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Structural and functional diversity among agonist-bound states of the GLP-1 receptor. Nat.Chem.Biol., 18, 2022
2GT1	E. coli heptosyltransferase WaaC. 分子名称: Lipopolysaccharide heptosyltransferase-1 著者 Grizot, S, Salem, M, Vongsouthi, V, Durand, L, Moreau, F, Dohi, H, Vincent, S, Escaich, S, Ducruix, A. 登録日 2006-04-27 公開日 2007-05-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Escherichia coli Heptosyltransferase WaaC: Binary Complexes with ADP AND ADP-2-deoxy-2-fluoro Heptose. J.Mol.Biol., 363, 2006
6KH4	Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes 分子名称: FE (III) ION, Ferritin, NICKEL (II) ION 著者 Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. 登録日 2019-07-12 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020
5UNX	Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)ethyl)benzonitrile 分子名称: 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[2-(methylamino)ethyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
5UOD	Structure of bovine endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile 分子名称: 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
5UO0	Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile 分子名称: 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2S)-2-(methylamino)propyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
5UNS	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-({3-ethyl-5-[(methylamino)methyl]phenoxy}methyl)quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
5UO3	Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile 分子名称: 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
4KTD	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate 分子名称: GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ... 著者 Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T. 登録日 2013-05-20 公開日 2014-02-05 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
1JY9	MINIMIZED AVERAGE STRUCTURE OF DP-TT2 分子名称: DP-TT2 著者 Stanger, H.E, Syud, F.A, Espinosa, J.F, Giriat, I, Muir, T, Gellman, S.H. 登録日 2001-09-11 公開日 2001-09-19 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure. Proc.Natl.Acad.Sci.USA, 98, 2001
3KUK	Trapping of an oxocarbenium ion intermediate in UP crystals 分子名称: 2'-DEOXYURIDINE, SULFATE ION, Uridine phosphorylase 著者 Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. 登録日 2009-11-27 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.783 Å) 主引用文献 Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
3KVY	Trapping of an oxocarbenium ion intermediate in UP crystals 分子名称: 1,4-anhydro-D-erythro-pent-1-enitol, SULFATE ION, URACIL, ... 著者 Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. 登録日 2009-11-30 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
4D4Q	Crystal Structure of Kti13/AtS1 分子名称: PROTEIN ATS1 著者 Glatt, S, Mueller, C.W. 登録日 2014-10-30 公開日 2015-01-14 最終更新日 2017-03-29 実験手法 X-RAY DIFFRACTION (2.395 Å) 主引用文献 Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2. Structure, 23, 2015
2H1F	E. coli heptosyltransferase WaaC with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide heptosyltransferase-1 著者 Grizot, S, Salem, M, Vongsouthi, V, Durand, L, Moreau, F, Dohi, H, Vincent, S, Escaich, S, Ducruix, A. 登録日 2006-05-16 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the Escherichia coli heptosyltransferase WaaC: binary complexes with ADP and ADP-2-deoxy-2-fluoro heptose. J.Mol.Biol., 363, 2006
3L0R	Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata 分子名称: CHLORIDE ION, Cystatin-2, GLYCEROL 著者 Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M. 登録日 2009-12-10 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata Biochem.J., 429, 2010
4ZZE	Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with panose 分子名称: CHLORIDE ION, MAGNESIUM ION, Sugar binding protein of ABC transporter system, ... 著者 Fredslund, F, Ejby, M, Andersen, J.M, Slotboom, D.J, Hachem, M.A. 登録日 2015-05-22 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates. J. Biol. Chem., 291, 2016
4ZZA	Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with raffinose, selenomethionine derivative 分子名称: Sugar binding protein of ABC transporter system, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose 著者 Fredslund, F, Ejby, M, Andersen, J.M, Slotboom, D.J, Abou Hachem, M. 登録日 2015-05-22 公開日 2016-06-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates. J. Biol. Chem., 291, 2016
5A8Z	Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(4R)-7-methyl-2,5-bis(oxidanylidene)-1-[3-(trifluoromethyl)phenyl]-3,4,6,8-tetrahydropyrimido[4,5-d]pyridazin-4-yl]benzenecarbonitrile, Neutrophil elastase, ... 著者 von Nussbaum, F, Li, V.M, Meibom, D, Anlauf, S, Bechem, M, Delbeck, M, Gerisch, M, Harrenga, A, Karthaus, D, Lang, D, Lustig, K, Mittendorf, J, Schaefer, M, Schaefer, S, Schamberger, J. 登録日 2015-07-17 公開日 2016-08-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model. ChemMedChem, 11, 2016
6M5W	Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S. 登録日 2020-03-11 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate. Iscience, 24, 2021
5FWT	Wnt modulator Kremen crystal form I at 2.10A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, KREMEN PROTEIN 1, ... 著者 Zebisch, M, Jackson, V.A, Jones, E.Y. 登録日 2016-02-21 公開日 2016-07-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf Structure, 24, 2016
6BAS	Crystal structure of Thermus thermophilus Rod shape determining protein RodA D255A mutant (Q5SIX3_THET8) 分子名称: CHLORIDE ION, Peptidoglycan glycosyltransferase RodA 著者 Sjodt, M, Brock, K, Dobihal, G, Rohs, P.D.A, Green, A.G, Hopf, T.A, Meeske, A.J, Marks, D.S, Bernhardt, T.G, Rudner, D.Z, Kruse, A.C. 登録日 2017-10-15 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.194 Å) 主引用文献 Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis. Nature, 556, 2018
1XGV	Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix 分子名称: Isocitrate dehydrogenase 著者 Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. 登録日 2004-09-17 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol., 345, 2005
6KH1	Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes 分子名称: FE (III) ION, Ferritin, NICKEL (II) ION 著者 Gu, C, Chen, H, Wang, Y, Zhang, T, Whang, H, Zhao, G. 登録日 2019-07-12 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020

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