PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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4D9I	Crystal structure of holo Diaminopropionate ammonia lyase from Escherichia coli 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Diaminopropionate ammonia-lyase 著者 Bisht, S, Rajaram, V, Bharath, S.R, Murthy, M.R.N. 登録日 2012-01-11 公開日 2012-04-25 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and Catalysis J.Biol.Chem., 287, 2012
5T98	Crystal structure of BuGH2Awt 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside Hydrolase 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-09-09 公開日 2017-09-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
7GAN	PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z56767614 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... 著者 Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-08-10 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5TA1	Crystal structure of BuGH86wt 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-09-09 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
4MQ9	Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 分子名称: (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. 登録日 2013-09-16 公開日 2014-05-07 最終更新日 2025-08-13 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
1IDB	Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere 分子名称: (2R,4S)-N-tert-butyl-1-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutyl]-4-(pyridin-4-ylsulfonyl)piperidine-2-carboxamide, Protease 著者 Tong, L, Anderson, P.C. 登録日 1994-10-19 公開日 1995-01-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere. Structure, 3, 1995
5OTL	The crystal structure of CK2alpha in complex with compound 29 分子名称: ACETATE ION, Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER, ... 著者 Brear, P, De Fusco, C, Iegre, J, Yoshida, M, Mitchell, S, Rossmann, M, Carro, L, Sore, H, Hyvonen, M, Spring, D. 登録日 2017-08-22 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Second-generation CK2 alpha inhibitors targeting the alpha D pocket. Chem Sci, 9, 2018
6HWD	Yeast 20S proteasome beta2-G45A mutant in complex with bortezomib 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
5T9N	Structure of rabbit RyR1 (Ca2+-only dataset, class 2) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-09 公開日 2016-10-12 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
7GA8	PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198158918 分子名称: 1,2-ETHANEDIOL, 1H-indazole-3-carbonitrile, CHLORIDE ION, ... 著者 Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-08-10 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5YQW	Structure and function of a novel periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... 著者 Suginta, W, Sritho, N, Ranok, A, Kitaoku, Y, Bulmer, D.M, van den Berg, B, Fukamizo, T. 登録日 2017-11-08 公開日 2018-02-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structure and function of a novel periplasmic chitooligosaccharide-binding protein from marineVibriobacteria. J. Biol. Chem., 293, 2018
7HJH	PanDDA analysis group deposition -- Crystal structure of ABLE in complex with ZINC000000159056 分子名称: 1-methyl-5-phenyl-1H-pyrazole-4-carboxylic acid, De novo designed ABLE protein 著者 Correy, G.J, Fraser, J.S. 登録日 2024-10-08 公開日 2025-08-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Fragment screen against ABLE To be published
7GAG	PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z198195770 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... 著者 Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-08-10 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7GAO	PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z57450788 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... 著者 Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-08-10 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 PanDDA analysis group deposition To Be Published
8T6G	Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors 分子名称: (1S)-1-{6-[(1S)-1-amino-1,3-dihydrospiro[indene-2,4'-piperidin]-1'-yl]-3-(3,4-dihydro-1,5-naphthyridin-1(2H)-yl)-1H-pyrazolo[3,4-b]pyrazin-5-yl}ethan-1-ol, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 著者 Tang, Y, Nugyen, V, Wilbur, J.D. 登録日 2023-06-15 公開日 2023-10-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors. J.Med.Chem., 66, 2023
3I85	The Crystal Structure of Human EMMPRIN N-terminal Domain 1 分子名称: Cervical EMMPRIN 著者 Luo, J, Gilliland, G.L. 登録日 2009-07-09 公開日 2009-10-06 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping. Proteins, 77, 2009
1I8U	FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A 分子名称: CALCIUM ION, ENDO-1,4-BETA-XYLANASE A 著者 Notenboom, V, Boraston, A.B, Warren, R.A.J, Kilburn, D.G, Rose, D.R. 登録日 2001-03-16 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms. Biochemistry, 40, 2001
5YQ8	Crystal structure of retroviral protease-like domain of Ddi1 from Leishmania major 分子名称: DNA-damage inducible protein DDI1-like protein 著者 Suguna, K, Kumar, S. 登録日 2017-11-06 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of the retroviral protease-like domain of a protozoal DNA damage-inducible 1 protein. FEBS Open Bio, 8, 2018
5D5C	In meso in situ serial X-ray crystallography structure of lysozyme at 100 K 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ACETIC ACID, BROMIDE ION, ... 著者 Huang, C.-Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M. 登録日 2015-08-10 公開日 2016-01-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Acta Crystallogr D Struct Biol, 72, 2016
6UIJ	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with S-{5-[(3-aminopropyl)amino]pentyl} thioacetate 分子名称: 5-[(3-aminopropyl)amino]pentane-1-thiol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-10-01 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
7HJD	PanDDA analysis group deposition -- Crystal structure of ABLE in complex with ZINC000000164504 分子名称: 1,3-benzodioxol-5-ol, De novo designed ABLE protein 著者 Correy, G.J, Fraser, J.S. 登録日 2024-10-08 公開日 2025-08-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Fragment screen against ABLE To be published
6HTR	Yeast 20S proteasome with human beta2c (S171G) in complex with 13 分子名称: (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, MAGNESIUM ION, PROTEASOME SUBUNIT ALPHA TYPE-1, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-04 公開日 2019-01-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
7ZO5	L1 metallo-beta-lactamase in complex with a mecillinam degradation product 分子名称: (2~{R},4~{S})-2-[(1~{R})-2-(azepan-1-yl)-1-formamido-2-oxidanylidene-ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2022-04-24 公開日 2023-03-08 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products. J.Biol.Chem., 299, 2023
5TAW	Structure of rabbit RyR1 (ryanodine dataset, all particles) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
7ZO6	L1 metallo-beta-lactamase in complex with hydrolysed cefoxitin 分子名称: (2~{R},5~{S})-5-(aminocarbonyloxymethyl)-2-[(1~{S})-1-methoxy-2-oxidanyl-2-oxidanylidene-1-(2-thiophen-2-ylethanoylamino)ethyl]-5,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2022-04-24 公開日 2023-03-08 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products. J.Biol.Chem., 299, 2023

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