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7D0E
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BU of 7d0e by Molmil
Crystal structure of FIP200 Claw/p-CCPG1 FIR2
分子名称: 3-(2-hydroxyethyloxy)-2-[2-(2-hydroxyethyloxy)ethoxymethyl]-2-(2-hydroxyethyloxymethyl)propan-1-ol, Cell cycle progression protein 1 FIR2, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-09
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
7CZG
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Crystal structure of FIP200 Claw domain apo form
分子名称: DI(HYDROXYETHYL)ETHER, RB1-inducible coiled-coil protein 1
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-08
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
6MYP
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BU of 6myp by Molmil
Avian mitochondrial complex II with TTFA (thenoyltrifluoroacetone) bound
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 4,4,4-TRIFLUORO-1-THIEN-2-YLBUTANE-1,3-DIONE, BICARBONATE ION, ...
著者Berry, E.A, Huang, L.-S.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
7CZM
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BU of 7czm by Molmil
Crystal structure of FIP200 Claw/p-OPtineurin LIR complex
分子名称: CHLORIDE ION, GLYCEROL, Optineurin LIR, ...
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-09
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
6SVC
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BU of 6svc by Molmil
Protein allostery of the WW domain at atomic resolution: apo structure
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
登録日2019-09-18
公開日2020-09-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
6MYT
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BU of 6myt by Molmil
Avian mitochondrial complex II with Atpenin A5 bound, sidechain in pocket
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE, DI(HYDROXYETHYL)ETHER, ...
著者Berry, E.A, Huang, L.-S.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
4DXT
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BU of 4dxt by Molmil
Human SUN2 (AA 522-717)
分子名称: POTASSIUM ION, SUN domain-containing protein 2
著者Sosa, B, Schwartz, T.U.
登録日2012-02-28
公開日2012-06-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins.
Cell(Cambridge,Mass.), 149, 2012
7L20
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BU of 7l20 by Molmil
Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt.
分子名称: 16S rRNA mitochondrial, 39 S P-site finger, 39S ribosomal protein L10, ...
著者Agrawal, E, Koripella, R.
登録日2020-12-15
公開日2021-05-12
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.
Nat Commun, 12, 2021
8OIR
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BU of 8oir by Molmil
55S human mitochondrial ribosome with mtRF1 and P-site tRNA
分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
著者Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
登録日2023-03-23
公開日2023-06-14
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
3KAB
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BU of 3kab by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: 6-methyl-1H-indole-2-carboxylic acid, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ...
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
1NMW
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BU of 1nmw by Molmil
Solution structure of the PPIase domain of human Pin1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION
著者Bayer, E, Goettsch, S, Mueller, J.W, Griewel, B, Guiberman, E, Mayr, L, Bayer, P.
登録日2003-01-12
公開日2003-07-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING.
J.Biol.Chem., 278, 2003
3KAD
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BU of 3kad by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: 3-(1H-benzimidazol-2-yl)-N-(3-phenylpropanoyl)-D-alanine, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
6MYU
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BU of 6myu by Molmil
Avian mitochondrial complex II crystallized in the presence of HQNO
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ...
著者Berry, E.A, Huang, L.-S.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
6MYO
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BU of 6myo by Molmil
Avian mitochondrial complex II with flutolanyl bound
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ...
著者Berry, E.A, Huang, L.-S.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
3KAF
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BU of 3kaf by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: 3-(1H-benzimidazol-2-yl)-N-(1-benzothiophen-2-ylcarbonyl)-D-alanine, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
3JYJ
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BU of 3jyj by Molmil
Structure-Based Design of Novel PIN1 Inhibitors (II)
分子名称: (2R,4E)-2-[(naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Greasley, S.E, Ferre, R.A.
登録日2009-09-21
公開日2010-04-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure-based design of novel human Pin1 inhibitors (II).
Bioorg.Med.Chem.Lett., 20, 2010
1NMV
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BU of 1nmv by Molmil
Solution structure of human Pin1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Bayer, E, Goettsch, S, Mueller, J.W, Griewel, B, Guiberman, E, Mayr, L, Bayer, P.
登録日2003-01-11
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING.
J.Biol.Chem., 278, 2003
6MYS
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BU of 6mys by Molmil
Avian mitochondrial complex II with Atpenin A5 bound, sidechain outside
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE, FE2/S2 (INORGANIC) CLUSTER, ...
著者Berry, E.A, Huang, L.-S.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
3KAC
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BU of 3kac by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: 3-(1H-benzimidazol-2-yl)propanoic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
3KAH
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BU of 3kah by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: 3-(1H-benzimidazol-2-yl)-N-[(1-methyl-3-phenyl-1H-pyrazol-5-yl)carbonyl]-D-alanine, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
3KAI
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BU of 3kai by Molmil
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
分子名称: (2R)-2-[(2-methyl-5-phenyl-pyrazol-3-yl)carbonylamino]-3-naphthalen-2-yl-propanoic acid, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D.
登録日2009-10-19
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
1MV0
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BU of 1mv0 by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
分子名称: Myc box-dependent-interacting protein 1, Myc proto-oncogene protein
著者Pineda-Lucena, A, Arrowsmith, C.H.
登録日2002-09-24
公開日2003-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
6TP5
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BU of 6tp5 by Molmil
Crystal structure of human Transmembrane prolyl 4-hydroxylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Myllykoski, M, Sutinen, A, Koski, M.K, Kallio, J.P, Raasakka, A, Myllyharju, J, Wierenga, R.K, Koivunen, P.
登録日2019-12-12
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains.
J.Biol.Chem., 296, 2020
4JXM
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BU of 4jxm by Molmil
Crystal structure of RRP9 WD40 repeats
分子名称: U3 small nucleolar RNA-interacting protein 2, UNKNOWN ATOM OR ION
著者Wu, X, Tempel, W, Xu, C, El Bakkouri, M, He, H, Seitova, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-03-28
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of RRP9 WD40 repeats
To be Published
3V6A
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BU of 3v6a by Molmil
Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules
分子名称: Apoptosis inhibitor 5
著者Lee, B.I, Han, B.G, Lee, S.J.
登録日2011-12-19
公開日2012-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules.
J.Biol.Chem., 287, 2012

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