PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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7P0W	Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), ... 著者 Coste, F, Goffinont, S, Flament, D, Castaing, B. 登録日 2021-06-30 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
4MFC	Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-27 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4LUG	Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana 分子名称: Inorganic pyrophosphatase, SODIUM ION 著者 Grzechowiak, M, Ruszkowski, M, Sikorski, M, Jaskolski, M. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal structure of Inorganic pyrophosphatase PPA1 from Arabidopsis thaliana To be Published
4Q53	Crystal structure of a DUF4783 family protein (BACUNI_04292) from Bacteroides uniformis ATCC 8492 at 1.27 A resolution 分子名称: 1,2-ETHANEDIOL, 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-04-15 公開日 2014-07-16 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Crystal structure of a hypothetical protein (BACUNI_04292) from Bacteroides uniformis ATCC 8492 at 1.27 A resolution To be published
8EMK	Crystal structure of HLA-B*35:01-NP3 epitope from 1957 H2N2 influenza strain 分子名称: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP3 epitope, ... 著者 Littler, D.R, Rossjohn, J. 登録日 2022-09-27 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.66523 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
4Q2P	NHERF3 PDZ2 in Complex with a Phage-Derived Peptide 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3 著者 Appleton, B.A, Wiesmann, C. 登録日 2014-04-09 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014
4Q39	PylD in complex with pyrrolysine and NADH 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... 著者 Quitterer, F, Beck, P, Bacher, A, Groll, M. 登録日 2014-04-11 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Formation of Pyrroline and Tetrahydropyridine Rings in Amino Acids Catalyzed by Pyrrolysine Synthase (PylD). Angew.Chem.Int.Ed.Engl., 53, 2014
4LI5	EGFR-K IN COMPLEX WITH N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl] Prop-2-enamide 分子名称: Epidermal growth factor receptor, N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide, SODIUM ION 著者 Debreczeni, J.E, Seiffert, G.B, Kiefersauer, R, Augustin, M, Nagel, S, Ward, R, Anderton, M, Ashton, S, Bethel, P, Box, M, Butterworth, S, Colclough, N, Chroley, C, Chuaqui, C, Cross, D, Eberlein, C, Finlay, R, Hill, G, Grist, M, Klinowska, T, Lane, C, Martin, S, Orme, J, Smith, P, Wang, F, Waring, M. 登録日 2013-07-02 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR). J.Med.Chem., 56, 2013
4KXY	Human transketolase in complex with ThDP analogue (R)-2-(1,2-dihydroxyethyl)-3-deaza-ThDP 分子名称: 1,2-ETHANEDIOL, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[(1R)-1,2-dihydroxyethyl]-3-methylthiophen-2-yl}ethyl trihydrogen diphosphate, CALCIUM ION, ... 著者 Neumann, P, Luedtke, S, Erixon, K.M, Leeper, F, Kluger, R, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
4LH7	Crystal structure of a LigA inhibitor 分子名称: 4-aminothieno[3,2-c]pyridine-2,7-dicarboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ... 著者 Boriack-Sjodin, P.A, Prince, D.B. 登録日 2013-06-30 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification through structure-based methods of a bacterial NAD(+)-dependent DNA ligase inhibitor that avoids known resistance mutations. Bioorg.Med.Chem.Lett., 24, 2014
3NU5	Crystal Structure of HIV-1 Protease Mutant I50V with Antiviral Drug Amprenavir 分子名称: ACETATE ION, CHLORIDE ION, SODIUM ION, ... 著者 Wang, Y.-F, Shen, C.H, Weber, I.T. 登録日 2010-07-06 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters. Febs J., 277, 2010
4L9S	Crystal Structure of H-Ras G12C, GDP-bound 分子名称: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-06-18 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.606 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4PVE	Wild-type Phl p 4.0202, a glucose dehydrogenase 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, ... 著者 Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. 登録日 2014-03-17 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
4PVP	Crystal structure of malonate-bound human L-asparaginase protein 分子名称: Isoaspartyl peptidase/L-asparaginase, MALONATE ION, SODIUM ION 著者 Nomme, J, Lavie, A. 登録日 2014-03-18 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of apo and product-bound human L-asparaginase: insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry, 51, 2012
1WQM	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
1WQO	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
1WQP	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
1WQR	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
1WQN	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
1WQQ	CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: CHLORIDE ION, LYSOZYME, SODIUM ION 著者 Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. 登録日 1998-02-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
4LDO	Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, Camelid Antibody Fragment, L-EPINEPHRINE, ... 著者 Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. 登録日 2013-06-24 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502, 2013
4M2Y	Structure of human DNA polymerase beta complexed with 8-BrG as the template base in a 1-nucleotide gapped DNA 分子名称: DNA polymerase beta, SODIUM ION, down-primer, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-05 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
4QOM	Bacillus pumilus catalase with pyrogallol bound 分子名称: BENZENE-1,2,3-TRIOL, CHLORIDE ION, Catalase, ... 著者 Loewen, P.C. 登録日 2014-06-20 公開日 2015-02-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity of Bacillus pumilus catalase monitored by X-ray crystallography and EPR spectroscopy. Proteins, 83, 2015
4QGP	Crystal structure of a pyrophosphatase (AF1178) from Archaeoglobus fulgidus DSM 4304 at 1.80 A resolution 分子名称: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-05-23 公開日 2014-07-02 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure of a pyrophosphatase (AF1178) from Archaeoglobus fulgidus DSM 4304 at 1.80 A resolution To be published
1DPS	THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA 分子名称: DPS, SODIUM ION 著者 Grant, R.A, Filman, D.J, Finkel, S.E, Kolter, R, Hogle, J.M. 登録日 1998-02-23 公開日 1998-09-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The crystal structure of Dps, a ferritin homolog that binds and protects DNA. Nat.Struct.Biol., 5, 1998

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