1U2Y
| In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam | 分子名称: | (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | 著者 | Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors. J.Biol.Chem., 279, 2004
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1SMD
| HUMAN SALIVARY AMYLASE | 分子名称: | AMYLASE, CALCIUM ION, CHLORIDE ION | 著者 | Ramasubbu, N. | 登録日 | 1996-01-24 | 公開日 | 1996-07-11 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of human salivary alpha-amylase at 1.6 A resolution: implications for its role in the oral cavity. Acta Crystallogr.,Sect.D, 52, 1996
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1V3J
| Crystal structure of F283L mutant cyclodextrin glycosyltransferase | 分子名称: | CALCIUM ION, Cyclomaltodextrin glucanotransferase | 著者 | Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K. | 登録日 | 2003-11-03 | 公開日 | 2004-08-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site PROTEIN SCI., 13, 2004
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1TCM
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1VFO
| Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase 2/beta-cyclodextrin complex | 分子名称: | CALCIUM ION, Cyclic alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), ... | 著者 | Ohtaki, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | 登録日 | 2004-04-16 | 公開日 | 2005-02-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism J.BIOL.CHEM., 279, 2004
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1SMA
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1VFM
| Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase 2/alpha-cyclodextrin complex | 分子名称: | CALCIUM ION, Cyclic beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ... | 著者 | Ohtaki, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | 登録日 | 2004-04-16 | 公開日 | 2005-02-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism J.BIOL.CHEM., 279, 2004
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1VFU
| Crystal structure of Thermoactinomyces vulgaris R-47 amylase 2/gamma-cyclodextrin complex | 分子名称: | CALCIUM ION, Cyclooctakis-(1-4)-(alpha-D-glucopyranose), Neopullulanase 2 | 著者 | Ohtaki, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | 登録日 | 2004-04-19 | 公開日 | 2005-02-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism J.BIOL.CHEM., 279, 2004
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1VIW
| TENEBRIO MOLITOR ALPHA-AMYLASE-INHIBITOR COMPLEX | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, ALPHA-AMYLASE-INHIBITOR, ... | 著者 | Nahoum, V, Egloff, M.P, Payan, F. | 登録日 | 1998-07-21 | 公開日 | 1999-07-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A plant-seed inhibitor of two classes of alpha-amylases: X-ray analysis of Tenebrio molitor larvae alpha-amylase in complex with the bean Phaseolus vulgaris inhibitor. Acta Crystallogr.,Sect.D, 55, 1999
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1HT6
| CRYSTAL STRUCTURE AT 1.5A RESOLUTION OF THE BARLEY ALPHA-AMYLASE ISOZYME 1 | 分子名称: | 1,2-ETHANEDIOL, ALPHA-AMYLASE ISOZYME 1, CALCIUM ION | 著者 | Robert, X, Haser, R, Aghajari, N. | 登録日 | 2000-12-29 | 公開日 | 2003-07-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs Structure, 11, 2003
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1IZJ
| Thermoactinomyces vulgaris R-47 alpha-amylase 1 mutant enzyme f313a | 分子名称: | CALCIUM ION, amylase | 著者 | Ohtaki, A, Iguchi, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | 登録日 | 2002-10-03 | 公開日 | 2003-07-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mutual conversion of substrate specificities of Thermoactinomyces vulgaris R-47 alpha-amylases TVAI and TVAII by site-directed mutagenesis CARBOHYDR.RES., 338, 2003
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1J0J
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1IZK
| Thermoactinomyces vulgaris R-47 alpha-amylase 1 mutant enzyme w398v | 分子名称: | CALCIUM ION, amylase | 著者 | Ohtaki, A, Iguchi, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | 登録日 | 2002-10-03 | 公開日 | 2003-07-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mutual conversion of substrate specificities of Thermoactinomyces vulgaris R-47 alpha-amylases TVAI and TVAII by site-directed mutagenesis CARBOHYDR.RES., 338, 2003
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1JAE
| STRUCTURE OF TENEBRIO MOLITOR LARVAL ALPHA-AMYLASE | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION | 著者 | Strobl, S, Maskos, K, Betz, M, Wiegand, G, Huber, R, Gomis-Rueth, F.X, Frank, G, Glockshuber, R. | 登録日 | 1997-09-30 | 公開日 | 1998-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution. J.Mol.Biol., 278, 1998
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1JDA
| MALTOTETRAOSE-FORMING EXO-AMYLASE | 分子名称: | 1,4-ALPHA MALTOTETRAHYDROLASE, CALCIUM ION | 著者 | Yoshioka, Y, Hasegawa, K, Matsuura, Y, Katsube, Y, Kubota, M. | 登録日 | 1997-06-16 | 公開日 | 1997-10-15 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of a mutant maltotetraose-forming exo-amylase cocrystallized with maltopentaose. J.Mol.Biol., 271, 1997
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1KBK
| Mechanistic Analyses of Catalysis in Human Pancreatic Alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-06 | 公開日 | 2002-04-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41, 2002
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1KBB
| Mechanistic Analyses of Catalysis in Human Pancreatic alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-05 | 公開日 | 2002-04-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41, 2002
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1KCK
| Bacillus circulans strain 251 Cyclodextrin glycosyl transferase mutant N193G | 分子名称: | 1-AMINO-2,3-DIHYDROXY-5-HYDROXYMETHYL CYCLOHEX-5-ENE, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ... | 著者 | Rozeboom, H.J, Uitdehaag, J.C.M, Dijkstra, B.W. | 登録日 | 2001-11-09 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism. J.Biol.Chem., 277, 2002
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1KCL
| Bacillus ciruclans strain 251 Cyclodextrin glycosyl transferase mutant G179L | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cyclodextrin glycosyltransferase, ... | 著者 | Rozeboom, H.J, Uitdehaag, J.C.M, Dijkstra, B.W. | 登録日 | 2001-11-09 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism. J.Biol.Chem., 277, 2002
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1JFH
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1JD7
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1KGU
| THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337A VARIANT OF HUMAN PANCREATIC ALPHA-AMYLASE | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-28 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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1KGW
| THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337Q VARIANT OF HUMAN PANCREATIC ALPHA-MYLASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-28 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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1KXQ
| Camelid VHH Domain in Complex with Porcine Pancreatic alpha-Amylase | 分子名称: | CALCIUM ION, CHLORIDE ION, alpha-amylase, ... | 著者 | Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C. | 登録日 | 2002-02-01 | 公開日 | 2002-06-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology. J.Biol.Chem., 277, 2002
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1KB3
| Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-05 | 公開日 | 2002-05-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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