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4DCD
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1.6A resolution structure of PolioVirus 3C Protease Containing a covalently bound dipeptidyl inhibitor
分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Genome polyprotein, ...
著者Lovell, S, Battaile, K.P, Kim, Y, Tiew, K.-C, Mandadapu, S.R, Alliston, K.R, Groutas, W.C, Chang, K.O.
登録日2012-01-17
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses.
J.Virol., 86, 2012
4F49
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2.25A resolution structure of Transmissible Gastroenteritis Virus Protease containing a covalently bound Dipeptidyl Inhibitor
分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, TETRAETHYLENE GLYCOL
著者Lovell, S, Battaile, K.P, Kim, Y, Tiew, K.-C, Mandadapu, S.R, Alliston, K.R, Groutas, W.C, Chang, K.-O.
登録日2012-05-10
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses.
J.Virol., 86, 2012
4QPG
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Crystal structure of empty hepatitis A virus
分子名称: CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ...
著者Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2014-06-23
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
4QPI
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Crystal structure of hepatitis A virus
分子名称: CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ...
著者Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2014-06-23
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
3J22
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The Enterovirus 71 A-particle
分子名称: capsid protein VP0, capsid protein VP1, capsid protein VP3
著者Shingler, K.L.
登録日2012-08-13
公開日2013-04-03
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating.
Plos Pathog., 9, 2013
3J23
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The Enterovirus 71 empty capsid
分子名称: capsid protein VP0, capsid protein VP1, capsid protein VP3
著者Shingler, K.L.
登録日2012-08-13
公開日2013-04-03
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.2 Å)
主引用文献The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating.
Plos Pathog., 9, 2013
1VBD
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POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBE
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POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBA
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BU of 1vba by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBB
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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BU of 1vbc by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1HRI
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BU of 1hri by Molmil
STRUCTURE DETERMINATION OF ANTIVIRAL COMPOUND SCH 38057 COMPLEXED WITH HUMAN RHINOVIRUS 14
分子名称: 1-[6-(2-CHLORO-4-METHYXYPHENOXY)-HEXYL]-IMIDAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Zhang, A, Nanni, R.G, Oren, D.A, Arnold, E.
登録日1992-10-01
公開日1993-10-31
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure determination of antiviral compound SCH 38057 complexed with human rhinovirus 14.
J.Mol.Biol., 230, 1993
2PLV
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BU of 2plv by Molmil
STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
分子名称: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
著者Filman, D.J, Hogle, J.M.
登録日1989-10-17
公開日1989-10-17
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
1EAH
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BU of 1eah by Molmil
PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973
分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4
著者Lentz, K, Arnold, E.
登録日1997-07-22
公開日1998-09-16
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes.
Structure, 5, 1997
2BBP
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BU of 2bbp by Molmil
NMR structures of the peptide linked to the genome (VPg) of poliovirus
分子名称: Genome linked protein VPg
著者Schein, C.H, Oezguen, N.
登録日2005-10-17
公開日2006-03-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the viral peptide linked to the genome (VPg) of poliovirus.
Peptides, 27, 2006
4WZQ
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BU of 4wzq by Molmil
Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA
分子名称: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2014-11-20
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4WZM
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BU of 4wzm by Molmil
Mutant K18E of RNA dependent RNA polymerase from Foot-and-Mouth Disease Virus complexed with RNA
分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Verdaguer, N, Ferrer-Orta, C, de la Higuera, N.
登録日2014-11-20
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4X2B
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BU of 4x2b by Molmil
K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA
分子名称: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2014-11-26
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4WYW
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BU of 4wyw by Molmil
Mutant K20E of 3D polymerase from Foot-and-Mouth Disease Virus
分子名称: ACETATE ION, GLYCEROL, RNA-directed RNA polymerase 3D-POL, ...
著者Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E.
登録日2014-11-18
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
1C8M
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REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS
分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION
著者Chakravarty, S, Bator, C.M, Pevear, D.C, Diana, G.D, Rossmann, M.G.
登録日2000-05-26
公開日2000-11-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献THE REFINED STRUCTURE OF A PICORNAVIRUS INHIBITOR CURRENTLY IN CLINICAL TRIALS, WHEN COMPLEXED WITH HUMAN RHINOVIRUS 16
to be published
7ZV1
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Crystal Structure of Aichivirus A 2A protein L64M, L109M mutant
分子名称: Protein 2A
著者von Castelmur, E, Perrakis, A.
登録日2022-05-13
公開日2023-05-31
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural and functional repurposing of picornavirus H/NC-motif 2A proteins
To Be Published
7ZV6
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Crystal Structure of Aichivirus A 2A protein
分子名称: Protein 2A
著者von Castelmur, E, Perrakis, A.
登録日2022-05-13
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural and functional repurposing of picornavirus H/NC-motif 2A proteins
To Be Published
6P9W
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Poliovirus (Type 1 Mahoney), receptor catalysed 135S particle map
分子名称: VP1, VP2, VP3
著者Hogle, J.M, Filman, D.J, Shah, P.N.M.
登録日2019-06-10
公開日2020-06-10
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
6P9O
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Poliovirus 135S-like expanded particle in complex with a monoclonal antibody directed against the N-terminal extension of capsid protein VP1
分子名称: VP1, VP2, VP3
著者Hogle, J.M, Filman, D.J, Shah, P.N.M.
登録日2019-06-10
公開日2020-06-10
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
6PSZ
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BU of 6psz by Molmil
Poliovirus (Type 1 Mahoney), heat-catalysed 135S particle
分子名称: VP1, VP2, VP3
著者Hogle, J.M, Filman, D.J, Shah, P.N.M.
登録日2019-07-14
公開日2020-07-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020

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