PDB: 2244 件ウェブページステータス検索Chemie searchBIRD

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2M0A	Solution structure of MHV nsp3a 分子名称: Non-structural protein 3 著者 Keane, S.C, Giedroc, D.P. 登録日 2012-10-23 公開日 2013-01-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Mouse Hepatitis Virus (MHV) nsp3a and Determinants of the Interaction with MHV Nucleocapsid (N) Protein. J.Virol., 87, 2013
6W7H	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 6-methyl-2-oxo-2,5-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Augelli-Szafran, C.E, Pathak, A.K, Wu, M. 登録日 2020-03-19 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8K	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 5,6-dimethyl-2-oxo-2,3-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Augelli-Szafran, C.E, Pathak, A.K, Wu, M. 登録日 2020-03-20 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8M	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-20 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8Q	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-1,2,5,6,7,8-hexahydroquinazoline-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6VUQ	Crystal structure of CHIKV nsP3 macrodomain soaked with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Nonstructural polyprotein 著者 Wu, M. 登録日 2020-02-16 公開日 2021-01-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8Z	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: Nonstructural polyprotein, methyl 2-oxo-1,2-dihydroquinazoline-4-carboxylate 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8Y	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-2,3-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W91	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: Nonstructural polyprotein, methyl 2-oxo-2,5-dihydropyrimidine-4-carboxylate 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
5GVI	Zebrafish USP30 in complex with Lys6-linked diubiquitin 分子名称: Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ubiquitin 著者 Sato, Y, Fukai, S. 登録日 2016-09-05 公開日 2017-09-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30 Nat. Struct. Mol. Biol., 24, 2017
4YPT	X-ray structural of three tandemly linked domains of nsp3 from murine hepatitis virus at 2.60 Angstroms resolution 分子名称: GLYCEROL, Replicase polyprotein 1ab, ZINC ION 著者 Chen, Y, Savinov, S.N, Mielech, A.M, Cao, T, Baker, S.C, Mesecar, A.D. 登録日 2015-03-13 公開日 2015-08-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6009 Å) 主引用文献 X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions. J.Biol.Chem., 290, 2015
8AZD	Structure of SARS-CoV-2 NSP3 macrodomain in complex with ADPR 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-05 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in the apo form To Be Published
8AZI	Structure of SARS-CoV-2 NSP3 macrodomain in complex with 2'-deoxy-ADPR 分子名称: 2'-deoxyadenosine 5'-diphosphoribose, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in the apo form To Be Published
8AZC	Structure of SARS-CoV-2 NSP3 macrodomain in the apo form 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-05 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in the apo form To Be Published
8AZL	Structure of SARS-CoV-2 NSP3 macrodomain in complex with 2'-deoxy-2'-fluoro-ADPR 分子名称: 2'-deoxyadenosine 5'-fluoro-diphosphoribose, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in complex with 2'-deoxy-2'-fluoro-ADPR To Be Published
8AZO	Structure of SARS-CoV-2 NSP3 macrodomain in complex with beta-ethyl-ADP 分子名称: Papain-like protease nsp3, beta-ethyl-adenosine diphosphate 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in complex with beta-ethyl-ADP To Be Published
8AZP	Structure of SARS-CoV-2 NSP3 macrodomain in complex with beta-methyl-ADP 分子名称: Papain-like protease nsp3, beta-methyl-adenosine diphosphate 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in complex with beta-methyl-ADP To Be Published
8AZM	Structure of SARS-CoV-2 NSP3 macrodomain in complex with 8Br-ADPR 分子名称: 8-bromoadenosine 5'-diphosphoribose, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in complex with 8Br-ADPR To Be Published
8AZN	Structure of SARS-CoV-2 NSP3 macrodomain in complex with alpha-1-O-Me-ADPR 分子名称: Adenosine 5'-diphosphoric acid beta-[(3beta,4beta-dihydroxy-5beta-methoxytetrahydrofuran-2alpha-yl)methyl] estere, Papain-like protease nsp3 著者 Sander, S, Tidow, H, Fliegert, R, Sandmann, M. 登録日 2022-09-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of SARS-CoV-2 NSP3 macrodomain in complex with alpha-1-O-Me-ADPR To Be Published
1LJ2	Recognition of eIF4G by Rotavirus NSP3 reveals a basis for mRNA circularization 分子名称: GOLD ION, NONSTRUCTURAL RNA-BINDING PROTEIN 34, eukaryotic protein synthesis initiation factor 著者 Groft, C.M, Burley, S.K. 登録日 2002-04-18 公開日 2002-07-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization. Mol.Cell, 9, 2002
5HOL	The crystal structure of the MERS-CoV macro domain with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ORF1a 著者 Lei, J, Hilgenfeld, R. 登録日 2016-01-19 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein. Antiviral Res., 149, 2018
8C1A	SARS-CoV-2 NSP3 macrodomain in complex with aztreonam 分子名称: 1,2-ETHANEDIOL, Replicase polyprotein 1ab, aztreonam 著者 Schuller, M, Ahel, I. 登録日 2022-12-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors. Pathogens, 12, 2023
8C19	SARS-CoV-2 NSP3 macrodomain in complex with 1-methyl-4-[5-(morpholin-4-ylcarbonyl)-2-furyl]-1H-pyrrolo[2,3-b]pyridine 分子名称: 1,2-ETHANEDIOL, Non-structural protein 3, [5-(1-methylpyrrolo[2,3-b]pyridin-4-yl)furan-2-yl]-morpholin-4-yl-methanone 著者 Schuller, M, Ahel, I. 登録日 2022-12-20 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors. Pathogens, 12, 2023
6WEY	High-resolution structure of the SARS-CoV-2 NSP3 Macro X domain 分子名称: Non-structural protein 3 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2020-04-03 公開日 2020-04-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3. Biochemistry, 59, 2020
1XJH	NMR structure of the redox switch domain of the E. coli Hsp33 分子名称: 33 kDa chaperonin, ZINC ION 著者 Won, H.S, Low, L.Y, De Guzman, R.N, Martinez-Yamout, M.A, Jakob, U, Dyson, H.J. 登録日 2004-09-23 公開日 2004-10-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The Zinc-dependent Redox Switch Domain of the Chaperone Hsp33 has a Novel Fold J.Mol.Biol., 341, 2004

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