8DAS
 
 | |
8DAT
 | |
8DAV
 | |
7OAT
 | | Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Petrovic, S, Heinemann, U, Roske, Y. | | 登録日 | 2021-04-20 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | | 主引用文献 | Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7MHS
 | | Structure of p97 (subunits A to E) with substrate engaged | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S. | | 登録日 | 2021-04-15 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Active conformation of the p97-p47 unfoldase complex.
Nat Commun, 13, 2022
|
|
7WUB
 | | Cryo-EM structure of dodecamer P97 | | 分子名称: | 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Liu, S, Wang, T. | | 登録日 | 2022-02-08 | | 公開日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure of dodecamer P97 at 2.99 Angstroms resolution
To Be Published
|
|
7VCT
 | | Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7VCS
 | | Human p97 double hexamer conformer II with ATPgammaS bound | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-03 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7VCX
 | | Human p97 single hexamer conformer II with ATPgammaS bound | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7VCU
 | | Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7VCV
 | | Human p97 single hexamer conformer I with ATPgammaS bound | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7K59
 | | Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | | 分子名称: | Transitional endoplasmic reticulum ATPase | | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | | 登録日 | 2020-09-16 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
|
|
7K57
 | | Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 | | 分子名称: | Transitional endoplasmic reticulum ATPase | | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | | 登録日 | 2020-09-16 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
|
|
7K56
 | | Structure of VCP dodecamer purified from H1299 cells | | 分子名称: | Transitional endoplasmic reticulum ATPase | | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | | 登録日 | 2020-09-16 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
|
|
7RLC
 | | Cryo-EM structure of human p97-A232E mutant bound to ATPgS. | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RL7
 | | Cryo-EM structure of human p97-R155H mutant bound to ATPgS. | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLJ
 | | Cryo-EM structure of human p97 bound to CB-5083 and ATPgS. | | 分子名称: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RL9
 | | Cryo-EM structure of human p97-R191Q mutant bound to ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RL6
 | | Cryo-EM structure of human p97-R155H mutant bound to ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLF
 | | Cryo-EM structure of human p97-E470D mutant bound to ATPgS. | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLI
 | | Cryo-EM structure of human p97 bound to CB-5083 and ADP. | | 分子名称: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLA
 | | Cryo-EM structure of human p97-R191Q mutant bound to ATPgS. | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLH
 | | Cryo-EM structure of human p97-D592N mutant bound to ATPgS. | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLG
 | | Cryo-EM structure of human p97-D592N mutant bound to ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
7RLD
 | | Cryo-EM structure of human p97-E470D mutant bound to ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
|
|
