PDB: 95 件ウェブページステータス検索Chemie searchBIRD

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3IBB	Propionyl-CoA Carboxylase Beta Subunit, D422A 分子名称: Propionyl-CoA carboxylase complex B subunit 著者 Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Pham, H, Melgar, M.M. 登録日 2009-07-15 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
1XNW	Acyl-CoA Carboxylase Beta Subunit from S. coelicolor (PccB), apo form #2, mutant D422I 分子名称: propionyl-CoA carboxylase complex B subunit 著者 Diacovich, L, Mitchell, D.L, Pham, H, Gago, G, Melgar, M.M, Khosla, C, Gramajo, H, Tsai, S.-C. 登録日 2004-10-05 公開日 2004-11-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the beta-Subunit of Acyl-CoA Carboxylase: Structure-Based Engineering of Substrate Specificity Biochemistry, 43, 2004
3MFM	Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase Subunit of Streptomyces coelicolor 分子名称: Propionyl-CoA carboxylase complex B subunit 著者 Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Melgar, M.M. 登録日 2010-04-02 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
3IAV	Propionyl-CoA Carboxylase Beta Subunit, D422V 分子名称: Propionyl-CoA carboxylase complex B subunit, SULFATE ION 著者 Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Pham, H, Melgar, M.M. 登録日 2009-07-14 公開日 2010-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
5CTB	Humanized yeast ACC carboxyltransferase domain bound to 6,7-dimethyl-1'-[(7-methyl-1H-indazol-5-yl)carbonyl]spiro[chromene-2,4'-piperidin]-4(3H)-one 分子名称: 6,7-dimethyl-1'-[(7-methyl-1H-indazol-5-yl)carbonyl]spiro[chromene-2,4'-piperidin]-4(3H)-one, Acetyl-CoA carboxylase, SULFATE ION 著者 Vajdos, F.F. 登録日 2015-07-23 公開日 2015-10-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015
5CTE	Humanized yeast ACC carboxyltransferase domain bound to 2,2-dimethylpropyl (1S)-1-methyl-8-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,8-diazaspiro[4.5]decane-2-carboxylate 分子名称: 2,2-dimethylpropyl (1S)-1-methyl-8-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,8-diazaspiro[4.5]decane-2-carboxylate, Acetyl-CoA carboxylase, SULFATE ION 著者 Vajdos, F.F. 登録日 2015-07-23 公開日 2015-10-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015
5CTC	Humanized yeast ACC carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate 分子名称: Acetyl-CoA carboxylase, SULFATE ION, tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate 著者 Vajdos, F.F. 登録日 2015-07-23 公開日 2015-10-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015
5FIF	Carboxyltransferase domain of a single-chain bacterial carboxylase 分子名称: 1,2-ETHANEDIOL, Carboxylase 著者 Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T. 登録日 2015-12-23 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.494 Å) 主引用文献 Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans. Structure, 24, 2016
1UYV	Acetyl-CoA carboxylase carboxyltransferase domain L1705I/V1967I mutant 分子名称: ACETYL-COA CARBOXYLASE 著者 Zhang, H, Tweel, B, Tong, L. 登録日 2004-03-02 公開日 2004-03-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA, 101, 2004
1VRG	Crystal structure of propionyl-CoA carboxylase, beta subunit (TM0716) from THERMOTOGA MARITIMA at 2.30 A resolution 分子名称: BICARBONATE ION, MAGNESIUM ION, propionyl-CoA carboxylase, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2005-02-22 公開日 2005-03-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of propionyl-CoA carboxylase, beta subunit (TM0716) from THERMOTOGA MARITIMA at 2.30 A resolution To be published
1W2X	Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186 分子名称: (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, ACETYL-COA CARBOXYLASE 著者 Zhang, H, Tweel, B, Li, J, Tong, L. 登録日 2004-07-09 公開日 2004-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186 Structure, 12, 2004
1UYT	Acetyl-CoA carboxylase carboxyltransferase domain 分子名称: ACETYL-COA CARBOXYLASE 著者 Zhang, H, Tweel, B, Tong, L. 登録日 2004-03-02 公開日 2004-03-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop. Proc.Natl.Acad.Sci.USA, 101, 2004
1UYS	Acetyl-CoA carboxylase carboxyltransferase domain in complex with inhibitor haloxyfop 分子名称: (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid, ACETYL-COA CARBOXYLASE 著者 Zhang, H, Tweel, B, Tong, L. 登録日 2004-03-02 公開日 2004-03-29 最終更新日 2012-06-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA, 101, 2004
1UYR	Acetyl-CoA Carboxylase Carboxyltransferase Domain in complex with inhibitor Diclofop 分子名称: 2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID, ACETYL-COA CARBOXYLASE 著者 Zhang, H, Tweel, B, Tong, L. 登録日 2004-03-02 公開日 2004-03-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA, 101, 2004
1X0U	Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii 分子名称: hypothetical methylmalonyl-CoA decarboxylase alpha subunit 著者 Kakuta, Y, Sueda, S, Kondo, H. 登録日 2005-03-29 公開日 2006-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii To be Published
3TV5	Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 1 分子名称: (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, Acetyl-CoA carboxylase 著者 Rajamohan, F, Marr, E, Reyes, A, Landro, J.A, Anderson, M.D, Corbett, J.W, Dirico, K.J, Harwood, J.H, Tu, M, Vajdos, F.F. 登録日 2011-09-19 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion. J.Biol.Chem., 286, 2011
3TVW	Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 4 分子名称: Acetyl-CoA carboxylase, [4-(2H-chromen-3-ylmethyl)piperazin-1-yl]-[3-(1H-pyrazol-5-yl)phenyl]methanone 著者 Rajamohan, F, Marr, E, Reyes, A, Landro, J.A, Anderson, M.D, Corbett, J.W, Dirico, K.J, Harwood, J.H, Tu, M, Vajdos, F.F. 登録日 2011-09-20 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion. J.Biol.Chem., 286, 2011
3FF6	Human ACC2 CT domain with CP-640186 分子名称: (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, Acetyl-CoA carboxylase 2 著者 Williams, S.P, Madauss, K.P, Burkhart, W.A. 登録日 2008-12-02 公開日 2009-05-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist. Acta Crystallogr.,Sect.D, 65, 2009
3H0Q	Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 3 分子名称: 4-({4-[(2-methylquinolin-6-yl)methyl]piperidin-1-yl}carbonyl)-2-phenylquinoline, Acetyl-CoA carboxylase 著者 Zhang, H, Tong, L. 登録日 2009-04-10 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg.Med.Chem.Lett., 20, 2010
3GF7	Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum apoprotein 分子名称: Glutaconyl-CoA decarboxylase subunit A, SULFATE ION 著者 Kress, D, Brugel, D, Buckel, W, Essen, L.-O. 登録日 2009-02-26 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases J.Biol.Chem., 284, 2009
5INI	Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics 分子名称: HEXANOYL-COENZYME A, Putative carboxyl transferase 著者 Valentic, T.R, Ray, L, Miyazawa, T, Withall, D.M, Song, L, Milligan, J.C, Osada, H, Tsai, S.C, Challis, G.L. 登録日 2016-03-07 公開日 2016-12-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units. Nat Commun, 7, 2016
3H0S	Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7 分子名称: 1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one, Acetyl-CoA carboxylase, SULFATE ION 著者 Vajdos, F. 登録日 2009-04-10 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg.Med.Chem.Lett., 20, 2010
5ING	A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender unit 分子名称: Putative carboxyl transferase 著者 Valentic, T.R, Ray, L, Miyazawa, T, Song, L, Withall, D.M, Milligan, J.C, Takahashi, S, Osada, H, Tsai, S.C, Challis, G.L. 登録日 2016-03-07 公開日 2016-12-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units. Nat Commun, 7, 2016
3TDC	Crystal Structure of Human Acetyl-CoA carboxylase 2 分子名称: 1-[3-({4-[(5S)-3,3-dimethyl-1-oxo-2-oxa-7-azaspiro[4.5]dec-7-yl]piperidin-1-yl}carbonyl)-1-benzothiophen-2-yl]-3-ethylurea, Acetyl-CoA carboxylase 2 variant 著者 Dougan, D.R, Mol, C.D. 登録日 2011-08-10 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
5IKL	Crystal structure of P. aeruginosa geranyl-CoA carboxylase (GCC), beta subunit 分子名称: Geranyl-CoA carboxylase, beta-subunit 著者 Huang, C.S, Jurado, A.R, Tong, L. 登録日 2016-03-03 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and substrate selectivity of the 750-kDa alpha6beta6 holoenzyme of geranyl-CoA carboxylase Nat Commun, 6, 2015

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