2W1B
 
 | | The structure of the efflux pump AcrB in complex with bile acid | | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B | | 著者 | Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. | | 登録日 | 2008-10-17 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | The Structure of the Efflux Pump Acrb in Complex with Bile Acid.
Mol.Membr.Biol., 25, 2008
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3AOA
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3AOB
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3AOC
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3AOD
 | | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket | | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, RIFAMPICIN | | 著者 | Nakashima, R, Sakurai, K, Yamaguchi, A. | | 登録日 | 2010-09-23 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Nature, 480, 2011
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3D9B
 | | Symmetric structure of E. coli AcrB | | 分子名称: | Acriflavine resistance protein B, NICKEL (II) ION | | 著者 | Veesler, D, Blangy, S, Cambillau, C, Sciara, G. | | 登録日 | 2008-05-27 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization.
Acta Crystallogr.,Sect.F, 64, 2008
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3K07
 | | Crystal structure of CusA | | 分子名称: | Cation efflux system protein cusA | | 著者 | Su, C.-C. | | 登録日 | 2009-09-24 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.521 Å) | | 主引用文献 | Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
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3K0I
 | | Crystal structure of Cu(I)CusA | | 分子名称: | COPPER (I) ION, Cation efflux system protein cusA | | 著者 | Su, C.-C. | | 登録日 | 2009-09-24 | | 公開日 | 2010-10-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (4.116 Å) | | 主引用文献 | Crystal structure of CusA
To be Published
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3KSO
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3KSS
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3NE5
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3NOC
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3NOG
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3T51
 | | Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex | | 分子名称: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | | 著者 | Su, C.-C, Long, F, Yu, E.W. | | 登録日 | 2011-07-26 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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3T53
 | | Crystal structures of the extrusion state of the CusBA adaptor-transporter complex | | 分子名称: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | | 著者 | Su, C.-C, Long, F, Yu, E.W. | | 登録日 | 2011-07-26 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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3T56
 | | Crystal structure of the pre-extrusion state of the CusBA adaptor-transporter complex | | 分子名称: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | | 著者 | Su, C.-C, Long, F, Yu, E.W. | | 登録日 | 2011-07-26 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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3W9H
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | Acriflavine resistance protein B, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | 著者 | Sakurai, K, Nagata, C, Nakashima, R, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3W9I
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3W9J
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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4C48
 | | Crystal structure of AcrB-AcrZ complex | | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | | 登録日 | 2013-09-02 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the AcrAB-TolC multidrug efflux pump.
Nature, 509, 2014
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4CDI
 | | Crystal structure of AcrB-AcrZ complex | | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN | | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | | 登録日 | 2013-10-31 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structure of the Acrab-Tolc Multidrug Efflux Pump.
Nature, 509, 2014
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4DNR
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4DNT
 | | Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, mutant | | 分子名称: | Cation efflux system protein CusA, Cation efflux system protein CusB | | 著者 | Su, C.-C, Long, F, Yu, E. | | 登録日 | 2012-02-09 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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4DOP
 | | Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, R mutant | | 分子名称: | Cation efflux system protein CusA, Cation efflux system protein CusB | | 著者 | Su, C.-C, Long, F, Yu, E. | | 登録日 | 2012-02-10 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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4DX5
 | | Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop | | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ... | | 著者 | Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. | | 登録日 | 2012-02-27 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc.Natl.Acad.Sci.USA, 109, 2012
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