PDB: 187 件ウェブページステータス検索Chemie searchBIRD

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5JLX	AntpHD with 15bp DNA duplex S-monothioated at Cytidine-8 分子名称: DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), Homeotic protein antennapedia, ... 著者 White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D. 登録日 2016-04-27 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.748 Å) 主引用文献 Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem, 17, 2016
4XID	AntpHD with 15bp DNA duplex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 White, M.A, Zandarashvili, L, Iwahara, J. 登録日 2015-01-06 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys.J., 109, 2015
6WIG	Structure of STENOFOLIA Protein HD domain bound with DNA 分子名称: DNA (5'-D(P*CP*TP*TP*GP*AP*AP*TP*AP*AP*AP*TP*CP*AP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*AP*AP*TP*GP*AP*TP*TP*TP*AP*TP*TP*CP*AP*AP*G)-3'), STENOFOLIA 著者 Deng, J, Peng, S, Pathak, P. 登録日 2020-04-09 公開日 2021-08-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the unique tetrameric STENOFOLIA homeodomain bound with target promoter DNA. Acta Crystallogr D Struct Biol, 77, 2021
4XIC	ANTPHD WITH 15BP di-thioate modified DNA DUPLEX 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 White, M.A, Zandarashvili, L, Iwahara, J. 登録日 2015-01-06 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys.J., 109, 2015
6U82	Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer containing bulge and loop 分子名称: DNA (38-MER), Double homeobox protein 4 著者 Shi, K, Aihara, H. 登録日 2019-09-04 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. Faseb J., 34, 2020
6U81	Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*CP*CP*CP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Shi, K, Aihara, H. 登録日 2019-09-04 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. Faseb J., 34, 2020
6DFY	Remodeled crystal structure of DNA-bound DUX4-HD2 分子名称: DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), Double homeobox protein 4 著者 Aihara, H, Shi, K. 登録日 2018-05-15 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
5LTY	Homeobox transcription factor CDX2 bound to methylated DNA 分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2 著者 Morgunova, E, Popov, A, Taipale, J. 登録日 2016-09-07 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
5LUX	Homeobox transcription factor CDX1 bound to methylated DNA 分子名称: DNA (5'-D(P*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*C)-3'), ... 著者 Morgunova, E, Popov, A, Taipale, J. 登録日 2016-09-12 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
3A03	Crystal structure of Hox11L1 homeodomain 分子名称: SODIUM ION, SULFATE ION, T-cell leukemia homeobox protein 2 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
3A01	Crystal structure of Aristaless and Clawless homeodomains bound to DNA 分子名称: 5'-D(*CP*CP*GP*CP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*GP*CP*GP*G)-3', Homeobox protein aristaless, ... 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
3A02	Crystal structure of Aristaless homeodomain 分子名称: CADMIUM ION, CHLORIDE ION, Homeobox protein aristaless 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
6ES3	Structure of CDX2-DNA(TCG) 分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2017-10-19 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife, 7, 2018
6E8C	Crystal structure of the double homeodomain of DUX4 in complex with DNA 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), Double homeobox protein 4 著者 Lee, J.K, Bosnakovski, D, Toso, E.A, Dinh, T, Banerjee, S, Bohl, T.E, Shi, K, Kurahashi, K, Kyba, M, Aihara, H. 登録日 2018-07-27 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Rep, 25, 2018
6ES2	Structure of CDX2-DNA(CAA) 分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2017-10-19 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife, 7, 2018
8P7G	Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS 分子名称: Paired mesoderm homeobox protein 2B 著者 Russo, L, Diana, D, Fattorusso, R. 登録日 2023-05-30 公開日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural characterization of PHOX2B and its DNA interaction shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS Chem Sci, 2024
8EJP	Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Yin, L.L, Shi, K, Aihara, H. 登録日 2022-09-18 公開日 2023-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.174 Å) 主引用文献 Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023
8EJO	Crystal structure of the homeodomain of Platypus sDUX in complex with DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Yin, L.L, Shi, K, Aihara, H. 登録日 2022-09-18 公開日 2023-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023
8F36	Ubx Homeodomain NMR solution structure 分子名称: Homeotic protein ultrabithorax 著者 Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ubx Homeodomain NMR solution structure To Be Published
8F37	AbdA Homeodomain NMR Solution Structure 分子名称: Homeobox protein abdominal-A 著者 Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 AbdA Homeodomain NMR solution structure To Be Published
8EML	Crystal Structure of Gsx2 Homeodomain in Complex with DNA 分子名称: DNA (5'-D(P*GP*AP*GP*CP*TP*AP*AP*TP*TP*AP*AP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*TP*TP*AP*AP*TP*TP*AP*GP*CP*TP*C)-3'), GS homeobox 2, ... 著者 Webb, J.A, Kovall, R.A. 登録日 2022-09-28 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal Structure of Gsx2 Homeodomain in Complex with DNA To Be Published
2N8G	NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens 分子名称: Homeobox protein GBX-1 著者 Proudfoot, A.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2015-10-15 公開日 2015-10-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens To be Published
2MW8	Solution structure of SATB1 homeodomain 分子名称: DNA-binding protein SATB1 著者 Yamasaki, K, Yamasaki, T. 登録日 2014-10-31 公開日 2015-11-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of SATB1 homeodomain To be Published
1AHD	DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX 分子名称: DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia 著者 Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. 登録日 1993-04-02 公開日 1993-10-31 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J.Mol.Biol., 234, 1993
1AKH	MAT A1/ALPHA2/DNA TERNARY COMPLEX 分子名称: DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ... 著者 Li, T, Jin, Y, Vershon, A.K, Wolberger, C. 登録日 1997-05-19 公開日 1998-05-20 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract. Nucleic Acids Res., 26, 1998

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