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4XIC
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BU of 4xic by Molmil
ANTPHD WITH 15BP di-thioate modified DNA DUPLEX
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
6U82
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BU of 6u82 by Molmil
Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer containing bulge and loop
分子名称: DNA (38-MER), Double homeobox protein 4
著者Shi, K, Aihara, H.
登録日2019-09-04
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD.
Faseb J., 34, 2020
1ZQ3
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BU of 1zq3 by Molmil
NMR Solution Structure of the Bicoid Homeodomain Bound to the Consensus DNA Binding Site TAATCC
分子名称: 5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3', Homeotic bicoid protein
著者Baird-Titus, J.M, Rance, M, Clark-Baldwin, K, Ma, J, Vrushank, D.
登録日2005-05-18
公開日2006-02-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site.
J.Mol.Biol., 356, 2006
1ZTR
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BU of 1ztr by Molmil
Solution structure of Engrailed homeodomain L16A mutant
分子名称: Segmentation polarity homeobox protein engrailed
著者Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R.
登録日2005-05-27
公開日2005-10-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of a protein denatured state and folding intermediate.
Nature, 437, 2005
6U81
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BU of 6u81 by Molmil
Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*CP*CP*CP*AP*TP*TP*AP*CP*GP*C)-3'), ...
著者Shi, K, Aihara, H.
登録日2019-09-04
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD.
Faseb J., 34, 2020
7Q3O
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BU of 7q3o by Molmil
Structure of CDX1 bound to hydroxymethylated DNA
分子名称: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER)
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2021-10-28
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structure of CDX1 bound to hydroxymethylated DNA
To Be Published
4XID
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BU of 4xid by Molmil
AntpHD with 15bp DNA duplex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
1BW5
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BU of 1bw5 by Molmil
THE NMR SOLUTION STRUCTURE OF THE HOMEODOMAIN OF THE RAT INSULIN GENE ENHANCER PROTEIN ISL-1, 50 STRUCTURES
分子名称: INSULIN GENE ENHANCER PROTEIN ISL-1
著者Ippel, J.H, Larsson, G, Behravan, G, Zdunek, J, Lundqvist, M, Schleucher, J, Lycksell, P.-O, Wijmenga, S.S.
登録日1998-09-29
公開日1999-06-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the homeodomain of the rat insulin-gene enhancer protein isl-1. Comparison with other homeodomains.
J.Mol.Biol., 288, 1999
8IKE
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BU of 8ike by Molmil
Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter
分子名称: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor
著者Lv, M.Q, Lin, L.Q.
登録日2023-02-28
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
6RYI
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BU of 6ryi by Molmil
WUS-HD bound to G-Box DNA
分子名称: DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*CP*GP*TP*GP*AP*CP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*TP*CP*AP*CP*GP*TP*GP*AP*TP*GP*GP*G)-3'), Protein WUSCHEL
著者Sloan, J.J, Wild, K, Sinning, I.
登録日2019-06-10
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
8IK5
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BU of 8ik5 by Molmil
Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter
分子名称: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ...
著者Lv, M.Q, Lin, L.Q.
登録日2023-02-28
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.989 Å)
主引用文献Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8ILW
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BU of 8ilw by Molmil
Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter
分子名称: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor
著者Lv, M.Q, Lin, L.Q.
登録日2023-03-04
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
6WIG
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BU of 6wig by Molmil
Structure of STENOFOLIA Protein HD domain bound with DNA
分子名称: DNA (5'-D(P*CP*TP*TP*GP*AP*AP*TP*AP*AP*AP*TP*CP*AP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*AP*AP*TP*GP*AP*TP*TP*TP*AP*TP*TP*CP*AP*AP*G)-3'), STENOFOLIA
著者Deng, J, Peng, S, Pathak, P.
登録日2020-04-09
公開日2021-08-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the unique tetrameric STENOFOLIA homeodomain bound with target promoter DNA.
Acta Crystallogr D Struct Biol, 77, 2021
6RY3
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BU of 6ry3 by Molmil
Structure of the WUS homeodomain
分子名称: ACETYL GROUP, Protein WUSCHEL, SULFATE ION
著者Sloan, J.J, Wild, K, Sinning, I.
登録日2019-06-10
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.374 Å)
主引用文献Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
1UHS
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BU of 1uhs by Molmil
Solution structure of mouse homeodomain-only protein HOP
分子名称: homeodomain only protein
著者Saito, K, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-10
公開日2004-07-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of mouse homeodomain-only protein HOP
To be Published
1VND
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BU of 1vnd by Molmil
VND/NK-2 PROTEIN (HOMEODOMAIN), NMR
分子名称: VND/NK-2 PROTEIN
著者Tsao, D.H.H, Gruschus, J.M, Wang, L.-H, Nirenberg, M, Ferretti, J.A.
登録日1996-05-22
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional solution structure of the NK-2 homeodomain from Drosophila.
J.Mol.Biol., 251, 1995
1DU0
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BU of 1du0 by Molmil
ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), ENGRAILED HOMEODOMAIN
著者Grant, R.A, Rould, M.A, Klemm, J.D, Pabo, C.O.
登録日2000-01-13
公開日2000-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
6RYD
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BU of 6ryd by Molmil
WUS-HD bound to TGAA DNA
分子名称: DNA (5'-D(*AP*GP*TP*GP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*CP*AP*CP*T)-3'), MAGNESIUM ION, ...
著者Sloan, J.J, Wild, K, Sinning, I.
登録日2019-06-10
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.575 Å)
主引用文献Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
6RYL
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BU of 6ryl by Molmil
WUS-HD bound to TAAT DNA
分子名称: DNA (5'-D(P*CP*AP*CP*AP*AP*CP*CP*CP*AP*TP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*TP*AP*AP*TP*GP*GP*GP*TP*TP*GP*TP*G)-3'), Protein WUSCHEL
著者Sloan, J.J, Wild, K, Sinning, I.
登録日2019-06-10
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
1WI3
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BU of 1wi3 by Molmil
Solution structure of the homeodomain of KIAA1034 protein
分子名称: DNA-binding protein SATB2
著者Izumi, K, Yoshida, M, Hayashi, F, Hatta, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the homeodomain of KIAA1034 protein
TO BE PUBLISHED
1X2M
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BU of 1x2m by Molmil
Solution structure of the homeobox domain of mouse LAG1 longevity assurance homolog 6
分子名称: LAG1 longevity assurance homolog 6
著者Kamatari, Y.O, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-04-26
公開日2005-10-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the homeobox domain of mouse LAG1 longevity assurance homolog 6
To be Published
3A03
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BU of 3a03 by Molmil
Crystal structure of Hox11L1 homeodomain
分子名称: SODIUM ION, SULFATE ION, T-cell leukemia homeobox protein 2
著者Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M.
登録日2009-02-28
公開日2010-03-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless
Embo J., 29, 2010
3A01
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BU of 3a01 by Molmil
Crystal structure of Aristaless and Clawless homeodomains bound to DNA
分子名称: 5'-D(*CP*CP*GP*CP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*GP*CP*GP*G)-3', Homeobox protein aristaless, ...
著者Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M.
登録日2009-02-28
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless
Embo J., 29, 2010
3A02
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BU of 3a02 by Molmil
Crystal structure of Aristaless homeodomain
分子名称: CADMIUM ION, CHLORIDE ION, Homeobox protein aristaless
著者Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M.
登録日2009-02-28
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless
Embo J., 29, 2010
6E8C
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BU of 6e8c by Molmil
Crystal structure of the double homeodomain of DUX4 in complex with DNA
分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), Double homeobox protein 4
著者Lee, J.K, Bosnakovski, D, Toso, E.A, Dinh, T, Banerjee, S, Bohl, T.E, Shi, K, Kurahashi, K, Kyba, M, Aihara, H.
登録日2018-07-27
公開日2018-12-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.
Cell Rep, 25, 2018

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件を2024-10-16に公開中

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