PDB: 136 件ウェブページステータス検索Chemie searchBIRD

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3RKI	Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A. 登録日 2011-04-18 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. Proc.Natl.Acad.Sci.USA, 108, 2011
1SVF	PARAMYXOVIRUS SV5 FUSION PROTEIN CORE 分子名称: CHLORIDE ION, PROTEIN (FUSION GLYCOPROTEIN) 著者 Baker, K.A, Dutch, R.E, Lamb, R.A, Jardetzky, T.S. 登録日 1999-02-27 公開日 1999-03-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural basis for paramyxovirus-mediated membrane fusion. Mol.Cell, 3, 1999
4JHW	Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25 分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0 著者 Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S. 登録日 2013-03-05 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340, 2013
6DC3	RSV prefusion F bound to RSD5 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ... 著者 Battles, M.B, McLellan, J.S, Jones, H.J. 登録日 2018-05-04 公開日 2019-07-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.501 Å) 主引用文献 Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
6DC5	RSV prefusion F in complex with AM22 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Jones, H.G, McLellan, J.S. 登録日 2018-05-04 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
1WP8	crystal structure of Hendra Virus fusion core 分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0 著者 Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z. 登録日 2004-08-31 公開日 2005-11-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of Nipah and Hendra virus fusion core proteins FEBS J., 273, 2006
3KPE	Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV 分子名称: 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol, Fusion glycoprotein F0, TETRAETHYLENE GLYCOL 著者 Roymans, D, De Bondt, H, Arnoult, E, Cummings, M.D, Van Vlijmen, H, Andries, K. 登録日 2009-11-16 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. Proc.Natl.Acad.Sci.USA, 107, 2010
8T7A	Cryo-EM structure of RSV preF in complex with Fab 2.4K 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.4K Fab Heavy Chain, 2.4K Fab Light Chain, ... 著者 McCool, R.S, McLellan, J.S. 登録日 2023-06-20 公開日 2023-09-13 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope. J.Virol., 97, 2023
4GIP	Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2 著者 Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A. 登録日 2012-08-08 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc.Natl.Acad.Sci.USA, 109, 2012
7MMN	Crystal Structure of the Prefusion RSV F Glycoprotein bound by human antibody AM14 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab Heavy Chain, AM14 Fab Light Chain, ... 著者 Harshbarger, W, Malito, E. 登録日 2021-04-29 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein. Mabs, 13, 2021
1ZTM	Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein 著者 Yin, H.S, Paterson, R.G, Wen, X, Lamb, R.A, Jardetzky, T.S. 登録日 2005-05-27 公開日 2005-07-19 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein Proc.Natl.Acad.Sci.USA, 102, 2005
3IXT	Crystal Structure of Motavizumab Fab Bound to Peptide Epitope 分子名称: 1,2-ETHANEDIOL, Fusion glycoprotein F1, Motavizumab Fab heavy chain, ... 著者 McLellan, J.S, Chen, M, Kim, A, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2009-09-04 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis of respiratory syncytial virus neutralization by motavizumab. Nat.Struct.Mol.Biol., 17, 2010
5J3D	Crystal structure of human Fab 14N4 in complex with post-fusion RSV F 分子名称: 14N4 heavy chain, 14N4 light chain, Fusion glycoprotein F0 著者 Mousa, J.J, Crowe, J.E. 登録日 2016-03-30 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.077 Å) 主引用文献 Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
6T3F	Crystal structure Nipah virus fusion glycoprotein in complex with a neutralising Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab66 heavy chain, ... 著者 Avanzato, V.A, Pryce, R, Walter, T.S, Bowden, T.A. 登録日 2019-10-10 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex. Proc.Natl.Acad.Sci.USA, 116, 2019
6TYS	A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ... 著者 Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-08-09 公開日 2019-10-09 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
6V3V	Assembly of VIQKI I456(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain 分子名称: Fusion glycoprotein F1 著者 Outlaw, V.K, Gellman, S.H. 登録日 2019-11-26 公開日 2020-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Effects of Single alpha-to-beta Residue Replacements on Recognition of an Extended Segment in a Viral Fusion Protein. Acs Infect Dis., 6, 2020
8DMJ	Postfusion Nipah virus fusion protein in complex with Fab 1H1 分子名称: Fusion glycoprotein F0,Fusion glycoprotein F1, antibody 1H1 heavy chain, antibody 1H1 light chain 著者 Byrne, P.O, Blade, E.G, McLellan, J.S. 登録日 2022-07-08 公開日 2023-07-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Postfusion Nipah virus fusion protein in complex with Fab 1H1 To Be Published
6VAS	Assembly of VIQKI I454(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain 分子名称: Fusion glycoprotein F0 著者 Outlaw, V.K, Gellman, S.H. 登録日 2019-12-17 公開日 2020-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Effects of Single alpha-to-beta Residue Replacements on Recognition of an Extended Segment in a Viral Fusion Protein. Acs Infect Dis., 6, 2020
8DO4	Prefusion-stabilized Nipah virus fusion protein, dimer of trimers 分子名称: Fusion glycoprotein F0 著者 Byrne, P.O, Blade, E.G, McLellan, J.S. 登録日 2022-07-12 公開日 2023-07-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Prefusion stabilization of the Hendra and Langya virus F proteins. J.Virol., 98, 2024
8DNG	Prefusion-stabilized Nipah virus fusion protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Byrne, P.O, Blade, E.G, McLellan, J.S. 登録日 2022-07-11 公開日 2023-07-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Prefusion stabilization of the Hendra and Langya virus F proteins. J.Virol., 98, 2024
8DNR	Prefusion-stabilized Hendra virus fusion protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Byrne, P.O, Blade, E.G, McLellan, J.S. 登録日 2022-07-11 公開日 2023-07-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Prefusion stabilization of the Hendra and Langya virus F proteins. J.Virol., 98, 2024
3O41	Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope 分子名称: Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ... 著者 McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. 登録日 2010-07-26 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F. J.Virol., 84, 2010
3MAW	Structure of the Newcastle disease virus F protein in the post-fusion conformation 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Jardetzky, T.S, Wen, X. 登録日 2010-03-24 公開日 2010-05-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of the Newcastle disease virus F protein in the post-fusion conformation. Virology, 402, 2010
3N27	Molecular Basis of the Inhibition of Henipa Viruses 分子名称: CITRIC ACID, Fusion glycoprotein F0, linker, ... 著者 Liu, J, Lu, M. 登録日 2010-05-17 公開日 2011-06-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular Basis of the Inhibition of Henipa Viruses To be Published
7KI4	Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody 分子名称: 12B2 Fab light chain, 12B2 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dang, H.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. 登録日 2020-10-23 公開日 2021-05-05 最終更新日 2021-05-26 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins. Nat.Struct.Mol.Biol., 28, 2021

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