6H2T
 
 | | GlnH bound to Glu, Mycobacterium tuberculosis | | 分子名称: | GLUTAMIC ACID, Probable glutamine-binding lipoprotein GlnH (GLNBP) | | 著者 | O'Hare, H.M, Wallis, R, Lin, L.Y, Newland-Smith, Z. | | 登録日 | 2018-07-16 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria.
MBio, 9, 2018
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5JC1
 | | Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC55 and manganese | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... | | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | | 登録日 | 2016-04-14 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin.
Chemmedchem, 11, 2016
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7RAP
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2VSU
 | | A ternary complex of Hydroxycinnamoyl-CoA Hydratase-Lyase (HCHL) with acetyl-Coenzyme A and vanillin gives insights into substrate specificity and mechanism. | | 分子名称: | 4-hydroxy-3-methoxybenzaldehyde, ACETYL COENZYME *A, P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE | | 著者 | Bennett, J.P, Bertin, L.M, Brzozowski, A.M, Walton, N.J, Grogan, G. | | 登録日 | 2008-04-29 | | 公開日 | 2008-05-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Ternary Complex of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) with Acetyl-Coa and Vanillin Gives Insights Into Substrate Specificity and Mechanism.
Biochem.J., 414, 2008
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2HEO
 | | General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers. | | 分子名称: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 | | 著者 | Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P. | | 登録日 | 2006-06-21 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
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8SAW
 | | CryoEM structure of DH270.UCA.G57R-CH848.10.17DT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp120A, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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1LBT
 | | LIPASE (E.C.3.1.1.3) (TRIACYLGLYCEROL HYDROLASE) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIPASE B, METHYLPENTA(OXYETHYL) HEPTADECANOATE | | 著者 | Uppenberg, J, Jones, T.A. | | 登録日 | 1995-07-11 | | 公開日 | 1995-10-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols.
Biochemistry, 34, 1995
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8SAN
 | | CryoEM structure of VRC01-CH848.0836.10 | | 分子名称: | CH848.0836.10 gp120, CH848.0836.10 gp41, VCR01 variable heavy chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAU
 | | CryoEM structure of DH270.4-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAR
 | | CryoEM structure of DH270.6-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAQ
 | | CryoEM structure of DH270.6-CH848.0526.25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, CH848.0526.25 gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB2
 | | CryoEM structure of DH270.I2-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAV
 | | CryoEM structure of VRC01-CH848.0526.25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAX
 | | CryoEM structure of DH270.UCA-CH848.10.17DT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAZ
 | | CryoEM structure of DH270.I5.6-CH848.10.17 | | 分子名称: | CH848.10.17.SOSIP gp41, DH270.I5.6 variable heavy chain, DH270.I5.6 variable light chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB4
 | | CryoEM structure of DH270.1-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB0
 | | CryoEM structure of DH270.I4.6-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAY
 | | CryoEM structure of DH270.3-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAL
 | | CryoEM structure of VRC01-CH848.0358.80 | | 分子名称: | CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp120, CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp41, VCR01 variable heavy chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB3
 | | CryoEM structure of DH270.2-CH848.10.17 | | 分子名称: | CH848.10.17 gp120, CH848.10.17.SOSIP gp41, DH270.2 Variable Heavy chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAT
 | | CryoEM structure of VRC01-CH848.10.17 | | 分子名称: | CH848.10.17 gp120, CH848.10.17 gp41, VRC01-variable heavy chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB1
 | | CryoEM structure of DH270.I3-CH848.10.17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17.SOSIP gp41, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SAS
 | | CryoEM structure of DH270.5-CH848.10.17 | | 分子名称: | CH848.10.17 gp120, CH848.10.17 gp41, DH270.5 variable heavy chian, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8SB5
 | | CryoEM structure of DH270.I1.6-CH848.10.17 | | 分子名称: | CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, DH270.I1.6 variable heavy chain, ... | | 著者 | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | | 登録日 | 2023-04-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
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8C13
 | | Crystal structure of pVHL:ElonginC:ElonginB complex bound to PROTAC JW48 | | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[3-[2-[2-[2-(acetamidomethyl)-4-(6,7-dihydro-5~{H}-pyrrolo[1,2-a]imidazol-2-yl)phenoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Kraemer, A, Weckesser, J, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2022-12-20 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization.
Cell Chem Biol, 30, 2023
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